A three-dimensional, biocompatible scaffold precursor composition for room-temperature printing a bio-compatible polymer/hydroxyapatite composite scaffold includes a room-temperature slurry, comprising a mixture of a sold phase that includes a mixture of tetracalcium phosphate (TTCP; Ca.sub.4(PO.sub.4).sub.2O) and dicalcium phosphate anhydrous (DCPA; CaHPO.sub.4), and a liquid phase that includes a polymer in a solvent. The solvent may be Ethanol (EtOH) or Tetrahydrofuran (THF), and the polymer may be polyvinyl butyral (PVB), polycaprolactone (PCL), or poly lactic-co-glycolic acid (PLGA). The slurry is printed at room temperature in aqueous phosphate (NaH.sub.2PO.sub.4) bath, which works as hardening accelerator, forming the polymer/hydroxyapatite composite scaffold

A three-dimensional, biocompatible scaffold precursor composition for room-temperature printing a bio-compatible polymer/hydroxyapatite composite scaffold includes a room-temperature slurry, comprising a mixture of a sold phase that includes a mixture of tetracalcium phosphate (TTCP; Ca.sub.4(PO.sub.4).sub.2O) and dicalcium phosphate anhydrous (DCPA; CaHPO.sub.4), and a liquid phase that includes a polymer in a solvent. The solvent may be Ethanol (EtOH) or Tetrahydrofuran (THF), and the polymer may be polyvinyl butyral (PVB), polycaprolactone (PCL), or poly lactic-co-glycolic acid (PLGA). The slurry is printed at room temperature in aqueous phosphate (NaH.sub.2PO.sub.4) bath, which works as hardening accelerator, forming the polymer/hydroxyapatite composite scaffold

There are provided methods of producing a component incorporating a bioactive material. In one embodiment the method comprises: (a) using a screw extruder to mix a polymeric material (I) with a bioactive material (II) and melt the polymeric material (I); and (b) making a component by moulding; and wherein the polymeric material (I) is of a type which includes: (i) phenyl moieties; (ii) ketone moieties; and (iii) ether moieties. Also provided are components comprising a polymeric material and a bioactive material.

There are provided methods of producing a component incorporating a bioactive material. In one embodiment the method comprises: (a) using a screw extruder to mix a polymeric material (I) with a bioactive material (II) and melt the polymeric material (I); and (b) making a component by moulding; and wherein the polymeric material (I) is of a type which includes: (i) phenyl moieties; (ii) ketone moieties; and (iii) ether moieties. Also provided are components comprising a polymeric material and a bioactive material.

There are provided methods of producing a component incorporating a bioactive material. In one embodiment the method comprises: (a) using a screw extruder to mix a polymeric material (I) with a bioactive material (II) and melt the polymeric material (I); and (b) making a component by moulding; and wherein the polymeric material (I) is of a type which includes: (i) phenyl moieties; (ii) ketone moieties; and (iii) ether moieties. Also provided are components comprising a polymeric material and a bioactive material.

The present disclosure relates to compositions useful in synthetic bone graft applications. Particularly, the disclosure teaches moldable bone graft compositions, methods of making said compositions, and methods of utilizing the same.

The present disclosure relates to compositions useful in synthetic bone graft applications. Particularly, the disclosure teaches moldable bone graft compositions, methods of making said compositions, and methods of utilizing the same.

The present disclosure relates to compositions useful in synthetic bone graft applications. Particularly, the disclosure teaches moldable bone graft compositions, methods of making said compositions, and methods of utilizing the same.

Present invention relates to a novel composition administering pharma agents using a bi-phasic recruiting moiety.

Present invention relates to a novel composition administering pharma agents using a bi-phasic recruiting moiety.