A bioremodelable encasement structure comprising a pouch formed from at least one sheet of bioremodelable material, the pouch including an internal region that is configured to receive a device therein, the bioremodelable material comprising mesothelial tissue.

Bioremodelable tissue prostheses having a vasculature that is infused with a biomaterial composition.

The present application provides a preparation method for a biological membrane, and a product and an application thereof. The preparation method for the biological membrane comprises the following steps: (1) treating animal cavity tissues by using a collagenase inhibitor; (2) removing a membrane layer which accounts for more than 40% of the total fat content of the animal cavity tissues; (3) using a first enzyme solution to treat a product obtained in step (2); (4) using an alkali solution to treat a product obtained in step (3); (5) using a decellularized solution to treat a product obtained in step (4); (6) using a degreasing fluid solution to treat a product obtained in step (5); (7) using a second enzyme solution to treat a product obtained in step (6); and (8) using supercritical carbon dioxide to clean a product obtained in step (7) to obtain a biological membrane. In the present application, the integrity of a multi-layer space structure, elastic fibers and a collagen network of the biological membrane can be reserved to a great extent, the mechanical strength is high, residues of organic matters and reagents in the product can be removed, and the tissue regeneration inducing effect of the product is better.

A self-expanding wire frame for a pre-configured compressible transcatheter prosthetic cardiovascular valve, a combined inner frame/outer frame support structure for a prosthetic valve, and methods for deploying such a valve for treatment of a patient in need thereof, are disclosed.

Methods of treating biological tissue with bioremodelable tissue prostheses having a vasculature that is infused with a biomaterial composition.

Bioremodelable tissue prostheses having a vasculature that is infused with a biomaterial composition.

A bioremodelable encasement structure comprising a pouch formed from at least one sheet of bioremodelable material, the pouch including an internal region that is configured to receive a device therein, the bioremodelable material comprising mesothelial tissue.

A prosthetic atrioventricular tissue valve comprising a continuous tubular member formed from a first biocompatible material, the tubular member having proximal and distal ends, and at least one valve leaflet formed therein, the distal end of the tubular member including cardiovascular structure engagement means for connecting the tubular member to a cardiovascular structure, the cardiovascular structure engagement means comprising a plurality of elongated members that extend distally from the distal end of the tubular member.

A pouch structure formed from extracellular matrix (ECM) derived from small intestine submucosa (SIS) that includes an internal region configured to receive a medical device therein. The pouch structure is configured to modulate inflammation of damaged biological tissue and induce cell and tissue proliferation, bioremodeling of the damaged biological tissue, and regeneration of tissue structures with site-specific structural and functional properties, when implanted in a subject.

A bioremodelable encasement structure comprising a pouch formed from at least one sheet of bioremodelable material, the pouch including an internal region that is configured to receive a device therein, the bioremodelable material comprising mesothelial tissue.