A connector arrangement (10) for connecting to a fluid chamber (6) of a blood treatment unit (4) for extracorporeal blood treatments. The connector arrangement (10) includes a connector device (11) with a connector body (47) comprising a port opening (43) and an interior wall (50) defining a port space (39) designed to receive a first fluid port (8A) of the fluid chamber (6). The connector device (11) also incorporates a fluid path (35a) extending from the port space (39) to a first end opening (51) of the connector device (11), and an air path (36a) extending from the port space (39) to a second end opening (52) of the connector device (11), wherein the fluid path (35a) and the air path (36a) are separate paths. Also a system (1) for extracorporeal blood treatment including the connector arrangement (10) and a method for priming the fluid chamber (6).

An extracorporeal circulation apparatus including a blood circuit including an arterial blood circuit and a venous blood circuit whose proximal ends are connected to a blood purifier, the blood circuit allowing a patient's blood to extracorporeally circulate from a distal end of the arterial blood circuit to a distal end of the venous blood circuit; a discharge unit through which a priming solution supplied into the blood circuit is discharged to an outside; a negative-pressure-generating unit that generates a negative pressure in a region of the blood circuit, the region being filled with the priming solution; and a control unit that controls the negative-pressure-generating unit. The control unit executes a priming step in which the priming solution supplied into the blood circuit is discharged through the discharge unit while a flow route in the blood circuit is filled with the priming solution; a negative-pressure-generating step in which, after the priming step, a negative pressure is generated in the region by the negative-pressure-generating unit; and a discharge step in which bubbles in the region subjected to the negative pressure generated in the negative-pressure-generating step are caused to flow and are discharged through the discharge unit.

A device for establishing venous inflow to a blood reservoir of an extracorporeal blood circulation system includes a restricting unit for restricting a venous inflow line and a vacuum unit for supplying vacuum to the blood reservoir. The device includes a control unit that, upon setting the desired venous flow rate, automatically supplies a first actuating signal to the restricting unit for restricting venous inflow to the blood reservoir and supplies a second actuating signal to the vacuum unit for establishing a degree of vacuum within the blood reservoir, so as to achieve the set venous flow rate. The device includes a venous flow sensor.

A blood purification device includes a blood circuit for extracorporeally circulating blood of a patient; a liquid supply circuit for supplying a supply liquid to the blood circuit or to a blood purifier provided on the blood circuit and a waste liquid circuit for discharging the waste liquid from the blood purifier. Each of the blood circuit, the liquid supply circuit and the waste liquid circuit comprises a flexible tube. The blood purification device comprises a tube identification unit that performs a tube identification process for identifying a tube used for the blood circuit, the liquid supply circuit or the waste liquid circuit or determining whether or not there is an abnormality in the tube, based on an amount of liquid sent from a peristaltic pump provided on the blood circuit, the liquid supply circuit or the waste liquid circuit, or pressure fluctuation in the circuit, caused when driving the pump for a predetermined time.

The invention relates to a pneumatic manifold for controlling a fluid level in an arterial and/or venous drip chamber of a dialysis system. The pneumatic manifold includes pneumatic valves fluidly connected to conduits and one or more pumps. Selectively activating the pneumatic valves can result in pressure changes for raising or lowering a fluid level in the arterial and/or venous drip chambers.

A blood purification device 1 is provided with: a blood circuit 2 for extracorporeally circulating blood of a patient; a blood purifier 3 provided in the blood circuit 2; a gas-liquid separator 24 which is provided in the blood circuit 2 and located on the downward side of the blood purifier 3 in the direction of blood flow, and separates air bubbles contained in blood flowing thereinto; and a liquid surface adjustment unit 6 capable of adjusting the liquid level in the gas-liquid separator 24. The liquid surface adjustment unit 6 performs control such that the liquid level during priming is higher than the liquid level during treatment.

The present invention provides a method, system, and apparatus that can substantially reduce the recirculation of venovenous extracorporeal membrane oxygenation (VV ECMO) associated with the two-site, single-lumen cannulation approach. Actively-controlled flow regulators comprising balloon, occluder and reservoir can be individually or collectively equipped on the drainage and/or infusion cannulas to accomplish the goal of maximizing VV ECMO support efficacy. Three specific embodiments are introduced to illustrate the practical enforcement of the proposed blood flow control in reference to the heart rhythm, aiming at achieving the maximal reduction of oxygenated blood flow recirculating back to the VV ECMO circuit.

Disclosed is an artificial heart and lung apparatus (100) that can be connected to a patient (P), and transfers removed blood to a human body via a roller pump (120), the system including: the roller pump (120); a blood removal line (101) which transfers removed blood to the roller pump (120); a first blood transfer line (104) that transfers blood, which is transferred from the roller pump (120), to the human body; a blood removal rate sensor (111) that is provided in the blood removal line (101); and a control unit (140), in which the control unit (140) performs control such that a blood transfer rate of the roller pump (120) is in a specific range with respect to a blood removal rate measured by a blood removal rate sensor (111).

An extracorporeal circulation blood or treatment device (100) comprising an arterial pressure sensor (112) and a blood pump (111) is set up to determine amplitude variation and frequency of the pressure signals received from said arterial pressure sensor (112), calculate a parameter value based on said amplitude variation and said frequency, and issue an alarm if the parameter value exceeds a pre-set threshold value. Such detection aims at monitoring the occurrence of oscillating pressure signals. Such signals indicate an increased risk for hemolysis.

The present invention relates to a method and to an apparatus for preparing a dialysis solution, wherein the apparatus has a first circuit and a second circuit, wherein the first circuit has a container for receiving the consumed dialysis solution or fresh water or another fluid, the primary side of a filter connected downstream of the container, and a return line from the primary side of the filter into the container, wherein the filter is configured to prepare purified water from the consumed dialysis solution or from fresh water or from another fluid, and wherein the second circuit has the secondary side of the filter, the dialyzate side of a dialyzer, a reservoir, a line that leads from the reservoir to the secondary side of the filter, by means of which dialyzate or a dialyzate concentrate can be supplied to the secondary side of the filter, and a filtrate line that leads away from the secondary side of the filter.