A method of attaching a release liner to a sanitary pad is disclosed. The method comprises: applying a pattern of adhesive, preferably water based pressure sensitive adhesive, to a sheet of release liner material; drying a sheet of release liner material comprising an adhesive pattern; overlaying a sanitary pad on the dried release liner material and adhesive pattern; and compressing the overlaid sanitary pad and dried release liner together so as to adhere the dried adhesive to the sanitary pad.

This invention provides a cell line of M2C macrophage and its applications. The cell line is derived from monocytes isolated from bone marrows and peripheral blood. The monocytes were differentiated into M2 macrophage by macrophage colony-stimulating factor (M-CSF), and then the polarization of M2C macrophage was induced by baicalin. The MERTK, PTX3, and PD-L1 expression level of the M2C macrophage are high and promote phagocytosis. Hence it can be applied to cell therapy or biological agents of immune regulation. Also, the macrophage-conditioned medium and wound dressing prepared on the M2C cell have the effects of enhancing fibroblast proliferation and angiogenesis, which can improve wound healing in medical use, and can be applied to skin care product for skin repair and rejuvenation.

This invention provides a cell line of M2C macrophage and its applications. The cell line is derived from monocytes isolated from bone marrows and peripheral blood. The monocytes were differentiated into M2 macrophage by macrophage colony-stimulating factor (M-CSF), and then the polarization of M2C macrophage was induced by baicalin. The MERTK, PTX3, and PD-L1 expression level of the M2C macrophage are high and promote phagocytosis. Hence it can be applied to cell therapy or biological agents of immune regulation. Also, the macrophage-conditioned medium and wound dressing prepared on the M2C cell have the effects of enhancing fibroblast proliferation and angiogenesis, which can improve wound healing in medical use, and can be applied to skin care product for skin repair and rejuvenation.

Provided is a biodegradable water absorbent having high gel strength and exhibiting an excellent absorption factor and excellent liquid passage rate through a gel. A water absorbent comprising a cross-linked naturally derived polymer and a clay mineral, the water absorbent being characterized in that the cross-linked naturally derived polymer and the clay mineral form particles, the clay mineral is present in the interior of the particles, and the clay mineral content constitutes 10-100 parts by mass (when dry) relative to 100 parts by mass (when dry) of the cross-linked naturally derived polymer. It is possible to produce this water absorbent by preparing a starting material fluid in which the naturally derived polymer is dissolved and the clay mineral is dispersed, adding a cross-linking agent to the starting material fluid, and cross-linking the naturally derived polymer.

A method is described for exfoliating a microcrystal of an anthracene derivative by irradiation with short pulses of light having a wavelength of 220-420 nm. The irradiation induces a cis-trans isomerization of the anthracene derivative in a part of the microcrystal, which leads to the separation of an outer layer having a thickness of 200-600 nm. The exfoliated microcrystal may be irradiated again with pulses of light of a same or different wavelength.

A method is described for exfoliating a microcrystal of an anthracene derivative by irradiation with short pulses of light having a wavelength of 220-420 nm. The irradiation induces a cis-trans isomerization of the anthracene derivative in a part of the microcrystal, which leads to the separation of an outer layer having a thickness of 200-600 nm. The exfoliated microcrystal may be irradiated again with pulses of light of a same or different wavelength.

Disclosed is an absorbent article with biocompostable properties, such as a baby diaper or adult incontinence product. Particularly, the present invention is directed to a biocompostable absorbent sanitary article including a blend of synthetic and bio-based superabsorbent polymers with a high degree of biocompostability. The sanitary article comprises, in one embodiment, at least a top layer, a back layer, and absorbent core, wherein the absorbent core includes a superabsorbent polymer, and wherein at least the superabsorbent polymer is biocompostable.

The disclosure pertains to hemostatic compositions comprising a plurality of nonwoven fibers disposed in a rapidly soluble solid matrix and methods of making and using the same. The compositions may also comprise one or more therapeutic agents.

The disclosure pertains to hemostatic compositions comprising a plurality of nonwoven fibers disposed in a rapidly soluble solid matrix and methods of making and using the same. The compositions may also comprise one or more therapeutic agents.

The resorbable preparation for medical use, and in particular for use as an resorbable dressing for difficult wounds, includes an amorphous hydrogel composed primarily of a mixture of animal collagen, glycerol, xylitol and ozonized vegetable oil in water.

The mixture may include, depending on the applications and methods of preparation: water, in proportion in the range of 10% to 90% by weight; either animal or synthetic collagen, in proportion in the range of 40% to 70% by weight; glycerol, in proportion in the range of 20% to 50% by weight; xylitol, in proportion in the range of 0.05% to 5% by weight; ozonized vegetable oil, in a proportion ranging between 0.001% and 10% by weight; lactoferrin, in proportion in the range of 0.001% to 10% by weight;

The proportion of water is defined as a function of the desired consistency for the resorbable preparation.