This invention relates to polyurethane-based pressure sensitive adhesive compositions that comprise curable moieties. The adhesive compositions are “switchable” from a tacky state to a non-tacky state by initiating curing of the curable moieties. The adhesive compositions comprise the reaction product of: (A) a polymer component containing at least 2 nucleophilic functional groups containing an active hydrogen atom; and (B) a crosslinking component that is obtainable by reacting a polyisocyanate component and a ompound comprising a functional group that is curable by free-radical polymerisation and further comprising a nucleophilic functional group containing an active hydrogen atom.

The present disclosure provides an adhesive composition including a silicone-based adhesive and cellulose nanocrystals dispersed in the silicone-based adhesive. The present disclosure also provides an article including a substrate and a layer of the adhesive composition adhered to the substrate. Further, the present disclosure provides a method of making an adhesive composition. The method comprises mixing cellulose nanocrystals in a silicone-based adhesive to disperse the cellulose nanocrystals. The present disclosure additionally provides a method of making an article including disposing a layer of the adhesive composition on a substrate. The presence of the cellulose nanocrystals advantageously increases the water uptake capacity of the silicone-based adhesive while maintaining acceptable adhesive performance.

The present disclosure provides an adhesive composition including a silicone-based adhesive and cellulose nanocrystals dispersed in the silicone-based adhesive. The present disclosure also provides an article including a substrate and a layer of the adhesive composition adhered to the substrate. Further, the present disclosure provides a method of making an adhesive composition. The method comprises mixing cellulose nanocrystals in a silicone-based adhesive to disperse the cellulose nanocrystals. The present disclosure additionally provides a method of making an article including disposing a layer of the adhesive composition on a substrate. The presence of the cellulose nanocrystals advantageously increases the water uptake capacity of the silicone-based adhesive while maintaining acceptable adhesive performance.

A laminate including a substrate layer and a fibrous layer. The fibrous layer includes cellulose fibers and irregularly shaped lumps of a hotmelt material. The lumps of hotmelt material may at least partially bond the cellulose fibers together, thus increasing the integrity and resilience of the fibrous layer.

A fibrous layer having a first side and an opposed second side. The fibrous layer includes a hotmelt composition that at least partially coats and binds the fibers of the fibrous layer at the surface of at least one of the first side and second side.

A fibrous layer having a first side and an opposed second side. The fibrous layer includes a hotmelt composition that at least partially coats and binds the fibers of the fibrous layer at the surface of at least one of the first side and second side.

A method for manufacturing a medical tape includes: applying a solution polymer serving as an elastic base member portion having an elastic function to an upper layer of a film forming base portion having an inelastic function to form a film of the solution polymer; laminating an adhesion portion having a function to apply and hold the elastic base member portion to a skin on an upper layer of the elastic base member portion, and laminating a release portion having a function to protect the adhesion portion on an upper layer of the adhesion portion; peeling and removing the film forming base portion from the elastic base member portion to obtain the elastic base member portion in a state where a residual shrink force generated by a forming shrinkage of the solution polymer is reduced and to obtain a three-layer structure consisting of the elastic base member portion.

A method for manufacturing a medical tape includes: applying a solution polymer serving as an elastic base member portion having an elastic function to an upper layer of a film forming base portion having an inelastic function to form a film of the solution polymer; laminating an adhesion portion having a function to apply and hold the elastic base member portion to a skin on an upper layer of the elastic base member portion, and laminating a release portion having a function to protect the adhesion portion on an upper layer of the adhesion portion; peeling and removing the film forming base portion from the elastic base member portion to obtain the elastic base member portion in a state where a residual shrink force generated by a forming shrinkage of the solution polymer is reduced and to obtain a three-layer structure consisting of the elastic base member portion.

There are provided herein bioadhesive compositions which include at least one catechol derivatives, such as, caffeic acid derivatives, and at least one synthetic thermoplastic polymer, wherein exposure to heat causes the bioadhesive composition to transform into a non-solid state and to cohesively adhere to a biological tissue upon subsequent cooling. Further provided are methods of making the compositions and uses thereof in repairing tissue damage, such as, for example, in hernia repair surgeries.

There are provided herein bioadhesive compositions which include at least one catechol derivatives, such as, caffeic acid derivatives, and at least one synthetic thermoplastic polymer, wherein exposure to heat causes the bioadhesive composition to transform into a non-solid state and to cohesively adhere to a biological tissue upon subsequent cooling. Further provided are methods of making the compositions and uses thereof in repairing tissue damage, such as, for example, in hernia repair surgeries.