A tissue engineering meniscal composite scaffold (100) and a preparation method thereof. The meniscal composite scaffold (100) includes: a scaffold (110), wherein the scaffold (110) is C-shaped and has a shape which is consistent with the original shape of the meniscus to be regenerated, the scaffold (110) comprises a plurality of first degradable polymer fibers (111) extending along the circumferential direction of the scaffold (110) and a plurality of second degradable polymer fibers (112) extending along the radial direction of the scaffold (110), and the first degradable polymer fibers (111) form a multilayer intersection with the second degradable polymer fibers (112) and thereby generating a frame structure having a plurality of first apertures; and a matrix material (120) composited inside the plurality of first apertures of the scaffold (110) to form a meniscal composite scaffold (100) having a plurality of second apertures.

A tissue engineering meniscal composite scaffold (100) and a preparation method thereof. The meniscal composite scaffold (100) includes: a scaffold (110), wherein the scaffold (110) is C-shaped and has a shape which is consistent with the original shape of the meniscus to be regenerated, the scaffold (110) comprises a plurality of first degradable polymer fibers (111) extending along the circumferential direction of the scaffold (110) and a plurality of second degradable polymer fibers (112) extending along the radial direction of the scaffold (110), and the first degradable polymer fibers (111) form a multilayer intersection with the second degradable polymer fibers (112) and thereby generating a frame structure having a plurality of first apertures; and a matrix material (120) composited inside the plurality of first apertures of the scaffold (110) to form a meniscal composite scaffold (100) having a plurality of second apertures.

A tissue engineering meniscal composite scaffold (100) and a preparation method thereof. The meniscal composite scaffold (100) includes: a scaffold (110), wherein the scaffold (110) is C-shaped and has a shape which is consistent with the original shape of the meniscus to be regenerated, the scaffold (110) comprises a plurality of first degradable polymer fibers (111) extending along the circumferential direction of the scaffold (110) and a plurality of second degradable polymer fibers (112) extending along the radial direction of the scaffold (110), and the first degradable polymer fibers (111) form a multilayer intersection with the second degradable polymer fibers (112) and thereby generating a frame structure having a plurality of first apertures; and a matrix material (120) composited inside the plurality of first apertures of the scaffold (110) to form a meniscal composite scaffold (100) having a plurality of second apertures.

Systems, instruments, methods, and compositions are described involving removing a portion of the epidermis within a donor site on a subject, and harvesting dermal plugs within the donor site. An injectable filler is formed by mincing the dermal plugs. The injectable filler is configured for injecting into a recipient site on the subject.

Systems, instruments, methods, and compositions are described involving removing a portion of the epidermis within a donor site on a subject, and harvesting dermal plugs within the donor site. An injectable filler is formed by mincing the dermal plugs. The injectable filler is configured for injecting into a recipient site on the subject.

Systems, instruments, methods, and compositions are described involving removing a portion of the epidermis within a donor site on a subject, and harvesting dermal plugs within the donor site. An injectable filler is formed by mincing the dermal plugs. The injectable filler is configured for injecting into a recipient site on the subject.

Compositions and methods for treating tissue are provided. The compositions may include tissue matrix derived from adipose tissue suitable for injection, small-volume implantation, or use as a soft-tissue regenerative material. Also provided are methods for producing such compositions.

Compositions and methods for treating tissue are provided. The compositions may include tissue matrix derived from adipose tissue suitable for injection, small-volume implantation, or use as a soft-tissue regenerative material. Also provided are methods for producing such compositions.

Compositions and methods for treating tissue are provided. The compositions may include tissue matrix derived from adipose tissue suitable for injection, small-volume implantation, or use as a soft-tissue regenerative material. Also provided are methods for producing such compositions.

A method of manufacturing a tissue expander for implanting into a body of a living subject can include mixing granules of a solute with an elastomer. The method can further include forming a matrix with the elastomer. The granules can be embedded within the elastomer. The elastomer can define boundaries of a plurality of chambers within the matrix. The method can further include curing the elastomer, such that the boundaries of the matrix are permeable to water at a temperature between a desired temperature range.