The present invention relates to an apparatus or making extracorporeal blood circulation available, in particular a heart-lung machine, comprising a venous connection and an arterial connection, between which a blood reservoir, a blood pump and a bubble detector for the detection of air bubbles are provided, with, downstream of the bubble detector, an arterial line leading to the arterial connection via an arterial clamp and a bypass leading via a bypass clamp back into the blood reservoir which is connected to a pump extracting air from the blood reservoir. In addition, the present invention relates to a method of operating such an apparatus.

An oxygen supply unit for use with a blood oxygenator comprises an oxygen concentrator and a carbon dioxide scrubber. In an on-line operational mode, oxygen-rich gas from the oxygen concentrator is predominantly supplied to the blood oxygenator with a reduced flow of recycled gas from the concentrator. In an off-line operational mode where the oxygen supply unit is being powered by battery only, a larger flow of recycled gas from the blood oxygenator is passed through the carbon dioxide scrubber and combined with a lesser amount of oxygen-rich gas from the oxygen concentrator. The oxygen supply unit may be used in combination with a blood pump and oxygenator to provide ambulatory blood oxygenation to patients with compromised lung function.

In one exemplary embodiment, a wearable extracorporeal life support device includes a catheter fluidly connected to a pump and first and second modular extracorporeal life support components. The device may also be configured to be attached to a garment. The pump and the first and second modular extracorporeal life support components may be fluidly connected in series. The pump and the first and second modular extracorporeal life support components may also be fluidly connected in parallel. The first modular extracorporeal life support component may be a lung membrane and the second modular extracorporeal life support component may be a dialysis membrane.

An extracorporeal blood treatment system including a blood oxygenator having an inlet for receiving deoxygenated blood and an outlet for expelling oxygenated blood. The system also includes a recirculation flow path for recirculating a portion of the oxygenated blood exiting the oxygenator outlet back into the oxygenator inlet. The system may also include a dual-lumen cannula coupled to the oxygenator. The cannula includes a manifold with a first blood pathway communicating with the oxygenator outlet, a second blood pathway communicating with the oxygenator inlet, and a third blood pathway connecting the first blood pathway to the second blood pathway. The manifold passes oxygenated blood received from the oxygenator through the first blood pathway, passes deoxygenated blood received from the patient through the second blood pathway, and passes a portion of the oxygenated blood from the first blood pathway through the third blood pathway to be combined with deoxygenated blood in the second blood pathway.

Disclosed are an oxygenator and an extracorporeal membrane oxygenation device. The oxygenator includes: a housing, an upper end cover of the housing being provided with a blood inlet, and a lower end cover of the housing being provided with a blood outlet; and an oxygenation chamber, arranged in the housing, where the axis of the blood inlet and the axis of the blood outlet coincide with the axis of the oxygenation chamber. The blood inlet and the blood outlet are arranged at the center of the upper and lower parts of the oxygenation chamber, after the blood entering the oxygenation chamber is uniformly diffused to the periphery, the blood uniformly flows to the blood outlet from top to bottom due to gravity. The extracorporeal membrane oxygenation device includes the described oxygenator.

The present invention relates to a membrane gas exchanger having a housing in which a first chamber and a second chamber as well as a membrane are arranged, wherein the membrane is gas permeable and liquid impermeable and separates the first chamber and the second chamber from one another, wherein the first chamber forms the blood side and the second chamber forms the gas side of the membrane gas exchanger, and wherein the first chamber has a blood inlet and a blood outlet, and wherein the second chamber has a gas inlet and a gas outlet, and wherein the blood inlet, the blood outlet, the gas inlet, and the gas outlet are arranged at the housing, wherein the housing is the housing of a dialyzer, and wherein a first adapter is provided that has an inlet and at least two outlets, with the inlet being connected to the gas outlet of the housing.

A system (20) including a heater/cooler module (22) to heat/cool a first fluid in a primary circuit (28), a heat transfer fluid circuit (24) to provide a second fluid to a target device (38) to heat/cool the target device (38), and a heat exchanger (26) including at least part of the primary circuit (28) and at least part of a secondary circuit (36) through which the second fluid flows to facilitate heat transfer between the first fluid and the second fluid. The primary circuit (28) and the secondary circuit (36) are separate circuits and the first fluid and the second fluid remain separated in the system. Also, the system is modular, such that the elements can be stacked to increase heating/cooling capability and/or to increase the number of heating/cooling channels, and the system is compatible with portable applications, such as ambulance, aircraft, and helicopter applications, and with battery operation and/or the use of uninterruptible power supplies.

An oxygenation system for a ventilation system comprises an inlet for receiving oxygenation gas at an oxygenation gas flow rate into an oxygenator, and an exhaust gas remover to remove exhaust gas at an exhaust gas flow rate from the oxygenator, and one or more flow controllers for controlling the exhaust gas flow rate relative to the oxygenation gas flow rate. This allows the amount of total gas entering the oxygenator and the amount of total gas removed from the oxygenator to be controlled with greater accuracy.

A system configured to enclose a premature fetus within an extracorporeal environment to promote growth of the fetus and increase viability of the fetus. The system includes a chamber having an interior space configured to enclose the fetus, a first fluid circuit that delivers sterile fluid to the chamber, and a second fluid system that transfers oxygen to the fetus. The system chamber includes a stop mechanism including a clamp and an actuator, the clamp positioned in the interior space, the actuator coupled to the clamp such that movement of the actuator moves the clamp, and the actuator positioned at least partially outside the interior space.

Embodiments of the present disclosure provide a membrane oxygenator including an upper cover, a lower cover, a shell, and an oxygenation structure. Both ends of the shell are connected with the upper cover and the lower cover respectively. The oxygenation structure includes a mandrel, an oxygen pressure membrane, and a temperature-changing membrane, wherein an upper end of the mandrel enters a first blood path space of the upper cover, a lower end of the mandrel is opposite to a blood outlet of the lower cover, the oxygen pressure membrane is provided around the mandrel and connects a first gas path space and a second gas path space, and the temperature-changing membrane wraps around the oxygen pressure membrane. A gap is provided between the temperature-changing membrane and an inner wall of the shell. A blood inlet is provided on the shell near the upper cover.