Systems, apparatus, and methods are disclosed for conveying signals between a patient and monitoring and treatment devices. An EP system provides large-signal input protection and RF ablation signal noise suppression while preserving the integrity of relevant components of small signals. The EP system has a low-noise amplifier topology with minimal hardware filtering. An input protection circuit shunts to ground signals with amplitude above an ablation voltage. An RF filter circuit linearly attenuates the signals between 300 kHz and 600 kHz. A low-frequency feedback circuit drives a common mode node of the RF filter circuit for additional attenuation. A signal amplification circuit amplifies the signals between 0.01 Hz and 1000 Hz. A fast recovery circuit feeds back a low-frequency voltage signal to the signal amplification circuit to gradually reduce offset voltage of the signals. A high-resolution A/D converter converts the signals from the signal amplification circuit to clean digital signals.

Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.

Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.

An equalizing circuit may include a first signal line, a second signal line, a first current source, a first switch, a second switch, a second current source, a third switch, and a fourth switch. The second signal line forms a differential pair with the first signal line. The first switch connects the first signal line and the first current source. The second switch connects the second signal line and the first current source. The third switch connects the first signal line and the second current source. The fourth switch connects the second signal line and the second current source.

An equalizing circuit may include a first signal line, a second signal line, a first current source, a first switch, a second switch, a second current source, a third switch, and a fourth switch. The second signal line forms a differential pair with the first signal line. The first switch connects the first signal line and the first current source. The second switch connects the second signal line and the first current source. The third switch connects the first signal line and the second current source. The fourth switch connects the second signal line and the second current source.

An equalizing circuit may include a first signal line, a second signal line, a first current source, a first switch, a second switch, a second current source, a third switch, and a fourth switch. The second signal line forms a differential pair with the first signal line. The first switch connects the first signal line and the first current source. The second switch connects the second signal line and the first current source. The third switch connects the first signal line and the second current source. The fourth switch connects the second signal line and the second current source.

An equalizing circuit may include a first signal line, a second signal line, a first current source, a first switch, a second switch, a second current source, a third switch, and a fourth switch. The second signal line forms a differential pair with the first signal line. The first switch connects the first signal line and the first current source. The second switch connects the second signal line and the first current source. The third switch connects the first signal line and the second current source. The fourth switch connects the second signal line and the second current source.

Systems, apparatus, and methods are disclosed for processing biomedical signals. An electrophysiology (EP) system includes a differential circuit to process the biomedical signals; a differential amplifier circuit to amplify an output of the differential circuit; an analog-to-digital converter to digitize an output of the differential amplifier circuit; a communication module to interface between the analog-to-digital converter and a digital processing stage having a plurality of signal modules; and at least one processor to execute the plurality of signal modules, applying digital signal processing to the output from the analog-to-digital converter, to extract features of interest of the biomedical signals.

Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The embodiment further includes a communications interface communicatively coupled to a remote device, and a processor, coupled to the ECG circuit board, the plurality of IC circuit boards, and the communications interface. The processor is configured to receive, via the communications interface, feedback from the remote device. The processor is further configured to control, via the communication interface, the remote device based on the ECG signal, the IC signals, or the feedback from the remote device.

Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The ECG circuit board and the plurality of IC circuit boards share substantially a same circuit configuration and components. The ECG circuit board further processes the ECG signal using substantially a same path as each IC circuit board uses to process its corresponding IC signal.