Biocompatible coatings and spin finishes that can be applied to polyhydroxyalkanoate (PHA) polymers, and medical devices made from PHA polymers, have been developed. The coatings impart good lubricity to PHA polymers, particularly to fibers and braids made from these materials, making the coatings ideal for use on medical devices such as PHA braided sutures. The spin finishes can be applied to PHA fibers to facilitate their manufacture, and also for their conversion to other products, including medical textiles. The spin finishes serve to protect multifilament fiber bundles, and keep them intact following extrusion, and also to impart lubricity to the fiber bundles and monofilament fibers so that they are not damaged in subsequent processing steps particularly in textile processing. The coating reduces tissue drag of, for example, braided sutures.

Resorbable implants, coverings and receptacles comprising poly(butylene succinate) and copolymers thereof have been developed. The implants are preferably sterilized, and contain less than 20 endotoxin units per device as determined by the limulus amebocyte lysate (LAL) assay, and are particularly suitable for use in procedures where prolonged strength retention is necessary, and can include one or more bioactive agents. The implants may be made from fibers and meshes of poly(butylene succinate) and copolymers thereof, or by 3d printing molding, pultrusion or other melt or solvent processing method. The implants, or the fibers preset therein, may be oriented. These coverings and receptacles may be used to hold, or partially/fully cover, devices such as pacemakers and neurostimulators. The coverings, receptacles and implants described herein, may be made from meshes, webs, lattices, non-wovens, films, fibers, foams, molded, pultruded, machined and 3D printed forms.

A staple cartridge assembly for use with a surgical stapling instrument is disclosed. The staple cartridge assembly comprises a compressible adjunct and a staple cartridge. The compressible adjunct comprises attachment regions. The staple cartridge comprises a proximal end, a distal end, a deck, a longitudinal row of staple cavities, staples, bonding zones, and barbs. The attachment regions of the compressible adjunct are configured to be secured to bonding areas defined by the bonding zones. The barbs protrude from the deck, and the barbs are configured to maintain an initial alignment between the attachment regions and the bonding zones prior to attachment of the compressible adjunct to the deck.

A surgical suture provides a visual indication when the suture is subjected to excessive tension. The suture has an inner core at least partially covered by a segmented outer layer. The inner core is not visible when the suture is subjected to acceptable amounts of tension, but will become visible if the suture is subjected to unacceptable amounts of tension. The visibility of the inner core thus indicates to the surgeon or similar medical professional whether or not the suture is under acceptable tension.

A staple cartridge assembly for use with a surgical stapling instrument includes a staple cartridge including a plurality of staples and a cartridge deck. The staple cartridge assembly also includes a compressible adjunct positionable against the cartridge deck, wherein the staples are deployable into tissue captured against the compressible adjunct, and wherein the compressible adjunct comprises a first biocompatible layer comprising a first portion, a second biocompatible layer comprising a second portion, and crossed spacer fibers extending between the first portion and the second portion.

The purpose of the present invention is to provide a low-profile stent graft which has a Type-III endoleak suppression effect, avoiding the problem with a stent graft which uses an extra-thin graft incurring enlarged needle holes or needle hole parts in a suture part. A stent graft according to the present invention comprises a proximate end, a distal end, and a lumen which is positioned between the proximate end and the distal end. The stent graft is formed by coupling a cylindrical graft to a stent with a suture. The cylindrical graft is formed from a fabric having a thickness of 10-90 m. The elastic modulus of the suture is 40 cN/dtex or less.

Novel absorbable, semi-crystalline, polymer blend compositions are disclosed exhibiting enhanced crystallization and nucleation rates. Also disclosed are medical device constructs, such as fibers made from such blends. The blends have a first absorbable polymeric component having a first molecular weight distribution and a second absorbable polymeric component which has an ultrahigh molecular weight distribution. The first and second polymeric components may be the same polymer.

Medical grade yarns, medical devices constructed of such yarns, and methods for making such yarns and devices are described. Polyester drawn fibers, and more particularly high strength and high tenacity micro polyester fibers for use in medical devices, and methods of preparing the same are provided.

Absorbable composite medical devices such as surgical meshes and braided sutures, which display two or more absorption/biodegradation and breaking strength retention profiles and exhibit unique properties in different clinical settings, are made using combinations of at least two types of yarns having distinctly different physicochemical and biological properties and incorporate in the subject construct special designs to provide a range of unique properties as clinically useful implants.

A novel high tensile strength semi-absorbable composite suture with minimized non-absorbable mass. The suture has a core made from a bioabsorbable polymer. The core is covered by a braided sheath. The braided sheath is made from an absorbable yarn and a bioabsorbable yarn. The bioabsorbable yarn is made from a least one filament of a bioabsorbable polymer. The nonabsorbable yarn is made from at least one filament of ultra high molecular weight polyethylene.