A medical device and a method and process for at least partially forming a medical device, which medical device has improved physical properties.

Disclosed are compositions comprising collagen covalently bound to particles, wherein covalent bonds are formed between reactive groups of the collagen and reactive groups of the particles, and wherein the particles have an average particle diameter ranging from 20 to 1000 nanometers. Also disclosed are various methods that utilize the compositions.

A composition and medical implant made therefrom, the composition including a thick diffusion hardened zone, and preferably further including a ceramic layer. Also provided are orthopedic implants made from the composition, methods of making the composition, and methods of making orthopedic implants from the composition.

The subject invention is directed to devices and methods for producing devices for regulating blood flow in the venous system. In particular, the invention provides for artificial valves designed to regulate the flow of blood in human vessels, wherein such artificial valves include superior properties including fatigue resistance, biocompatibility, and ease of manufacture.

A composite material having a first phase includes an aluminum oxide proportion of at least 65% by volume and a second phase comprising a zirconium proportion of 10 to 35% by volume. The zirconium is present as zirconium oxide. The aluminum oxide is a ceramic matrix and the zirconium oxide is dispersed therein. From 90 to 99% of the zirconium oxide is present in the tetragonal phase. A chemical stabilizer for stabilizing the tetragonal phase of the zirconium oxide is also present. The total content of chemical stabilizer is <0.2 mol % relative to the zirconium oxide content.

A method of making an implantable prosthesis includes applying a gelling enhancer layer over an inner surface of a wall of a silicone shell having anterior and posterior walls surrounding an interior volume. The method includes filling the interior volume of the shell with a silicone gel and curing the silicone gel. The cured silicone gel that is located within a zone that is in the vicinity of the gelling enhancer layer has a higher level of cohesiveness than the cured silicone gel that is located outside the zone. The zone of the silicone gel having the higher level of cohesiveness has a thickness of 2-10 mm. The silicone gel located outside the zone has a first concentration level of a gelling enhancer and the silicone gel located within the zone has a second concentration level of the gelling enhancer that is 5%-300% greater than the first concentration level.

A geared continuously variable transmission (GCVT) is provided. The GCVT includes a first set of solar gears having a first solar gear and first plurality of connection components. Power enters the GCVT through the first set of solar gears. The GCVT includes a second set of solar gears having a second solar gear and second plurality of connection components. Power exits the GCVT through the second set of solar gears. Power is transmitted from the first set of solar gears to the second set of solar gears via the first plurality of connection components and the second plurality of connection components. The GCVT includes a hydraulic pump and a hydraulic motor connecting first component from the first plurality of connection components to second component from the second plurality of connection components and providing constant rotation ratio between the first component and the second component.

Shapeable porous metal implants and methods for use in various procedures are disclosed. The implants can comprise a shell according to some examples. According to one example, the method can include providing a sheet of highly porous metal material having a porosity of between 55% and 90%, and wrapping the sheet of highly porous metal material around at least a first bone of the patient. Further examples can form the sheet intra-operatively to a desired shape. In an example, the porous metal sheet can be formed of tantalum or tantalum alloys.

A medical device and a method and process for at least partially forming a medical device, which medical device has improved physical properties.

For the purpose of firmly fusing a low-cost osteosynthetic implant having high osteoconductivity with a bone in a short period of time after implanting without having to perform treatment to restore surface hydrophilicity, a osteosynthetic implant is provided with a substrate that is formed of magnesium or a magnesium alloy and a porous anodic oxide coating that is formed on a surface of the substrate, wherein the anodic oxide coating has an outer surface that, due to the sizes and distribution of pores that are formed when generating the anodic oxide coating by means of anodic oxidation treatment, structurally prevents water from entering the pores while maintaining the hydrophilicity thereof.