A functionalized polyurethane, meniscus prosthesis, the preparation method thereof, and the uses therefor are disclosed. The meniscus prosthesis is manufactured by using polyurethane as the base material and incorporating a self-healing chemical bond, the dynamic dimethylglyoxime-urethane group. Additionally, hyaluronic acid coated with adamantane structures is introduced onto the surface of the self-healing polyurethane elastomer, creating a supramolecular lubricating coating with stress response characteristics. This successfully mimics the dynamic self-healing ability and physiological cyclic lubrication mechanism of natural meniscus, offering a novel solution for the treatment of meniscus injuries and holding great potential value in clinical applications.

In one aspect, a method includes providing support material within which the structure is fabricated, depositing, into the support material, structure material to form the fabricated structure, and removing the support material to release the fabricated structure from the support material. The provided support material is stationary at an applied stress level below a threshold stress level and flows at an applied stress level at or above the threshold stress level during fabrication of the structure. The provided support material is configured to mechanically support at least a portion of the structure and to prevent deformation of the structure during the fabrication of the structure. The deposited structure material is suspended in the support material at a location where the structure material is deposited. The structure material comprises a fluid that transitions to a solid or semi-solid state after deposition of the structure material.

A scaffold composite, and a preparation method and use thereof are provided. The preparation method includes: mixing a graphene oxide (GO) dispersion and a polylactic acid (PLA) dispersion, and subjecting a resulting mixed solution to curing and melt extrusion in sequence to obtain a 3-dimensional (3D)-printable GO/PLA composite wire; subjecting the 3D-printable GO/PLA composite wire to 3D printing to obtain a scaffold; and annealing the scaffold to obtain the scaffold composite.