The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.

An extracorporeal blood treatment device is disclosed. The device includes a blood treatment unit connected to an extracorporeal blood circuit, a waste liquid discharge line for evacuating waste treatment liquid from the blood treatment unit, and a collecting container for collecting waste treatment liquid evacuated via the waste liquid discharge line. The collecting container is removably connected to the waste liquid discharge line via a one way valve. A collecting container for a device is also disclosed. The container includes a waste fluid input line, wherein a one way valve is arranged in the waste fluid input line.

A filter CF1 for filtering dialysis fluid comprises the following: a housing 52 inside of which a filter material 51 is accommodated and which is vertically long; an introduction port 53 that is disposed in the lower part of the housing and that introduces dialysis fluid from an upstream-side flow path 23a; a filtered fluid lead-out port 54 through which filtered dialysis fluid, which has passed through the filter material, is lead out from the upper part of the housing to a downstream-side flow path 23b; and an unfiltered fluid lead-out port 55 through which unfiltered fluid is lead out from the upper part of the housing to a waste fluid flow path 57. When removing the filter from a dialysis fluid circuit 4, fluid is suctioned from the inside of the housing via the upstream-side flow path by using fluid suction means 64A, and a gas is caused to flow into the housing from at least either one of the waste fluid flow path and the downstream-side flow path by using gas inflow means 65. The fluid may be suctioned from the downstream-side flow path and the gas may be caused to flow in from the upstream-side flow path, or the fluid may be suctioned from the waste fluid flow path and the gas may be caused to flow in from the downstream-side flow path. Residual fluid in the filter can be reduced.

A line holder assembly may include a molded nest coupled to an anchor pad or base having a flat bottom with sufficient surface area in contact with a table or other surface to secure the line holder assembly in place during use. The nest is designed to extend around a cart or table edge and having tabs to accept a line holder for holding and organizing lines and which may be disposed in a vertical position. The anchor base may be made of or otherwise include a flexible, rubber-like material, such as silicone, and thereby use the material's natural stickiness to provide fixation to the table or cart. The line holder assembly may be beneficially used in connection with a home dialysis machine, such as a peritoneal dialysis (PD) cycler, in which lines and connectors are desirably organized and anchored during a dialysis treatment.

The present disclosure relates to diffusion and/or filtration devices comprising hollow fiber membranes, e.g., ultrafilters for water purification, plasma filters, or capillary dialyzers for blood purification; housings and end caps for the devices; and methods for the production of the devices.

A machine for extracorporeal blood treatment including a housing for accommodating operational components of the machine for extracorporeal blood treatment and a light-emitting unit having no diffusion disk for displaying an operating and/or therapy condition of the machine according to the principle of ambient light. The light-emitting unit is arranged in a predetermined sequence and/or with predetermined shaping on at least one portion of the housing. The light-emitting unit is a flexible light conductor having at least one end-face light coupling surface at a first end and at least one end-face light output surface at a second end or alternatively a self-luminous flat and/or flexible OLED unit.

An array of hollow nanotubes is configured and dimensioned to allow impurities to transport through the hollow nanotubes from a first space containing an impurity-laden fluid to a second space where the impurities may be collected for removal, allowing fluids, such as blood, to be purified.

Described here are systems, devices, and methods of renal replacement therapy. In some variations, a continuous ambulatory dialysis device may comprise a first fluid conduit configured to receive a fluid from a patient, a second fluid conduit configured to output the fluid to the patient, and an electroosmotic pump configured to pump and filter the fluid. The electroosmotic pump may be coupled between the first fluid conduit and the second fluid conduit. The electroosmotic pump may comprise a first electrode configured to adsorb urea in the fluid, a second electrode, and a porous substrate coupled therebetween.

The present invention relates to novel co-polymers and their use in the manufacture of porous membranes for haemodialysis application. In particular, such a co-polymer comprises a first segment comprising recurring units poly(aryl ether sulfone) [PAES recurring units], and a second segment comprising-recurring units poly(vinyl pyrrolidone) [PVP recurring units], wherein said first segment and said second segment are linked together via a group of formula —O-Ph-NH—C(═O)—C(CH.sub.3).sub.2—CH.sub.2—.

A negative-balanced isolated pelvic perfusion method, in which a drug is administered into the closed pelvis while keeping the volume of suction from the vein larger than that of injection into the artery, does not require allogeneic blood transfusion. A perfusion device is for recovering a liquid containing a drug and/or blood from a tube connecting to the inferior vena cava and for injecting the liquid obtained into a tube connecting to the artery, provided with a unit for closing the inside of the pelvis by including a unit for blocking the artery from the heart to the pelvis, a unit for blocking the inferior vena cava from the pelvis to the heart, and a unit for blocking a blood flow from the pelvis to the lower limbs. The perfusion device is provided with a pelvic perfusion unit equipped with a reservoir, an autotransfusion unit, and a dialysis unit.