In a method for producing a cell concentrate using a cell suspension treatment system including a storage container of a cell suspension, which has a solution inlet port, a circulation outlet port, and a circulation inlet port, a cell suspension treatment device for concentrating the cell suspension by separating liquid from the cell suspension by filtration, the device including a container having a cell suspension introduction port, a cell suspension lead-out port, and a filtrate outlet, which is filled with a hollow fiber separation membrane, a circulation circuit for concentrating the cell suspension while circulating the cell suspension between the storage container and the cell suspension treatment device, a collection container of a cell concentrate obtained by concentration, a collection path for feeding the cell concentrate to the collection container, an injection path for injecting a solution into the solution inlet port of the storage container, and a detecting unit.

A blood sampling device (10) configuring a blood bag system (12) includes: a hollow needle (80) that can penetrate through a rubber plug (202) of a blood sampling tube (200) inserted into a blood sampling holder (78); a hub (76) that includes a needle supporting unit (90) for supporting a base end side of the hollow needle (80) and to which the blood sampling holder (78) is rotatably attached; a needle cover (82) made of rubber that is externally fitted to the needle supporting unit (90) while covering a tip side of the hollow needle (80); and a cap (84) arranged on the needle supporting unit (90) in such a manner that the cap (84) can come into contact with the needle cover (82) and is independent of the blood sampling holder (78).

A disposable bag set for separating discrete volumes of a composite fluid includes a separation bag including the composite fluid to be separated; a first bag in fluid communication with the separation bag, the first bag configured to receive a first component of the composite fluid from the separation bag; and a second bag in fluid communication with the first bag and not the separation bag, the second bag configured to receive a product formed using the first component.

In a blood transfusion system (a blood transfusion kit, a blood transfusion kit for emergency blood transfusion, or a method of using a blood transfusion kit), a flow path through which blood flows is formed using a tube having a channel therein. The flow path includes: a first path that connects an upstream path and a downstream path and has a leukocyte removal filter removing leukocytes at an intermediate position of the channel and a second path that connects the upstream path and the downstream path and bypasses the leukocyte removal filter.

A blood processing filter includes a container having 2 ports respectively functioning as an inlet for a liquid to be processed and as an outlet for the processed liquid, and a filtration medium filled in the container, wherein an airflow resistance of the filtration medium is 55.0 kPa.Math.s/m or more and less than 85.0 kPa.Math.s/m, the filtration medium includes a filter material A having an airflow resistance per unit basis weight of 0.01 kPa.Math.s.Math.m/g or more and less than 0.04 kPa.Math.s.Math.m/g and a filter material B having an airflow resistance per unit basis weight of 0.04 kPa.Math.s.Math.m/g or more, at least a part of the filter material A is disposed on a side closer to the inlet for a liquid to be processed than the filter material B, and a sum of airflow resistances of the filter material A is 6.0 kPa.Math.s/m or more.

Blood filters for enhanced leukoreduction with platelet recovery are disclosed. The filters include a non-woven, porous filter coated with an acetonic copolymer solution.

Medical containers and disposable fluid circuits (kits) including such containers are disclosed. The containers and kit components are made of a plastic composition including polyvinyl chloride and one or more plasticizers such as a citrate ester and an epoxidized vegetable oil are disclosed. Containers made from such compositions are useful in the storage red blood cells. Red blood cell products wherein the red blood cells exhibit a reduced level of hemolysis are also disclosed.

The disclosure provides for a container system and method for the cryopreservation and resuspension of a body fluid. The container system may include a cryopreservation container comprising the body fluid in a cryopreservation liquid, a resuspension container comprising a resuspension solution, a connection tube sterilely connecting the cryopreservation container and the resuspension container, and at least one shut-off element actively associated with the connection tube.

Methods of priming a plasma processing system are disclosed. The plasma processing system has a number of different fluid flow circuits that are defined by sources of fluid, fluid flow paths, waste containers, a mixer, a separator, valves and a pump. A first fluid circuit is flushed, where the first fluid circuit is defined by a source of a first fluid, a first valve positioned between the source of the first fluid and the first fluid flow path, a second valve positioned between the first fluid flow path and the second fluid flow path, a first pump positioned between the second fluid flow path and the third fluid flow path, and a first waste container in fluid communication with the third fluid flow path. A second fluid circuit is then flushed by closing and opening certain valves.

An object of the present invention is to provide a novel filter material and a filter including the same. Specifically, the present invention aims to provide a filter material capable of filtering in a short period of time, without clogging of the filter, while maintaining high cell separation properties, and a filter including the same. More specifically, the present invention aims to provide a filter material in which fiber masses (flocs) are uniformly distributed, and a filter including the same. The present invention provides a novel filter material showing excellent cell separation properties and excellent flow-through properties regardless of design choices for filters known prior to the filing of the present application, and an efficient cell separation method using a novel filter on which the filter material is stacked.