Fluid reactors include a sealed housing enclosing a reactor core that includes at least one substrate-free multichannel reactor core element. Each reactor core element is made from a non-substrate mounted, open pore cellular network material having an asymmetric, tortuous, bi-continuous two-phase material structure and contains multiple perforating fluid channels. Multiple reactor core elements can be serially and/or parallelly piped in a sealed manner to form a reactor core for a fluid reactor with a higher production capacity.

An extracorporeal blood pump assembly includes a blood pump and an extracorporeal membrane oxygenator (ECMO). The blood pump includes a pump housing, a rotor, and a flow converter positioned downstream from the rotor to convert non-axial flow from the rotor to axial flow. The pump housing defines an inlet and an outlet. The ECMO includes a membrane housing and an oxygenator membrane disposed within the membrane housing. The membrane housing is removably connected to the pump housing at one of the pump housing inlet and the pump housing outlet.

An extracorporeal blood treatment apparatus, comprises: at least a pressure sensor (24,25) located in a respective measurement site on an extracorporeal blood circuit (6, 7); an electronic control unit (23) operatively connected at least to the pressure sensor (24, 25). The electronic control unit (23) is configured to perform at least the following procedure: receiving from the pressure sensor (24, 25) a signal correlated to a measured blood pressure (P1measured, P2measured) in the measurement site; correcting the blood measured pressure (P1measured, P2measured) through a mathematical correction model to obtain a blood actual pressure (Pinlet, Poutlet) in a reference site other than the measurement site. Between the reference site and the measurement site, a circuit section and, optionally, at least one additional device (18, 27, 28) is/are positioned. The mathematical correction model is a model of a pressure drop in the circuit section and, optionally, in the additional device (18, 27, 28).

The invention concerns a control or regulating device with a control or regulating unit, which both controls or regulates a volumetric blood flow flowing through a blood pump as well as a volumetric flow of a gas able to flow through a gas exchange unit.

An article configured to warm and monitor a patient during a dialysis treatment, the article includes one or more heating elements. The article also includes one or more sensors configured to monitor a condition of the patient during the dialysis treatment. The article also includes a fabric portion configured to receive the one or more heating elements and the one or more sensors and position the one or more heating elements and the one or more sensors on the patient during treatment. The article also includes a transmitter configured to transmit information from the one or more sensors to a dialysis machine and an electrical connector configured to provide power to at least one of the one or more heating elements and the one or more sensors.

Disclosed are devices and methods directed to oxygenators for use in extracorporeal circuits for supporting a fetus. An oxygenator for use with an extracorporeal circuit includes a housing defining a cavity therein and a gas exchanger disposed within the interior cavity. The cavity is configured to receive blood a fetus. The gas exchanger is configured to receive a sweep gas and further configured to contact the blood within the cavity, such that at least oxygen gas and carbon dioxide gas is permitted to diffuse between the blood and the gas exchanger.

A heat exchanger for an oxygenator device has multiple hollow fiber membranes that each have a hollow portion through which a heat medium passes, wherein the fibers are wound as a cylinder body. Each of the hollow fiber membranes follows a path between opposing ends of the cylinder body which is tilted with respect to a central axis of the cylinder body and is wound around the central axis of the cylinder body, wherein a tilt angle θ with respect to the central axis ranges from 22° to smaller than 67°, and wherein a constituent material of each of the hollow fiber membranes has a Young's modulus E ranging from 2.6 GPa to 0.07 GPa. During winding, the hollow fiber membranes are stretched according to a stretching rate between 0.5% and 3.0% and then fixed at the ends to maintain the stretching.

A system for removing gaseous micro emboli from blood prior to oxygenation. The system including a module having a blood inlet, a blood outlet, and a port configured to provide atmospheric or sub-atmospheric pressures, and microporous hollow fibers situated in the module and fluidly coupled to the port to provide the atmospheric or sub-atmospheric pressures inside the microporous hollow fibers. The module is configured to receive the blood through the blood inlet such that the blood flows from the blood inlet to the blood outlet around outside surfaces of the microporous hollow fibers such that at least some of the gaseous micro emboli in the blood are drawn from the blood through the microporous hollow fibers by the atmospheric or sub-atmospheric pressures.

A heating system for medical fluid that comprises a receptacle for medical fluid to be heated, a heating element powered by a power supply inducing a leakage current (to ground) ranging between 100 and 10 μA. The heating system further comprises an interface device (for example, an electrical insulation and thermal interface device) disposed between the heating element and the medical fluid contained in the receptacle, allowing the heating system to induce a leakage current in the medical fluid that is less than 10 μA at the applied part.

A gas delivery system is provided. The gas delivery system includes a pump operable to receive blood from a patient. A gas transfer unit is in fluid communication with the pump and operable to receive the blood from the pump and deliver a therapeutic amount of xenon gas to the blood. A patient connector withdraws and/or infuses the blood into the patient.