Porous hydrophilic composites for use in promoting bone growth are disclosed, along with methods for their preparation. The composites comprise a porous biodegradable polymer matrix, and nanosized calcium phosphate (CaP) homogeneously dispersed throughout the polymer matrix. The CaP has a specific surface area in the range of about 180 to about 380 m.sup.2/g.

Porous hydrophilic composites for use in promoting bone growth are disclosed, along with methods for their preparation. The composites comprise a porous biodegradable polymer matrix, and nanosized calcium phosphate (CaP) homogeneously dispersed throughout the polymer matrix. The CaP has a specific surface area in the range of about 180 to about 380 m.sup.2/g.

The present invention relates to methods for providing polymeric composites with bone forming, such as with osteogenic and/or osteoinductive and/or osteoconductive, properties. The present invention further relates to polymeric composites provided by the present method and the use of thereof for bone implants, or grafts, specifically the use thereof for orbital floor reconstruction. Specifically, the present invention relates to methods for providing a composite with bone forming properties, the method comprises the steps of: a) providing a liquid, or liquefied, polymeric composition of homopolymers or copolymers of 1,3-trimethylene carbonate (TMC); b) adding to said liquid, or liquefied, polymeric composition one or more agents with osteogenic and/or osteoinductive and/or osteoconductive properties thereby providing a dispersion of said agents in said liquid or liquefied polymeric composition; and c) crosslinking the product obtained, thereby providing a composite with bone forming properties.

The present invention relates to methods for providing polymeric composites with bone forming, such as with osteogenic and/or osteoinductive and/or osteoconductive, properties. The present invention further relates to polymeric composites provided by the present method and the use of thereof for bone implants, or grafts, specifically the use thereof for orbital floor reconstruction. Specifically, the present invention relates to methods for providing a composite with bone forming properties, the method comprises the steps of: a) providing a liquid, or liquefied, polymeric composition of homopolymers or copolymers of 1,3-trimethylene carbonate (TMC); b) adding to said liquid, or liquefied, polymeric composition one or more agents with osteogenic and/or osteoinductive and/or osteoconductive properties thereby providing a dispersion of said agents in said liquid or liquefied polymeric composition; and c) crosslinking the product obtained, thereby providing a composite with bone forming properties.

A bioactive filamentary structure includes a sheath coated with a mixture of synthetic bone graft particles and a polymer solution forming a scaffold structure. In forming such a structure, synthetic bone graft particles and a polymer solution are applied around a filamentary structure. A polymer is precipitated from the polymer solution such that the synthetic bone graft particles and the polymer coat the filamentary structure and the polymer is adhered to the synthetic bone graft particles to retain the graft particles.

A non-swivel suture anchor system to secure soft tissue to bone comprising a tip component which comprises a widened end portion and a shaft, and a cannulated screw.

A non-swivel suture anchor system to secure soft tissue to bone comprising a tip component which comprises a widened end portion and a shaft, and a cannulated screw.

A bioabsorbable surgical osteosynthesis plate operable to be secured by at least one fastener through at least one fastener opening formed in the plate to a bone. The plate includes a flat section having first and second surfaces defining a main plane of the plate. The plate includes a polymer material that is oriented multiaxially and is substantially rigid and substantially deformable at a first thermochemical state. In the multiaxially oriented structure of the plate the polymer material is arranged according to at least three different orientation axes along the main plane of the plate as a result of solid state drawing of the plate. The polymer material of the plate has isotropic mechanical tear properties in different directions along the main plane of the plate.

A bioabsorbable surgical osteosynthesis plate operable to be secured by at least one fastener through at least one fastener opening formed in the plate to a bone. The plate includes a flat section having first and second surfaces defining a main plane of the plate. The plate includes a polymer material that is oriented multiaxially and is substantially rigid and substantially deformable at a first thermochemical state. In the multiaxially oriented structure of the plate the polymer material is arranged according to at least three different orientation axes along the main plane of the plate as a result of solid state drawing of the plate. The polymer material of the plate has isotropic mechanical tear properties in different directions along the main plane of the plate.

A bioactive filamentary structure includes a sheath coated with a mixture of synthetic bone graft particles and a polymer solution forming a scaffold structure. In forming such a structure, synthetic bone graft particles and a polymer solution are applied around a filamentary structure. A polymer is precipitated from the polymer solution such that the synthetic bone graft particles and the polymer coat the filamentary structure and the polymer is adhered to the synthetic bone graft particles to retain the graft particles.