A prosthetic venous valve having a conical shaped base valve member and a biomaterial delivery construct. The base valve member includes a plurality of fluid flow modulating means that open and allow antegrade blood to be transmitted out of the valve member when the valve member receives antegrade blood therein, and close and prevent retrograde blood from flowing into the valve member. The biomaterial delivery construct is adapted to receive and position the base valve member therein, and be disposed proximate a luminal wall of a venous vessel.

Various embodiments related to systems, methods, and articles for rapid inactivation of SARS-CoV-2 by silicon nitride and aluminum nitride are disclosed herein.

Compositions including a complex of fatty acids (e.g., including one or more C4 to C40 fatty acids, such as a C4 to C20 fatty acid) and one or more amino acids (and particularly one or more amino acids having electrically charged basic side chains, e.g., Arginine, Lysine, etc.) for use as an anti-pathogenic composition. These compositions may include the complex of fatty acid:amino acid having a lamellar supramolecular structure. In particular, described herein are therapeutic compositions of undecylenic acid:Arginine forming a complex of undecylenic acid and Arginine.

Prosthetic valves that include conical shaped base valve members having an annular engagement end, a closed distal end region that restricts fluid flow therethrough, and a plurality of elongated ribbon members, which transition from an open fluid flow configuration to a closed fluid flow configuration in response to expansion and contraction of the base valve member, and a support structure that is configured and adapted to exert retaining forces on the annular engagement ends of the base valve members, whereby the support structure (i) conforms to the shape of the annular engagement ends of the base valve members, (ii) securely positions the annular engagement ends of the base valve members adjacent to and, thereby, in contact with a valve annulus, whereby the annular engagement ends of the base valve members conform to the shape of the valve annulus, and (iii) the annular engagement ends of the base valve members adapt to at least one fluctuation in the configuration and/or dimension of the valve annulus, whereby the annular engagement ends of the base valve members maintain contact therewith.

A prosthetic valve comprising a conical shaped sheet structure and a support structure, the sheet structure having a closed distal end and a plurality of elongated ribbon members that are positioned proximate each other in a joined relationship, whereby the ribbon members form a plurality of fluid flow modulating regions that close when fluid flow through the valve exhibits a negative flow pressure and open when fluid flow through the valve exhibits a positive flow pressure, the support structure having at least one elongated cardiovascular structure engagement member that is associated with one of the ribbon members and adapted to engage a cardiovascular structure.

Various embodiments related to systems, methods, and articles for rapid inactivation of SARS-CoV-2 by silicon nitride and aluminum nitride are disclosed herein.

A compression bandage is provided that includes a zinc oxide composition and/or one or more other therapeutic agents. In use, the bandage can be compression wrapped directly contacting a subjects skin for application of the zinc oxide composition and/or other therapeutic agents.

Disclosed herein are compositions to use in biofouling-resistant coatings, biofouling-resistant coatings, methods of making biofouling-resistant coatings, biofouling-resistant devices, and methods of making biofouling-resistant devices.

Compositions including a complex of fatty acids (e.g., including one or more C4 to C40 fatty acids, such as a C4 to C20 fatty acid) and one or more amino acids (and particularly one or more amino acids having electrically charged basic side chains, e.g., Arginine, Lysine, etc.) for use as an anti-pathogenic composition. In particular, described herein are compositions of decanoic acid:Arginine in which the decanoic acid and Arginine for a complex having a lamellar supramolecular structure.

A thermostable composition with antiviral and antimicrobial activity is used as a biologically active component for the production of sanitary and hygienic products, as well as for protection against bacterial and viral infections. In particular, the thermostable composition is a lyophilized powder containing the following components per 1 g of the composition: recombinant interferon gamma human with the activity from 500,000 to 2,000,000 IU/g 0.03 to 0.12 mg; lysostaphin with the activity from 50 to 200 U/g 0.17 to 0.68 mg; methoxy polyethylene glycol 30-150 mg; sodium alginate 10-25 mg; sodium dihydrophosphate dihydrate 120-250 mg; citric acid 35-110 mg and remaining dextran. The thermostable composition can be used as a component of oral hygiene products, toothpastes, sanitary and hygiene articles, a clothes conditioner and condom lubricant and in a number of medicinal products and drugs.