A composite medical textile such as a suture includes a plurality of bioresorbable hyaluronan-based fibers and a plurality of non-resorbable fibers. The hyaluronan-based fibers can include at least one of hyaluronic acid, sodium hyaluronate, or the esters of hyaluronic acid such as the benzyl esters. The non-resorbable fibers can be Ultra High Molecular Weight Polyethylene (UHMWPE), and other materials. Methods of making a medical textile are also disclosed.

A composite medical textile such as a suture includes a plurality of bioresorbable hyaluronan-based fibers and a plurality of non-resorbable fibers. The hyaluronan-based fibers can include at least one of hyaluronic acid, sodium hyaluronate, or the esters of hyaluronic acid such as the benzyl esters. The non-resorbable fibers can be Ultra High Molecular Weight Polyethylene (UHMWPE), and other materials. Methods of making a medical textile are also disclosed.

Provided are a suture, a suturing apparatus and applications thereof. The suture includes an elongated body, a first cam assembly and a second cam assembly both sleeved on the elongated body. The elongated body includes a first free end and a second free end. The first cam assembly and the second cam assembly each include at least one cam. The small end of the cam of the first cam assembly faces the first free end of the elongated body and the small end of the cam of the second cam assembly faces the second free end of the elongated body. A cross-sectional area of the small end of the cam is less than a cross-sectional area of the large end of the cam. A wall thickness of the cam tapers along a direction from the small end to the large end.

Provided are a suture, a suturing apparatus and applications thereof. The suture includes an elongated body, a first cam assembly and a second cam assembly both sleeved on the elongated body. The elongated body includes a first free end and a second free end. The first cam assembly and the second cam assembly each include at least one cam. The small end of the cam of the first cam assembly faces the first free end of the elongated body and the small end of the cam of the second cam assembly faces the second free end of the elongated body. A cross-sectional area of the small end of the cam is less than a cross-sectional area of the large end of the cam. A wall thickness of the cam tapers along a direction from the small end to the large end.

The present invention provides a medical molded article including a bioabsorbable polyester and having excellent followability to a living body, and the present invention is a medical molded article including a bioabsorbable polyester, the medical molded article having an amount-of-work-holding rate of 55% or more, the amount-of-work-holding rate defined as a rate of an amount of work generated finally by an operation that is repeated 10 times to an amount of work generated first by the operation, the operation in which a tensile stress is applied to the medical molded article in a direction of a maximum length of the medical molded article to generate a tensile strain of 100% with respect to an initial length.

The present invention provides a medical molded article including a bioabsorbable polyester and having excellent followability to a living body, and the present invention is a medical molded article including a bioabsorbable polyester, the medical molded article having an amount-of-work-holding rate of 55% or more, the amount-of-work-holding rate defined as a rate of an amount of work generated finally by an operation that is repeated 10 times to an amount of work generated first by the operation, the operation in which a tensile stress is applied to the medical molded article in a direction of a maximum length of the medical molded article to generate a tensile strain of 100% with respect to an initial length.

A braided barbed suture includes a barbed monofilament insert including an elongated core having a thickness and a plurality of barbs projecting outwardly from opposite sides of the elongated core. The braided barbed suture includes a braided sheath surrounding the elongated core to form a composite core of the braided barbed suture. The composite core has a thickness and the elongated core is located in a center of the composite core. The elongated core thickness is about 6-8 mil and the composite core thickness is about 13-18 mil. A ratio of the elongated core thickness relative to the composite core thickness is between about 0.16 to 0.91. The elongated core has transition zones that form a concave profile. The braided barbed suture has a single breaking point for both the braided sheath and the barbed monofilament insert. The barbed monofilament insert has a PDS monofilament core, and the braided sheath is a VICRYL multifilament yarn braided sheath.

Resorbable implants comprising poly(butylene succinate) and copolymers thereof have been developed. The implants are preferably sterilized, and contain less than 20 endotoxin units per device as determined by the limulus amebocyte lysate (LAL) assay, and are particularly suitable for use in procedures where prolonged strength retention is necessary, and can include one or more bioactive agents. The implants may be made from fibers and meshes of poly(butylene succinate) and copolymers thereof, or by 3d printing, and the fibers may be oriented. Coverings and receptacles made from forms of poly(butylene succinate) and copolymers thereof have also been developed for use with cardiac rhythm management devices and other implantable devices. These coverings and receptacles may be used to hold, or partially/fully cover, devices such as pacemakers and neurostimulators. The coverings and receptacles are made from meshes, webs, lattices, non-wovens, films, fibers, and foams, and contain antibiotics such as rifampin and minocycline.

Resorbable implants comprising poly(butylene succinate) and copolymers thereof have been developed. The implants are preferably sterilized, and contain less than 20 endotoxin units per device as determined by the limulus amebocyte lysate (LAL) assay, and are particularly suitable for use in procedures where prolonged strength retention is necessary, and can include one or more bioactive agents. The implants may be made from fibers and meshes of poly(butylene succinate) and copolymers thereof, or by 3d printing, and the fibers may be oriented. Coverings and receptacles made from forms of poly(butylene succinate) and copolymers thereof have also been developed for use with cardiac rhythm management devices and other implantable devices. These coverings and receptacles may be used to hold, or partially/fully cover, devices such as pacemakers and neurostimulators. The coverings and receptacles are made from meshes, webs, lattices, non-wovens, films, fibers, and foams, and contain antibiotics such as rifampin and minocycline.

The present invention is directed to a length adaptive surgical suture comprising a monofilament or a braid of a plurality of filaments, the suture having an original length when implanted and a second length that is different from the original length within a first twenty-four (24) hour period of time after implantation to accommodate tissue swelling. The present invention is also directed to configurations and combinations that enable length adaptive results.