A sterilizable connector may include a sterilization fluid reservoir to provide a sterilization fluid. The sterilizable connector may include a connector. The connector may include a first end to receive a first tube to connect to a medical device (e.g., directly or via one or more intervening components). The connector may include a second end to receive a second tube to connect to a patient (e.g., directly or via one or more intervening components). The connector may include a body to couple the first end to the second end to enable fluid transfer between the first tube and the second tube. The connector may include a body opening to couple to the sterilization fluid reservoir. The sterilizable connector may include a sterilization fluid injector to inject the sterilization fluid from the sterilization fluid reservoir to the connector.

A medical fluid delivery machine includes a pump interface having an actuation area for delivering positive or negative pressure to a medical fluid handling device; a pressure sensor positioned to measure pressure within the actuation area; a valve positioned to selectively vent the actuation area to atmosphere; and a control unit in signal communication with the pressure sensor and control communication with the valve, the control unit performing a sequence during pumping, wherein (i) application of positive pressure or negative pressure to the actuation area is stopped, the valve is switched to vent the actuation area to atmosphere, then switched to close the actuation area to atmosphere, and at least one pressure signal reading is taken via the pressure sensor, and (ii) a determination is made whether positive pressure or negative pressure to the chamber should be resumed based on the at least one pressure signal reading.

A peritoneal dialysis device includes a disposable tubing set that includes a fill line with a patient access connector at one end and a dialysis fluid receiving end opposite the patient access connector end. The device also includes a fill-side pressure measuring sensor attached at the fill end and forming a disposable component of the tubing set and a patient-side pressure measuring sensor located at the fluid receiving end. The patient-side and fill-side pressure measuring sensors are adapted for measuring pressure in the fill line at the respective ends thereof. The device also includes a controller configured to regulate a rate of flow in the fill line responsively to a signal from the at least the patient-side pressure measuring sensor.

Dialysis is enhanced by using nanoclay sorbents to better absorb body wastes in a flow-through system. The nanoclay sorbents, using montmorillonite, bentonite, and other clays, absorb significantly more ammonium, phosphate, and creatinine, and the like, than conventional sorbents. The montmorillonite, the bentonite, and the other clays may be used in wearable systems, in which a dialysis fluid is circulated through a filter with the nanoclay sorbents. Waste products are absorbed by the montmorillonite, the bentonite, and the other clays and the dialysis fluid is recycled to a patient's peritoneum. Using an ion-exchange capability of the montmorillonite, the bentonite, and the other clays, waste ions in the dialysis fluid are replaced with desirable ions, such as calcium, magnesium, and bicarbonate. The nanoclay sorbents are also useful for refreshing a dialysis fluid used in hemodialysis and thus reducing a quantity of the dialysis fluid needed for the hemodialysis.

A urea separation apparatus is described herein. In an embodiment, the urea separation apparatus includes a blood compartment that is a part of an extracorporeal circuit fluidly connected to a patient and configured to receive blood of the patient. The apparatus also includes a waste membrane enclosing the blood compartment that is configured to filter waste from the blood. The apparatus further includes a dialysis fluid compartment located on an opposite side of the waste membrane from the blood compartment. The dialysis fluid compartment includes dialysis fluid that absorbs the waste from the waste membrane. The apparatus moreover includes a charged membrane enclosing the dialysis fluid compartment. The charged membrane is configured to filter at least a portion of the waste from the dialysis fluid. Additionally, the apparatus includes a urea compartment that circulates secondary fluid for absorbing the portion of the waste from the charged membrane.

A peritoneal dialysis system includes (i) a fill container, and (ii) an energizing unit that removably accepts the fill container, the energizing unit including a sterilization source so configured and arranged relative to the fill container when accepted by the energizing unit to place fluid within the fill container in a physiologically safe condition for delivery to the peritoneal cavity of a patient.

A dialysis system is disclosed that enables a patient to undergo both peritoneal dialysis and extracorporeal blood treatments. The system includes a base unit and a blood treatment unit configured to perform extracorporeal blood treatments on a patient. The blood treatment unit includes a user interface operable with a controller for displaying a calendar of days in which an extracorporeal blood treatment is scheduled to be performed. The base unit includes a base unit controller that is programmed to receive information indicative whether a peritoneal dialysis treatment or the extracorporeal blood treatment is to be performed. The base unit controller operates first software instructions when the base unit uses a first fluid stored in a fluid container when the peritoneal dialysis treatment is selected or operates second software instructions when the base unit uses a second, different fluid from an online source when the extracorporeal blood treatment is selected.

A computer-implemented medical system is provided. The system includes a docking station and a mobile machine. The system is configured to perform operations comprising: receiving, by the mobile machine and from a user, a request to transport the mobile machine to a target location to perform a medical treatment; automatically navigating the mobile machine to the target location; performing, by the mobile machine, the medical treatment on a patient; determining, by the mobile machine, that the medical treatment is completed and the mobile machine is disconnected from the patient; automatically navigating the mobile machine to a stationary docking station of the medical system; and determining that the mobile machine is connected to the docking station through one or more connectors, and in response, receiving, by the mobile machine, at least one of an electrical charge, a refill of one or more supplies, a cleaning, or a drain of waste.

Transfer sets with filters, including transfer sets with filters for peritoneal dialysis (PD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, a transfer set includes a first connector configured to be coupled to a disposable set of a PD system, a second connector configured to be coupled to a catheter of the PD system, and a fluid channel extending between the first connector and the second connector. The transfer set further includes a filter positioned within the fluid channel and configured to filter contaminants from solution flowing within the fluid channel between the first connector and the second connector. In some embodiments, the transfer set further includes a one-way valve positioned between the filter and the second connector and configured to prevent fluid from flowing through the one-way valve in a direction toward the filter.

Dialysis systems and methods for operating dialysis machines (e.g., peritoneal dialysis machines) for conducting dialysis treatments are disclosed. The dialysis system may include a dialysis machine for transferring dialysate to a patient from a dialysate source. The dialysate may flow from the dialysate source through a cassette (e.g., a disposable cassette) positionable within a port formed in the dialysis machine. The dialysis system may also include a cleaning cartridge insertable into the port. The cleaning cartridge may be arranged and configured to collect, remove, etc. any foreign material or debris from the port.