The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation enhancement element for implantation across the valve; a system including the coaptation enhancement element and anchors for implantation; a system including the coaptation enhancement element, catheter and driver; and a method for transcatheter implantation of a coaptation element across a heart valve.

An implantable apparatus, including at least one corrodible zinc-containing portion, where a content range of zinc in the at least one zinc-containing portion is [30, 50) wt. % and zinc in the zinc-containing portion is an amorphous structure, or a content range of zinc in the at least one zinc-containing portion is [50, 70] wt. %, and a microscopic structure of zinc in the zinc-containing portion is at least one of an amorphous structure, a non-equiaxed structure, an ultrafine-grained structure, or an equiaxed structure with a grain size number of 7 to 14, or a content range of zinc in the at least one zinc-containing portion is (70, 100] wt. % and a microscopic structure of zinc in the zinc-containing portion is at least one of a non-equiaxed structure, an ultrafine-grained structure, or an equiaxed structure with a grain size number of 7 to 14.

The present invention proposes an implant coating and drying device, including a chip sorter, a slide maker, a coating pool, a tablet pipe, a tablet conveying device, and a drying device. The chip sorter is connected to the slide maker, the shape of the coating pool is a circular arc. The coating pool is filled with coating solution. The inlet of the tablet pipe is connected with the slide maker, and the outlet of the tablet pipe is connected with the drying device, the tablet conveying device is used to deliver the implant tablet within the tablet pipe. The present invention proposes an implant coating and drying device, which has the advantages of simple structure and convenient operation, and avoids the defect of the prior art that the implant tablets adhere to each other, the coating is damaged, and the release degree of the implant tablet cannot be stabilized. The present invention proposes the implant coating and drying device is suitable for mass production.

The present invention relates to a slowly degraded alloy and a method for producing the same. The slowly degraded alloy comprises a degradable metal and a cladding layer. The degradable metal is completely covered with the cladding layer, such that a degradation rate of the degradable metal is decreased. Furthermore, because the cladding layer is made from polymer materials, the cladding layer does not be broken easily when a stress is applied to the slowly degraded alloy, thereby efficiently covering the degradable metal therein, and lowering the degradation rate of the degradable metal.

Embodiments of the present disclosure provide for structures including bioresorbable alloy membrane (e.g., Mg-, Fe-, Zn-based alloy membranes that include calcium, strontium, and/or manganese), methods of guided bone regeneration, and the like. In an aspect, the membrane can be a periodontal mesh that is biodegradable, bioerodible, and biocompatible and has a life time (e.g., 1-4 months) in line with what is desired for such procedures.

Various examples are provided for magnetic particle imbedded nanofibrous membranes. In one example, among others, a nanofibrous membrane includes one or more electrospun nanofibers forming form a layer of nanofibers, and a plurality of magnetic nanoparticles embedded in the one or more electrospun nanofibers. In another example, a method includes generating one or more electrospun nanofibers including magnetic nanoparticles from one or more nozzles positioned over a substrate to form a magnetic nanofibrous layer, and affixing the magnetic nanofibrous layer to a support structure. In another example, a system includes a magnetic nanofibrous membrane affixed to a support structure, and a magnetic field generator configured to generate a magnetic field that passes through the magnetic nanofibrous membrane.

A bone graft composition comprising a calcium phosphate putty is provided. A method of repairing a bone defect in a patient by applying the bone graft composition is also provided.

Medical stent designs are disclosed. An example stent includes a tubular scaffold having a proximal end and a distal end. The tubular scaffold includes a first filament extending between the proximal end and the distal end, the first filament including a first biodegradable region positioned adjacent to a second biodegradable region. Further, the first biodegradable region includes a first biodegradable material, the first biodegradable material having a first rate of degradation. The second biodegradable region includes a second biodegradable material, the second biodegradable material having a second rate of degradation, wherein the first rate of degradation is different from the second rate of degradation.

Invasive surgical devices such as joint implants and surgical tools are provided with a coating of visible or near visible light stimulated TiO.sub.2 based photocatalysts. The coatings may comprise one or more layers of different TiO.sub.2 crystal phases and may incorporate metal nodules. The devices reduce the incidence of infection via antimicrobial and bactericidal surface properties. Related devices and methods for illumination, air purification, and packaging are disclosed that comprise a complete system for use of the devices in surgical procedures.

In a method for manufacturing a component containing an iron alloy material, a pulverulent pre-alloy is provided. The pre-alloy comprises, in wt. %, 0.01 to 1% C, 0.0.01 to 30% Mn, 6% Al, and 0.05 to 6.0% Si, the remainder being Fe and usual contaminants. The pulverulent pre-alloy is mixed with at least one of elementary Ag powder, elementary Au powder, elementary Pd powder and elementary Pt powder so as to produce a powder mixture containing 0.1 to 20% of at least one of Ag, Au, Pd and Pt. The powder mixture is applied onto a carrier (16) by means of a powder application device (14). Electromagnetic or particle radiation is selectively irradiated onto the powder mixture applied onto the carrier (16) by means of an irradiation device (18) so as to generate a component from the powder mixture by an additive layer construction method.