Patent classifications
A61L17/12
ELECTROSPUN BIOCOMPATIBLE FIBER COMPOSITIONS
A composition comprising a plurality of electrospun fiber fragments comprising at least one polymer, a plurality of electrospun fiber fragment clusters comprising at least one polymer, and, optionally, a carrier medium, is disclosed. Also disclosed is a kit comprising a first component of a plurality of electrospun fiber fragments, and a second component of a carrier medium. Also disclosed is a composition comprising a plurality of micronized electrospun fiber fragments, a carrier medium, and, optionally, a plurality of cells. Also disclosed is a biocompatible textile comprising a plurality of micronized electrospun fiber fragments. Also disclosed is a biocompatible suture comprising at least one electrospun fiber. Also disclosed is a method for making a biocompatible suture, comprising electrospinning a polymer solution onto a receiving surface, forming one or more non-overlapping nanofiber threads, removing the nanofiber threads from the receiving surface, and cutting the nanofiber threads into one or more biocompatible sutures.
Biological chord repair system and methods
An embodiment includes a chordal replacement system comprising: a pledget coupled to a first suture length and at least one of a first needle and a first ferrule; a second suture length coupled to the pledget and at least a second needle; and a third suture length coupled to the pledget and at least a third needle; wherein the second and third suture lengths are not monolithic with each other and do not constitute a single suture. Other embodiments are described herein.
Biological chord repair system and methods
An embodiment includes a chordal replacement system comprising: a pledget coupled to a first suture length and at least one of a first needle and a first ferrule; a second suture length coupled to the pledget and at least a second needle; and a third suture length coupled to the pledget and at least a third needle; wherein the second and third suture lengths are not monolithic with each other and do not constitute a single suture. Other embodiments are described herein.
Modified biodegradable and medical polymer devices and a method for preparing the same
A medical polymer device comprising a biodegradable polymer is provided, wherein the biodegradable polymer has a crystallinity of about 10% to about 80%, and preferably from about 20% to about 60%, wherein the medical polymer device comprises a small molecule organic compound which diffuses into the biodegradable polymer, the small molecule organic compound has a molecular weight of from about 100 to about 1000 Daltons, preferably from about 150 to about 500 Daltons, and more preferably from about 150 to about 250 Daltons, and the small molecule organic compound is non-evaporating or low-evaporating. The present invention also provides a method for preparing a medical polymer device according to the present invention as well as a method for modifying a medical polymer device made from a biodegradable polymer.
Modified biodegradable and medical polymer devices and a method for preparing the same
A medical polymer device comprising a biodegradable polymer is provided, wherein the biodegradable polymer has a crystallinity of about 10% to about 80%, and preferably from about 20% to about 60%, wherein the medical polymer device comprises a small molecule organic compound which diffuses into the biodegradable polymer, the small molecule organic compound has a molecular weight of from about 100 to about 1000 Daltons, preferably from about 150 to about 500 Daltons, and more preferably from about 150 to about 250 Daltons, and the small molecule organic compound is non-evaporating or low-evaporating. The present invention also provides a method for preparing a medical polymer device according to the present invention as well as a method for modifying a medical polymer device made from a biodegradable polymer.
Modified biodegradable and medical polymer devices and a method for preparing the same
A medical polymer device comprising a biodegradable polymer is provided, wherein the biodegradable polymer has a crystallinity of about 10% to about 80%, and preferably from about 20% to about 60%, wherein the medical polymer device comprises a small molecule organic compound which diffuses into the biodegradable polymer, the small molecule organic compound has a molecular weight of from about 100 to about 1000 Daltons, preferably from about 150 to about 500 Daltons, and more preferably from about 150 to about 250 Daltons, and the small molecule organic compound is non-evaporating or low-evaporating. The present invention also provides a method for preparing a medical polymer device according to the present invention as well as a method for modifying a medical polymer device made from a biodegradable polymer.
Absorbable iron-based device
An absorbable iron-based device includes an iron-based matrix and degradable polyester in contact with the surface of the iron-based matrix. The mass fraction of a low-molecular-weight part of the degradable polyester is less than or equal to 5%, and the molecular weight of the low-molecular-weight part is less than 10,000; or the mass fraction of a residual monomer in the degradable polyester is less than or equal to 2%.
Absorbable iron-based device
An absorbable iron-based device includes an iron-based matrix and degradable polyester in contact with the surface of the iron-based matrix. The mass fraction of a low-molecular-weight part of the degradable polyester is less than or equal to 5%, and the molecular weight of the low-molecular-weight part is less than 10,000; or the mass fraction of a residual monomer in the degradable polyester is less than or equal to 2%.
COMPOSITE SURGICAL SUTURE MATERIAL BASED ON POLYFILAMENTOUS TITANIUM THREAD AND BIORESORBABLE POLYMERS
In the field of medicine and medical technology, improving the technical properties of the surgical suture material. Composite surgical suture material includes titanium monothreads combined in a polyfilament thread, wherein a bioresorbable polymer material is present in the gaps between the monothreads and on their surface, and the monothreads have a relief surface. The technical result increases the strength, elasticity and plasticity of the suture material, the absence of a sawing effect on tissues, an increase in the sliding friction coefficient, and also in ensuring capability of carrying antibacterial and other medicinal substances in its structure, in ensuring a long-term presence in the body and possessing a high biological inertness in the late postoperative period, which excludes the initiation and persistence of aseptic inflammation associated with the presence of the material in the body.
COMPOSITE SURGICAL SUTURE MATERIAL BASED ON POLYFILAMENTOUS TITANIUM THREAD AND BIORESORBABLE POLYMERS
In the field of medicine and medical technology, improving the technical properties of the surgical suture material. Composite surgical suture material includes titanium monothreads combined in a polyfilament thread, wherein a bioresorbable polymer material is present in the gaps between the monothreads and on their surface, and the monothreads have a relief surface. The technical result increases the strength, elasticity and plasticity of the suture material, the absence of a sawing effect on tissues, an increase in the sliding friction coefficient, and also in ensuring capability of carrying antibacterial and other medicinal substances in its structure, in ensuring a long-term presence in the body and possessing a high biological inertness in the late postoperative period, which excludes the initiation and persistence of aseptic inflammation associated with the presence of the material in the body.