The proposed solution solves a problem of designing a machine for producing molded composite parts that are homogeneously structured and the problem of finding a method for producing composite for implants. The essence of the design of the machine consists in that it has a portioning assembly, whereby above a mold form unit (14) there is a guiding unit (11) located opposite a dosing unit (6) and above the aforementioned guiding unit (11) there is a pressing assembly (20) slidingly mounted on a vertical frame (19) and which is equipped with at least one piston rod (25) with a rammer (27) at its end.

A preliminary molding is being performed by thoroughly filling a preform trough and then the matter is being pushed out of the preform trough in portions and then each portion is rammed separately until consistency containing less than 15% air is achieved.

Provided are an absorbable biomedical composite material and a preparation method therefor. The absorbable biomedical composite material comprises: substrate granules containing a calcium-phosphorus compound; an intermediate layer which is coated on the surface of each of the substrate granules and has a first glass transition temperature, the first glass transition temperature being not higher than normal human body temperature; and a polymer matrix which is formed on the outer surface of the intermediate layer and has a second glass transition temperature, the second glass transition being higher than the first glass transition temperature. The absorbable biomedical composite material has increased mechanical strength and also improved toughness.

Provided are an absorbable biomedical composite material and a preparation method therefor. The absorbable biomedical composite material comprises: substrate granules containing a calcium-phosphorus compound; an intermediate layer which is coated on the surface of each of the substrate granules and has a first glass transition temperature, the first glass transition temperature being not higher than normal human body temperature; and a polymer matrix which is formed on the outer surface of the intermediate layer and has a second glass transition temperature, the second glass transition being higher than the first glass transition temperature. The absorbable biomedical composite material has increased mechanical strength and also improved toughness.

Provided are an absorbable biomedical composite material and a preparation method therefor. The absorbable biomedical composite material comprises: substrate granules containing a calcium-phosphorus compound; an intermediate layer which is coated on the surface of each of the substrate granules and has a first glass transition temperature, the first glass transition temperature being not higher than normal human body temperature; and a polymer matrix which is formed on the outer surface of the intermediate layer and has a second glass transition temperature, the second glass transition being higher than the first glass transition temperature. The absorbable biomedical composite material has increased mechanical strength and also improved toughness.

A method of recovering progenitor cells from bone marrow aspirate. A bone void filler preparation container is provided. The bone void filler preparation container has an inlet port and an outlet port. A bone graft matrix having a particle size of between about 1,000 m and about 2,000 m is placed in the bone void filler preparation container. A bone marrow aspirate is passed through the bone void filler preparation container. Progenitor cells in the bone marrow aspirate are retained in the bone void filler preparation container. A selectivity ratio of the progenitor cells retained in the bone void filler preparation container to a total number of nucleated cells retained in the bone void filler preparation container is greater than about 3.

A method of recovering progenitor cells from bone marrow aspirate. A bone void filler preparation container is provided. The bone void filler preparation container has an inlet port and an outlet port. A bone graft matrix having a particle size of between about 1,000 m and about 2,000 m is placed in the bone void filler preparation container. A bone marrow aspirate is passed through the bone void filler preparation container. Progenitor cells in the bone marrow aspirate are retained in the bone void filler preparation container. A selectivity ratio of the progenitor cells retained in the bone void filler preparation container to a total number of nucleated cells retained in the bone void filler preparation container is greater than about 3.

The present invention relates to a monolithic multi-layered material having at least a first layer, from which anisotropic pores originate, and a second layer, in which the anisotropic pores continue. The present invention further relates to a monolithic medical material having at least a first layer, from which anisotropic pores originate, and a second layer, in which the anisotropic pores continue. The present invention further relates to a process for the production of a multi-layered material having anisotropic pores. It further relates to a multi-layered material which can be produced by the process according to the invention.

The present invention relates to a monolithic multi-layered material having at least a first layer, from which anisotropic pores originate, and a second layer, in which the anisotropic pores continue. The present invention further relates to a monolithic medical material having at least a first layer, from which anisotropic pores originate, and a second layer, in which the anisotropic pores continue. The present invention further relates to a process for the production of a multi-layered material having anisotropic pores. It further relates to a multi-layered material which can be produced by the process according to the invention.

The present invention relates to bone repair material of multivariant amino acid polymer-hydroxyapatite, supportive implants and preparation method. Said restorative material is made of multivariant amino acid polymers consisted with -aminocaproic acid and other -amino acids, together with constituents modified hydroxyapatite, in which the constituent modified hydroxyapatite uses calcium salt as modified constituents that can be accepted in medicine and has a more solubility compared with hydroxyapatite. Modified hydroxyapatite is constructed from said calcium salt and hydroxyapatite, with a mass ratio of (2-20):(98-80), and the content of modified hydroxyapatite is 10-70% based on the mass of said bone repair material; the content of -aminocaproic acid in multivariant amino acid polymers is 60-99% based on the total molar quantity of multivariant amino acid polymers.

The present invention relates to bone repair material of multivariant amino acid polymer-hydroxyapatite, supportive implants and preparation method. Said restorative material is made of multivariant amino acid polymers consisted with -aminocaproic acid and other -amino acids, together with constituents modified hydroxyapatite, in which the constituent modified hydroxyapatite uses calcium salt as modified constituents that can be accepted in medicine and has a more solubility compared with hydroxyapatite. Modified hydroxyapatite is constructed from said calcium salt and hydroxyapatite, with a mass ratio of (2-20):(98-80), and the content of modified hydroxyapatite is 10-70% based on the mass of said bone repair material; the content of -aminocaproic acid in multivariant amino acid polymers is 60-99% based on the total molar quantity of multivariant amino acid polymers.