A method is provided for detecting leaks in a disposable medical fluid cassette that includes a base and a flexible membrane attached to the base in such a way that the base and the flexible membrane cooperate to at least partially form a fluid passageway. The method includes applying a first force to the flexible membrane, measuring a first physical property of a system that includes the medical fluid cassette a medical fluid pumping machine, removing the first force from the flexible membrane, applying a second force to the flexible membrane, measuring a second physical property of the system, and determining whether the medical fluid cassette leaks based on a comparison of the first physical property and the second physical property.

A dialysis system may include a dialysis machine (e.g., a peritoneal dialysis machine) having a fluid system for delivering fluid (e.g., dialysate) to a patient. The dialysis machine may include at least one processor and a memory coupled to the at least one processor, the memory comprising instructions that, when executed by the processor, may cause the at least one processor to determine volume information for a fluid system of a dialysis machine, wherein the volume information may comprise a patient line volume and an accuracy adjustment volume, and to determine a priming volume to prime the fluid system with a fluid based on the volume information. Other embodiments are described.

A method of controlling a medical fluid therapy machine display brightness includes: performing a medical fluid therapy using the medical fluid therapy machine, the medical fluid therapy machine including a display; sensing an amount of ambient light impinging the display without receiving light directly from the display; controlling a level of backlight brightness for the display based on the amount of ambient light sensed; and displaying information relating to the medical fluid therapy on the display using the controlled level of backlight brightness.

An air purging method includes: (a) detecting a low fluid level in a blood circuit indicating a high amount of air in the blood circuit; (b) stopping a blood pump; (c) closing a venous patient line; (d) opening a blood circuit air vent valve and a drain valve; and (e) running the blood pump to meter air through the air vent valve and the drain valve to a drain.

A method for the re-anticoagulation of platelet rich plasma in a blood apheresis system includes priming the blood apheresis system with anticoagulant, such that a volume of anticoagulant is transferred to a PRP container. The method may then transfer the anticoagulant within the PRP container to a red blood cell container, and collect a volume of platelet rich plasma within the PRP container. The platelet rich plasma may be collected in a plurality of cycles. Between collection cycles, the method may transfer a portion of the volume of anticoagulant from the red blood cell container to the PRP container.

An apparatus for ultrafiltration of a patient being overhydrated due to congestive heart failure, comprising a tube set including a connector for connection to a patient line for access to the peritoneal cavity of the patient. A flow pump is arranged for addition and removal outflow and inflow (recirculation) of fluid from/to the peritoneal cavity. An osmotic agent peristaltic pump is arranged for replenishment of glucose solution to the fluid added to the peritoneal cavity for promoting ultrafiltration. The glucose is replenished intermittently for keeping a concentration of glucose substantially constant in the peritoneal cavity. The flow pump comprises a pressure chamber with rigid walls and a flexible pump bag arranged therein. An air pump pressurizes the chamber for outflow of fluid from the peritoneal cavity by a sub pressure and inflow of fluid to the peritoneal cavity by an overpressure, which pressures are maintained within safe limits.

A peritoneal dialysis system is provided that includes a hardware unit, a disposable unit received by the hardware unit, and a controller. The hardware unit includes a recessed area, a piston having a contact surface, a pneumatic source for supplying a negative pressure, and an actuator configured to move the contact surface of the piston into and out of at least a portion of the recessed area. The disposable unit includes an outer member fitted at least partially within the recessed area of the hardware unit and a moveable membrane positioned between the contact surface of the piston and the outer member when the disposable unit is received by the hardware unit. The controller is configured to cause the pneumatic source to apply the negative pressure to the moveable membrane so as to conform the moveable membrane to a shape of the contact surface of the piston and follow the contact surface when the piston is moved towards and away from the outer member fitted at least partially within the recessed area.

An IV pole mountable, therapeutic infusate processing device is incorporated into a hypothermia system to receive therapeutic fluid(s), such as normal saline, peritioneal dialysis solution, or other crystalloid solution, to heat such therapeutic fluid(s) a few degrees centigrade above normal body temperature and to direct the resulting heated infusate to and through a selected anatomical portion of a patients body to raise the temperature of that body portion so as to affect any cancerous or other tumors that may be located therein. The processing device is provided with touch screen controls and visual indicators to facilitate its proper use; while the system further includes temperature and pressure sensors to monitor the hyperthermia processing to insure patient safety.

A peritoneal dialysis system includes (i) a fill container, and (ii) an energizing unit that removably accepts the fill container, the energizing unit including a sterilization source so configured and arranged relative to the fill container when accepted by the energizing unit to place fluid within the fill container in a physiologically safe condition for delivery to the peritoneal cavity of a patient.

A system for preparing a medicament for use by a medicament user includes a proportioning machine with a controller and pumping and clamping actuators to engage a fluid circuit having pumping and clamping portions that engage with respective actuators of the proportioning machine. The fluid circuit includes a mixing container that is initially empty and later filled with two different concentrated medicaments from different concentrate containers and with purified water. The proportioning machine is configured to receive purified water and to mix it with the concentrated medicaments to produce a medicament and to output the medicament to a medicament consumer in such a way that to the medicament consumer the medicament appears to be provided from a bag of medicament. Custom mini batches of medicament may be produced by varying the amount of the concentrates and water.