A spectroscopic detection system includes a sensor configured to reflect light of a first wavelength associated with a presence of a reference substance on the sensor and configured to reflect light of a second wavelength associated with a presence of a monitored substance on the sensor, wherein the monitored substance flows to the sensor from a circulating fluid. The spectroscopic detection system further includes a detector that has first and second channels for respectively receiving the light of the first and second wavelengths reflected from the sensor and one or more processors in electrical communication with the detector and configured to identify an excess condition of the monitored substance with respect to the circulating fluid based on a ratio of a second amount of the light of the second wavelength received at the detector to a first amount of the light of the first wavelength received at the detector.

The invention relates to a system for treating blood, which includes a single cassette capable of carrying out the various CRRT treatments.

A dialysis system is disclosed that enables a patient to undergo both peritoneal dialysis and extracorporeal blood treatments. The system includes a base unit and a blood treatment unit configured to perform extracorporeal blood treatments on a patient. The blood treatment unit includes a user interface operable with a controller for displaying a calendar of days in which an extracorporeal blood treatment is scheduled to be performed. The base unit includes a base unit controller that is programmed to receive information indicative whether a peritoneal dialysis treatment or the extracorporeal blood treatment is to be performed. The base unit controller operates first software instructions when the base unit uses a first fluid stored in a fluid container when the peritoneal dialysis treatment is selected or operates second software instructions when the base unit uses a second, different fluid from an online source when the extracorporeal blood treatment is selected.

Dialysis systems and methods for operating dialysis machines (e.g., peritoneal dialysis machines) for conducting dialysis treatments are disclosed. The dialysis system may include a dialysis machine for transferring dialysate to a patient from a dialysate source. The dialysate may flow from the dialysate source through a cassette (e.g., a disposable cassette) positionable within a port formed in the dialysis machine. The dialysis system may also include a cleaning cartridge insertable into the port. The cleaning cartridge may be arranged and configured to collect, remove, etc. any foreign material or debris from the port.

A system and method is provided for generating simulated dialysis treatment files. For instance, a computing device may obtain information such as general patient information, dialysis prescription information, and dialysis treatment information. The computing device may generate a dialysis treatment file based on the obtained information, and use the dialysis treatment file to verify and test an enterprise system. For instance, the generated dialysis treatment file may be used to ensure the enterprise system is functioning properly.

A peritoneal dialysis (“PD”) system includes a cycler having a micropump actuator, a pressure transducer, and at least one valve actuator; a disposable set including a micropump head sized and shaped for mating with and being driven by the micropump actuator, a pressure sensor configured to operably communicate with the pressure transducer, and at least one fluid valve portion or a portion of at least one fluid line for interfacing with the at least one valve actuator; and a control unit, wherein the disposable set may be arranged to allow, and the control unit may be programmed to operate the micropump actuator and the at least one valve actuator, so that fresh and used dialysis fluid flows through the micropump head in a same direction. The system may also dampen pressure fluctuations via pressure pods, and may analyze the outputs from the pressure pods for patient empty and occlusion detection.

A personalized chronic care system including (i) a sensor; (ii) a data receiving device separate from the sensor and configured to receive data directly or indirectly from the sensor; (iii) a data analytics device separate from the sensor and including at least one algorithm configured to analyze the sensor data and provide an analyzed data outcome; and (iv) at least one output device separate from the sensor and in communication with the data analytics device, the at least one output device configured to receive and communicate the analyzed data outcome to a health care provider.

A peritoneal dialysis system includes a cycler, a disposable set operable with the cycler and including a patient line and a drain line, one of (i) a water purifier for supplying purified water for mixing to form fresh dialysis fluid at the disposable set, (ii) at least one fresh dialysis fluid container provided as part of the disposable set for supplying fresh dialysis fluid, or (iii) a dialysis fluid preparation unit configured to supply fresh dialysis fluid to the disposable set, and at least one flow path insulator provided at the cycler, the water purifier, the dialysis fluid preparation unit, and/or along the drain line. The flow path insulator is configured to separate used dialysis fluid flowing along the drain line into flow segments to limit any current flowing from the patient to a drain.

Improvements in fluid volume measurement systems are disclosed for a pneumatically actuated diaphragm pump in general, and a peritoneal dialysis cycler using a pump cassette in particular. Pump fluid volume measurements are based on pressure measurements in a pump control chamber and a reference chamber in a two-chamber model, with different sections being modeled using a combination of adiabatic, isothermal and polytropic processes. Real time or instantaneous fluid flow measurements in a pump chamber of the diaphragm pump are also disclosed, in this case using a one-chamber ideal gas model and using a high speed processor to obtain and process pump control chamber pressures during fluid flow into or out of the pump chamber. Improved heater control circuitry is also disclosed, to provide added or redundant safety measures, or to reduce current leakage from a heater element during pulse width modulation control of the heater element. Improvements are also disclosed in an application of negative pressure during a drain phase in peritoneal dialysis therapy, and to control an amount of intraperitoneal fluid accumulation during the therapy. Improvements in efficiency are also disclosed in movement of fluid into and out of a two-pump cassette and a heater bag of the peritoneal dialysis cycler, and in synchronization of operation of two or more pumps in the peritoneal dialysis cycler or other fluid handling devices using a multi-pump arrangement.

A dialysis fluid apparatus includes a flexible dialysis fluid container, a holder structured such that the flexible dialysis fluid container is held vertically within the holder and conforms to a shape of the holder, a pressure sensor positioned and arranged to sense a pressure of a fluid held within the flexible dialysis fluid container, and a control unit configured to (i) store at least one cross-sectional area of the flexible dialysis fluid container, (ii) calculate a head height using the pressure of the fluid held within the flexible dialysis fluid container, and (iii) calculate a volume of the fluid held within the flexible dialysis fluid container using the cross-sectional area and the head height.