An article comprising a substrate and an anti-microbial coating, wherein the anti-microbial coating comprises at least one solvent-free black phosphorus flake.

An article comprising a substrate and an anti-microbial coating, wherein the anti-microbial coating comprises at least one solvent-free black phosphorus flake.

Provided herein is technology relating to lipid compositions containing bioactive fatty acids and particularly, but not exclusively, to compositions and methods related to the production and use of structured lipid compositions containing sciadonic and/or pinoleic acid alone or in combination with other bioactive fatty acids including, but not limited to, eicosapentaenoic acid, docosahexaenoic acid, conjugated linoleic acid, and non-β-oxidizable fatty acid analogues such as tetradecylthioacetic acid.

Provided herein is technology relating to lipid compositions containing bioactive fatty acids and particularly, but not exclusively, to compositions and methods related to the production and use of structured lipid compositions containing sciadonic and/or pinoleic acid alone or in combination with other bioactive fatty acids including, but not limited to, eicosapentaenoic acid, docosahexaenoic acid, conjugated linoleic acid, and non-β-oxidizable fatty acid analogues such as tetradecylthioacetic acid.

A medical implant for cartilage and/or bone repair at an articulating surface of a joint is provided. The implant includes a contoured implant body and at least one extending post. The implant body has an articulating surface configured to face the articulating part of the joint and a bone contact surface configured to face the bone structure of a joint, where the articulating and bone contact surfaces face mutually opposite directions and the bone contact surface is provided with the extending post. A cartilage contact surface connects the articulating and the bone contact surfaces and is configured to contact the cartilage surrounding the implant body in a joint. The articulating surface has a layer that is formed of titanium nitride (TiN) as the wear-resistant material. The cartilage contact surface has a coating that is formed of a material having chondrointegration properties.

A medical implant for cartilage and/or bone repair at an articulating surface of a joint is provided. The implant includes a contoured implant body and at least one extending post. The implant body has an articulating surface configured to face the articulating part of the joint and a bone contact surface configured to face the bone structure of a joint, where the articulating and bone contact surfaces face mutually opposite directions and the bone contact surface is provided with the extending post. A cartilage contact surface connects the articulating and the bone contact surfaces and is configured to contact the cartilage surrounding the implant body in a joint. The articulating surface has a layer that is formed of titanium nitride (TiN) as the wear-resistant material. The cartilage contact surface has a coating that is formed of a material having chondrointegration properties.

In the present disclosure, an artificial joint stem includes a base and a coating film located on the base. The base includes a first region, a second region, and a third region located in sequence. The coating film contains a calcium phosphate-based material and an antimicrobial material. The coating film is located across the first region and the second region, and the third region is exposed from the coating film. The surface of the coating film located in the first region has a larger surface roughness than the surface of the base in the third region.

In the present disclosure, an artificial joint stem includes a base and a coating film located on the base. The base includes a first region, a second region, and a third region located in sequence. The coating film contains a calcium phosphate-based material and an antimicrobial material. The coating film is located across the first region and the second region, and the third region is exposed from the coating film. The surface of the coating film located in the first region has a larger surface roughness than the surface of the base in the third region.

A method of coating a bone material in a container is provided. The method comprising adding the bone material to an opening of the container and sealing the opening of the container so that the bone material is disposed within an interior of the container; adding a liquid coating material to the interior of the container through an inlet of the container so as to coat at least a portion of the bone material with the liquid coating material; removing any excess coating material from the container from the interior through an outlet of the container; and removing the coated bone material from the container. A system of coating bone material under a sterilized environment is also provided.

In the present disclosure, an artificial joint stem includes a base having an outer surface including a rough surface, and a coating film disposed on the rough surface of the base and containing a calcium phosphate-based material and an antimicrobial agent. The rough surface includes an exposed region exposed from the coating film.