A61L27/047

Bone Implant with Porous Membrane and Method for Preparation Thereof

The present invention relates to a bone implant with a porous lithium tantalate membrane and a method for preparing the bone implant. The bone implant comprises: (1) a substrate; and (2) a porous membrane on the substrate, wherein the substrate is selected from the group consisting of a tantalum substrate, a niobium substrate, a tantalum-niobium alloy substrate and a titanium substrate, and wherein the porous membrane is selected from the group consisting of a porous lithium tantalate membrane, a porous lithium niobate membrane, a porous lithium tantalate-lithium niobate mixture membrane and a porous titanium oxide membrane. The bone implant of the present invention has one or more of the following beneficial effects: (1) The bone implant has excellent corrosion resistance; (2) the elasticity modulus of the bone implant can be adjusted according to process conditions so that it has higher biocompatibility with the elasticity modulus of a human or animal bone (such as an alveolar bone and a cranium); (3) the white color of the bone implant is close to the color of the bone itself and the bone implant has an aesthetic appearance; (4) the bone implant has excellent bacteriostatic properties.

Method for Manufacturing Colored Product and Mobile Phone shell

The present invention relates to a method for manufacturing a colored product, in particular a colored mobile phone shell, comprising the following steps: (1) providing a product substrate, preferably a shell substrate; and (2) surface-treating the product substrate, preferably shell substrate, by an anodic oxidation method and/or a molten salt electrochemical method, wherein the product substrate, preferably shell substrate, is made of materials selected from the group consisting of tantalum, niobium, a tantalum-niobium alloy, titanium and a titanium alloy. The present invention further relates to a colored product, in particular a colored mobile phone shell, manufactured by the above method, comprising: (1) a product substrate, preferably a shell substrate; and (2) an amorphous metal oxide layer and/or lithium-containing compound layer formed on the surface of the product substrate, preferably shell substrate, wherein the product substrate, preferably shell substrate, is made of materials selected from tantalum, niobium, a tantalum-niobium alloy, titanium and a titanium alloy.

SYNERGISTIC ANTIBACTERIAL ACTIVITY OF MEDIUM POLARITY OILS IN COMBINATION WITH ANTIBACTERIAL AGENTS ON BACTERIAL BIOFILMS
20230345938 · 2023-11-02 ·

The compositions of the present invention comprise at least one medium polarity oil and at least one antibacterial agent, the combination of which produces a synergistic antibacterial effect against bacterial biofilms. Methods are disclosed for the reduction of bacteria in and/or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms.

OXIDE LAYER-CONTAINING ZIRCONIUM-NIOBIUM ALLOY TIBIAL PLATEAU PROSTHESIS HAVING BONE TRABECULA AND PREPARATION METHOD
20230338615 · 2023-10-26 ·

The present disclosure discloses a tibial plateau prosthesis with trabeculae containing zirconium-niobium alloy on oxidation layer and a preparation method thereof. The preparation method uses zirconium niobium alloy powder as raw material, conducting a 3D printing for one-piece molding to obtain an intermediate product of the tibial plateau, performing hot isostatic pressing and cryogenic oxidation to obtain the tibial plateau prosthesis comprising a proximal trabecular layer and a distal trabecular layer; the pore size and porosity of the proximal trabecular layer are evenly arranged, and the distal trabecular layer are partitioned; the topological structure of the trabeculae of the tibial plateau prosthesis is gradiently distributed from three dimensions; the micro-strain in the 64 % - 72 % region of the finite element model of the tibial plateau bone tissue is between the minimum effective strain threshold and the supraphysiological strain threshold, which increases the mechanical adaptation of the prosthesis.

BIOACTIVE IMPLANT FOR THE RESTORATION OF THE CONDUCTIVITY OF BIOELECTRIC STIMULI IN THE CARDIAC TISSUE

This innovation discloses a bioactive and biocompatible implant that comprises a fibrillar membrane of an electrospun polymeric matrix, where the matrix features a structural reinforcement with gold nanoparticles that allows the propagation of bioelectrical activity of the cardiac tissue, restoring the conductivity of the bioelectrical stimuli, given the electroconductive capacity provided by its components.

Monolithic composite orthopedic implants and associated methods
11458228 · 2022-10-04 · ·

Implementations described herein provide for functionless monolithic composite implants and methods for manufacturing the same. The implant includes a monolithic composite body having a first region comprising a first metal alloy, a second region comprising a second metal alloy, and a transition region disposed between the first region and the second region formed from a bonded mixture of the first alloy and the second alloy. In one example, the transition region is a sintered mixture of the first alloy and the second alloy. In another example, the transition region is disposed at a region of minimum stress within the monolithic composite body under physiological loading conditions of the implant.

VASCULAR PROSTHESIS FOR LEAK PREVENTION DURING ENDOVASCULAR ANEURYSM REPAIR

An embodiment includes a process for treating an abdominal aortic aneurysm (AAA) endoleak with a shape memory polymer (SMP) foam device. First, a bifurcated stent graft is placed within the aneurysm while a micro guidewire is positioned within the aneurysm for future catheter access. Second, after placing the iliac graft extension, a catheter is introduced over wire to deliver embolic foams. Third, embolic foams expand and conform to the aneurysm wall. Fourth, embolic foams create a stable thrombus to prevent endoleak formation by isolating peripheral vessels from the aneurysm volume.

COMPOSITE MATERIAL, IMPLANT COMPRISING THEREOF, USE OF THE COMPOSITE MATERIAL AND METHODS FOR PREPARING THE COMPOSITE MATERIAL AND A MEDICAL DEVICE
20220296789 · 2022-09-22 ·

The present application provides biodegradable composite material comprising bioresorbable magnesium or magnesium alloy embedded in bioresorbable glass fiber reinforced polymer matrix, and a bioresorbable implant comprising the composite material. The present application also provides use of the composite material, and methods for preparing the composite material and a medical device of a part thereof.

NANO SCALE DECORATION OF SCAFFOLD-FREE MICROTISSUE USING FUNCTIONALISED GOLD NANOSTRUCTURES

A method for regeneration or repair of an infarcted myocardium including an infarcted region in an animal comprising injecting into the animal a composition including one or more gold nanostructures is disclosed.

Chemically strengthened bioactive glass-ceramics

A chemically strengthened bioactive glass-ceramic composition as defined herein. Also disclosed are methods of making and using the disclosed compositions.