A renal failure therapy system having an electrically floating fluid pathway is disclosed. The example system includes a dialyzer, a blood circuit in fluid communication with the dialyzer, and a dialysis fluid circuit in fluid communication with the dialyzer. The system also includes an electrically floating fluid pathway comprising at least a portion of the blood circuit and at least a portion of the dialysis fluid circuit. The only electrical path to ground is via used dialysis fluid traveling through the renal failure therapy system to earth ground. The disclosed system enables at least one electrical component in the at least a portion of the dialysis fluid circuit of the electrically floating fluid pathway to be electrically bypassed.

Provided is a blood processing apparatus having multiple fluid chambers each having an internal space, a chamber pressurizing member compressing or expanding the internal spaces of the chambers, a chamber pressurizing member driver driving the chamber pressurizing member, and a flow control unit. The chambers are each connected with a first flow tube through which a fluid is provided to the chamber and a second flow tube through which a fluid of the chamber is discharged therefrom. The flow control unit controls a flow through the flow tubes connected to the multiple fluid chambers.

A blood oxygenator includes a housing having a first end opposite a second end with a sidewall extending between the first end and the second end along a longitudinal axis. The housing defines an interior chamber having a liquid inlet at the first end and a liquid outlet at the second end. The oxygenator further includes a gas exchange assembly positioned within the interior chamber. The gas exchange assembly includes a retainer having an upper cap spaced apart from a lower cap by one or more spacers, and a gas exchange medium disposed between the upper cap and the lower cap. The gas exchange medium has a plurality of subunits stacked on top of each other, with each subunit having a plurality of layers of hollow fiber mats.

A blood oxygenator includes a housing having a blood inlet, a blood outlet, a gas inlet, and a gas outlet; and a gas exchange medium having a plurality of hollow fibers in fluid communication with the gas inlet and the gas outlet. Each of the hollow fibers has a roughened outer surface configured to decrease a thickness of a boundary layer at an interface between blood and the roughened outer surface and increase a gas exchange rate at the interface.

A filtration cell (10) for a biological sample including an upper chamber for receiving the biological sample to be filtered, a lower chamber in fluid communication with the upper chamber, and a filtration membrane (14) positioned between the upper chamber and the lower chamber is disclosed. A surface of the filtration membrane has a contact angle >90°. The flow of the biological sample through the upper chamber may be tangential to the filtration membrane and a filtrate passing through the filtration membrane may be collected in the lower chamber. Also, a method of filtering a biological sample including passing the biological sample through an upper chamber of a filtration cell as described above and collecting a filtrate in the lower chamber is disclosed.

A system for holographic control of a hemodialysis machine according to one embodiment includes a hemodialysis control system of the hemodialysis machine and a holographic system communicatively coupled to the hemodialysis control system.

The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.

A dialysis system including a disposable fluid pumping cassette including at least one flexible membrane attached to a housing and at least one port extending from the housing, the at least one port including a spike; at least one dialysis fluid supply in fluid communication with at least one tubing and tubing connector; an autoconnection device including a shuttle for moving the at least one tubing and tubing connector towards the spike of the at least one port, the autoconnection device including at least one lead screw in mechanical communication with the shuttle, a motor and power transmission equipment to transmit power from the motor to the at least one lead screw; and a controller programmed to operate the motor to move the at least one tubing and tubing connector towards the spike of the at least one port of the disposable fluid pumping cassette.

A connector for use with a dialyzer to connect a conduit from a dialyzer with a conduit from a dialysate source. The connector includes a sleeve (female component) and a collet (male component). The sleeve has a generally cylindrical shape with an opening at one end having a circular shape with at least one slot positioned along the periphery of the circular shape. The sleeve also includes at least one flexible finger having a barb at a free end. The collet is configured to be housed within an interior chamber of the sleeve and has first and second gaps to house the barbs and first and second deflectable flanges to lock into recesses in a conduit.

The present disclosure relates to bundles of hollow fiber membranes and a process for their production. The bundles are used for the manufacture of filtration and/or diffusion devices, e.g., capillary dialyzers.