A method for controlling generation of biologically desirable voids in a composition placed in proximity to bone or other tissue in a patient by selecting at least one water-soluble inorganic material having a desired particle size and solubility, and mixing the water-soluble inorganic material with at least one poorly-water-soluble or biodegradable matrix material. The matrix material, after it is mixed with the water-soluble inorganic material, is placed into the patient in proximity to tissue so that the water-soluble inorganic material dissolves at a predetermined rate to generate biologically desirable voids in the matrix material into which bone or other tissue can then grow.

A radiopaque composition with low viscosity and increased photopolymerizability for application or filling of hollow structures is disclosed. Moreover, a method to apply and monitor the application and/or the photopolymerization of the composition are presented.

Provided herein are methods for treating, adhering, or sealing biological tissue with a material, such as a hydrogel, that may include phyllosilicate nanoplatelets. The phyllosilicate nanoplatelets can have a high aspect ratio, a low aspect ratio, or be a mixture of high aspect ratio and low aspect ratio nanoplatelets. Drug releasing compositions and kits also are provided herein.

The present invention provides a bone cement composition. The bone cement composition includes a developing particle, an acrylic polymer, and an acrylic monomer, wherein a specific surface area of the developing particle is in a range from about 0.1 m.sup.2/g to about 5 m.sup.2/g. The present invention further provides a bone cement composition kit. The bone cement composition kit includes a power component and a liquid component, respectively stored in separate containers, wherein the power component includes a developing particle and an acrylic polymer, and the liquid component includes an acrylic monomer. A specific surface area of the developing particle is in a range from about 0.1 m.sup.2/g to about 5 m.sup.2/g.

The present invention provides a bone cement composition. The bone cement composition includes a developing particle, an acrylic polymer, and an acrylic monomer, wherein a specific surface area of the developing particle is in a range from about 0.1 m.sup.2/g to about 5 m.sup.2/g. The present invention further provides a bone cement composition kit. The bone cement composition kit includes a power component and a liquid component, respectively stored in separate containers, wherein the power component includes a developing particle and an acrylic polymer, and the liquid component includes an acrylic monomer. A specific surface area of the developing particle is in a range from about 0.1 m.sup.2/g to about 5 m.sup.2/g.

The present invention relates to an adhesive for a stoma and an adhesive tape for a stoma comprising the same. Specifically, the present invention relates to: an adhesive for a stoma, which can be attached to an affected part, having high adhesion, and has improved functionality for easy detachment from the skin; and an adhesive tape for a stoma comprising the same.

Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.

Disclosed herein are methods of connecting disrupted tissue, tissue repair, treating colorectal disorder and tissue welding. The methods comprise using a bioadhesive composition comprising ELP and light absorbing chromophores and irradiating the bioadhesive tissue.

Disclosed herein are methods of connecting disrupted tissue, tissue repair, treating colorectal disorder and tissue welding. The methods comprise using a bioadhesive composition comprising ELP and light absorbing chromophores and irradiating the bioadhesive tissue.

An adhesive wafer (10) for an ostomy device, the wafer comprising a skin-facing adhesive layer (40), a backing layer (30) on the non-skin-facing side of the adhesive layer, and a hole (60) for accommodating a stoma. On the central portion of the backing layer is located a release layer (110) being configured to release a neutralizer. The neutralizer is capable of neutralizing or at least minimizing the level of skin or adhesive aggressiveness of the output.