Methods and systems are provided for anesthesia systems for heart-lung machines. In one embodiment, a system comprises: a cardiopulmonary bypass machine; and an anesthesia machine operably coupled to the cardiopulmonary bypass machine, the anesthesia machine adapted to control a flow of vapor through the cardiopulmonary bypass machine.

The present disclosure provides a system for oxygenating blood. The system may include an implantable blood pump that may draw a supply of blood from the circulatory system of a mammalian subject, such as a human being. The blood pump may provide the supply of blood to an adaptor, where the supply of blood may be supplied to either or both of a first branch or second branch. The first branch may lead to an external blood oxygenator. The oxygenator may oxygenate the blood, and the blood may be returned to the circulatory system of the mammalian subject. The second branch may bypass the oxygenator and may connect to the circulatory system of the mammalian subject. In this regard, while the blood is supplied to the second branch, the oxygenator may be disconnected and blood may be prevented from entering the first branch.

Treatment of cardiac tissue via an implantable heart treatment device is described. A device embodiment includes, but is not limited to, a substrate configured for implantation within a body; an electromagnetic signal generator coupled to the substrate and configured to generate one or more electric signals configured to stimulate one or more tissues of a heart within the body; and an energy-carrier molecule delivery device coupled to the substrate and configured to supply one or more non-oxygen cellular energy sources to one or more tissues of the heart within the body.

A blood processing apparatus may include a heat exchanger and a gas exchanger. At least one of the heat exchanger and the gas exchanger may be configured to impart a radial component to blow flow through the heat exchanger and/or gas exchanger. The heat exchanger may be configured to cause blood flow to follow a spiral flow path.

Treatment of cardiac tissue via an implantable heart treatment device is described. A device embodiment includes, but is not limited to, a substrate configured for implantation within a body; an electromagnetic signal generator coupled to the substrate and configured to generate one or more electric signals configured to stimulate one or more tissues of a heart; and an oxygenator coupled to the substrate and configured to supply one or more oxygenated molecules to one or more tissues of the heart, the oxygenator including a blood inlet portion, a blood outlet portion, and an oxygen exchange portion positioned between the blood inlet portion and the blood outlet portion, the oxygen exchange portion including a high surface area oxygen exchanger configured to transfer one or more oxygenated molecules from the high surface area oxygen exchanger to blood passing from the blood inlet portion to the blood outlet portion.

A gas exchange system may include an elongate member including a liquid circuit and configured to be inserted into a body lumen, and a gas exchanger in fluid communication with the elongate member. A gas transfer fluid may be disposed within the liquid circuit of the elongate member. The gas transfer fluid may be configured to absorb carbon dioxide from a body fluid disposed in the body lumen, and subsequently release the carbon dioxide in the gas exchanger.

An oxygenator unit adapted for the use in an extracorporeal blood treatment device. The oxygenator unit includes an oxygenator having a gas inlet and a supply line for conducting a gas provided at the gas inlet, the supply line being connectable to a source of a pressurized gas containing oxygen, wherein the oxygenator unit further includes a pressure relief valve provided in the supply line upstream of the oxygenator, the pressure relief valve being adapted to release pressure exceeding a predetermined pressure value from the supply line, thereby preventing a critical overpressure in the oxygenator.

A blood gas management device comprises a blood passage having a gas-blood interface with a plurality of gas passages, and is arranged to direct a flow of supply gas from the gas inlets through the gas passages to the gas outlets, and to allow a flow of blood in a blood flow path through the blood passage to thereby permit an exchange of blood gas with the supply gas via the interface. The blood gas management device comprises a supply gas distribution arrangement allowing the supply gas to be provided from different directions relative to the blood flow path. This provides an improved gas-transfer gradient at different locations along the gas passage.

A blood processing apparatus including a blood supply unit, a centrifuge, a light irradiation unit, a filtering device, and a blood collection unit, which is characterized in that blood is introduced into the centrifuge and centrifuged, the centrifuged blood is passed through a transparent tube provided in the light irradiation unit while being irradiated with light applied, from the outside of the transparent tube, by a light irradiation device configured to include an infrared lamp with a wavelength of 830?5 nm, a red light-emitting diode (LED) lamp with a wavelength of 635?6 nm, a blue LED lamp with a wavelength of 420?5 nm, a green LED lamp with a wavelength of 530?5 nm, a yellow LED lamp with a wavelength of 585?5 nm, and ultraviolet (UV) lamps, and the blood irradiated with the light is filtered using the filtering device and collected in the blood collection unit.

Disclosed is a method for treating a renal condition by loco-regional perfusion of one or both of a patient's kidneys (1810). A closed circuit may be formed with a perfusion catheter (1822) positioned in the renal artery of the kidney, a recovery catheter (1824) positioned in the renal vein of the kidney, and an external membrane oxygenator (1820) disposed therebetween. A perfusate containing, for example, a drug may be circulated through the closed circuit while isolating the closed circuit from the patient's systemic circulation.