The present invention concerns a bio-resorbable prosthesis (1, 1) for organs with lumens, as blood vessels and the like, comprising at least one bio-absorbable material layer (2), intended to be arranged in contact with said lumen organ when said prosthesis (1, 1) is implanted, and at least one auxetic material layer (3), arranged in contact with said at least one bio-absorbable material layer (2). The present invention also concerns a method for the production of a bio-absorbable prosthesis (1, 1).

The present invention concerns a bio-resorbable prosthesis (1, 1) for organs with lumens, as blood vessels and the like, comprising at least one bio-absorbable material layer (2), intended to be arranged in contact with said lumen organ when said prosthesis (1, 1) is implanted, and at least one auxetic material layer (3), arranged in contact with said at least one bio-absorbable material layer (2). The present invention also concerns a method for the production of a bio-absorbable prosthesis (1, 1).

A composition, comprising a hydrogel matrix and microparticles within said matrix, said matrix comprising a cross-linkable protein and a cross-linking agent, wherein said cross-linking agent is able to cross-link said cross-linkable protein, wherein said microparticles comprise a drug.

A composition, comprising a hydrogel matrix and microparticles within said matrix, said matrix comprising a cross-linkable protein and a cross-linking agent, wherein said cross-linking agent is able to cross-link said cross-linkable protein, wherein said microparticles comprise a drug.

A composition, comprising a hydrogel matrix and microparticles within said matrix, said matrix comprising a cross-linkable protein and a cross-linking agent, wherein said cross-linking agent is able to cross-link said cross-linkable protein, wherein said microparticles comprise a drug.

A resorbable polymeric mesh implant whose implant configuration varies over time after implantation for use in breast reconstruction, wherein the resorbable polymeric mesh implant comprises at least a first material and a last-degraded material, wherein the last-degraded material is substantially degraded at a later point in time in the body than the first material. The modulus of elasticity of the last-degraded material is significantly lower than the modulus of elasticity of the first material. The last-degraded material has a modulus of elasticity that corresponds to an elongation of 18 to 32% when subjected to a tensile load of 16 N/cm. The resorbable polymeric mesh implant is tubular and configured to retain a breast implant.

A resorbable polymeric mesh implant whose implant configuration varies over time after implantation for use in breast reconstruction, wherein the resorbable polymeric mesh implant comprises at least a first material and a last-degraded material, wherein the last-degraded material is substantially degraded at a later point in time in the body than the first material. The modulus of elasticity of the last-degraded material is significantly lower than the modulus of elasticity of the first material. The last-degraded material has a modulus of elasticity that corresponds to an elongation of 18 to 32% when subjected to a tensile load of 16 N/cm. The resorbable polymeric mesh implant is tubular and configured to retain a breast implant.

Absorbable barrier composites are designed for modulated gas and water permeability depending on clinical use and are formed of at least two physicochemically distinct components, one of which is a film adjoined to a knitted mesh and/or electrostatically spun, non-woven fabric. Depending on the physicochemical properties of the barrier composite, it can be used in neurological and urinogenital surgical procedures as well as tissue engineering and/or as physical barriers to prevent adhesion formation following several types of surgical procedures.

Absorbable barrier composites are designed for modulated gas and water permeability depending on clinical use and are formed of at least two physicochemically distinct components, one of which is a film adjoined to a knitted mesh and/or electrostatically spun, non-woven fabric. Depending on the physicochemical properties of the barrier composite, it can be used in neurological and urinogenital surgical procedures as well as tissue engineering and/or as physical barriers to prevent adhesion formation following several types of surgical procedures.

A multilayered polymer composite film includes a water-soluble polymer matrix and a plurality of fibers embedded within the water soluble polymer matrix. The fibers include a water insoluble polymer material and at least one of a non-polymeric hydrophobic therapeutic agent or a non-polymeric hydrophobic cosmetic agent incorporated in the water insoluble polymer material. The fibers have a rectangular cross-section, and extend the entire length of the multilayered polymer composite film.