Provided is a biological fluid-treating filter for treating a biological fluid containing erythrocytes, which has a matrix and a polymer retained by the matrix, the polymer having a zwitterion-containing functional group and a basic nitrogen-containing functional group. By using the filter in which the polymer has the zwitterion-containing functional group and the basic nitrogen-containing functional group, it is possible to treat the biological fluid containing erythrocytes without adversely affecting the erythrocytes.

A blood based solute monitoring system for measuring at least one blood solute species that has a first recirculation flow path in fluid communication with a dialyzer. The first recirculation flow path is configured to allow a fluid to recirculate through a dialyzer such that the concentration of at least one solute species in the fluid becomes equilibrated to the solute species concentration of the blood in a blood compartment of the dialyzer. The blood solute monitoring system has at least one sensor to measure a fluid characteristic.

A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.

A sorbent based monitoring system for measuring the solute concentration of at least one component of a fluid. The system has a sorbent regeneration system for regeneration of the fluid and has a sorbent cartridge that has at least one material layer. The fluid is conveyed through the sorbent cartridge and contacts at least one sensor after having contacted at least one material layer.

Provided is A PRP extraction kit comprises: a body that has an upper accommodation space, a lower accommodation space that is located below the upper accommodation space, and a communication passage which communicates the upper accommodation space and the lower accommodation space and of which a fluid passage area becomes narrower as it goes upward or downward, in the interior thereof; a valve unit that is located in the communication passage and allows flow of the communication passage to go only in one direction while being moved by a self-weight based on a change in a vertical position of the body; and a variation means that is coupled to a lower side of the body and vertically moves based on manipulation of a user to vary the volume of the lower accommodation space.

Treatment methods are described using blood collected from a donor after subjecting thereof to remote conditioning such as remote ischemic conditioning via several episodes of short-term limb occlusion. Blood containing remote conditioning substances or a biologically active preparation containing such substances may be stored and used at a future time to afford a health benefit to the treatment subject. Extraction of remote conditioning substances may be done extracorporeally using dialysis or other blood processing methods following by returning of blood to the donor. Extraction of remote conditioning substances may be done during the time periods of their maximum presence in donor blood.

Circulating cell clusters found in subjects with cancer, autoimmune conditions, infections, or other diseases, can be trapped or disrupted by filtering them with an intra- or extracorporeal device and, in some cases, exposing them to a substance, such as enzyme, that reduces intercellular adhesion.

A device for measuring at least one measurand is disclosed which comprises a sensor device with at least one sensor and, via at least one medium-carrying detection path, can be connected to at least one of a plurality of devices outputting at least one flow of a medium to be captured. The at least one sensor is arranged to selectively detect at least one measurand with respect to at least one medium flow output by one of said plurality of devices. A system which includes the sensor device in a centralized way further comprises at least one device outputting the flow of the medium to be measured at at least one outlet, wherein one of the devices can be selectively selected and can be connected to the sensor device for a predetermined period of time if several devices outputting a medium flow are connected to the sensor device for measuring at least one measurand.

The present invention provides a filter for separating particles and/or catalyzer for particle reaction in a fluid. The device comprising array of passageways fabricated on a die wherein the passageway size is controlled by actuators. The passageway size is monitored and the actuators controlling the passageway size are activated conditionally upon the passageway size monitoring. Using movable actuators the passageway can achieve passageway size that is less then the fabrication minimal resolution. Proper locating, setting and/or activation of the actuators create passageways that can perform filtration of particles, trapping of particles and catalyzing particles reaction.

An enclosure for containing a portable hemodialysis unit includes a housing suitable to support components for performing hemodialysis including a dialyzer, one or more pumps to circulate blood through the dialyzer, a source of dialysate, and one or more pumps to circulate the dialysate through the dialyzer. The housing may have a front panel at which blood circuit connections and dialysate fluidic connections are located, e.g., blood line connections for patient blood access, connections for a reagent supply, dialyzer connections for both blood flow and dialysate, etc. The enclosure may also include a pair of vertical, side-by-side doors hingedly mounted to the housing. With the doors in the closed position, access to the patient access and dialysate fluidic connections may be blocked, and the doors may allow for the retention of heat in the housing suitable for disinfection during a disinfection cycle.