Devices used to sense physiologic blood parameters are disclosed. The devices may be configured to sense at least two physiologic blood parameters at substantially a common site of an extracorporeal perfusion circuit. The devices may include a pressure sensor and a temperature sensor. The temperature sensor may be in direct contact with the blood.

Disclosed is an artificial heart and lung apparatus (100) that can be connected to a patient (P), and transfers removed blood to a human body via a roller pump (120), the system including: the roller pump (120); a blood removal line (101) which transfers removed blood to the roller pump (120); a first blood transfer line (104) that transfers blood, which is transferred from the roller pump (120), to the human body; a blood removal rate sensor (111) that is provided in the blood removal line (101); and a control unit (140), in which the control unit (140) performs control such that a blood transfer rate of the roller pump (120) is in a specific range with respect to a blood removal rate measured by a blood removal rate sensor (111).

Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and of cardiac and respiratory rates, and patient respiratory volume or effort.

A cannula for the drainage of blood vessels having a tubular body provided with a first and second ends, the second end being insertable inside a patient's blood vessel, and provided with at least one main channel extending between the ends, the tubular body being movable between a home configuration and an extended configuration, in which the diameter of said main channel is reduced with respect to the home configuration; an elastic part associated with said tubular body and adapted to counteract the displacement from the home configuration to the extended configuration; pressure detection part for detecting the pressure inside the blood vessel which are associated with the tubular body; wherein the pressure detection part comprise at least one pressure sensor associated with the tubular body in the proximity of the second end, and where the pressure sensor is arranged inside the main channel.

An extracorporeal circulation management device 10 displays an expected flow rate of blood flowing inside a circulation circuit 1R and an actual flow rate on a display unit 16, together with a standard pressure calculated based on the expected flow rate by referring to standard information representing a relation between the blood flow rate and a pressure loss occurring in each of devices 2, 5, and 6 provided in the circulation circuit 1R and stored in a storage unit, and an actual pressure related to each of the devices 2, 5, and 6, which is calculated based on an actual pressure measured by each of pressure measurement units 21, 22, and 23 as an actually measured value of a pressure of the blood flowing inside the circulation circuit 1R and the actual flow rate.

A monitoring device is included in a medical system to implement a method for prediction of a rapid symptomatic drop in a subject's blood pressure, e.g. during a medical treatment such as dialysis. To this aim, a pulse shape parameter (pPS) with respect to a pulse generator of the subject is registered by means of a pressure sensor arranged in an extracorporeal blood flow circuit coupled to a cardiovascular system of the subject (P). The pressure sensor is configured to detect pressure variations in blood vessels of the subject (P). It is investigated, during measurement period, whether or not one or more of the pulse shape parameters fulfil a decision criterion. An output signal (a) is generated if the decision criterion is found to be fulfilled, to indicate a predicted rapid symptomatic blood pressure decrease in the subject (P). The decision criterion may operate on pulse magnitude measures calculated for the received pulse shape parameters (pPS), or statistical dispersion measures calculated based on the thus-calculated pulse magnitude measures.

A system associated with a medical treatment device for detecting a condition of a patient includes an input device including at least a camera or a microphone. The system also includes a medical treatment device with a controller/classifier and at least one of flow controller, a pump, and/or an alarm output. The controller/classifier has at least a video-image processor or an audio processor configured to recognize a face and a body or to recognize changes in skin color, facial expression, or body position. The controller/classifier may also recognize speech and classify predefined normal and irregular sound patterns, and output state data corresponding thereto. The controller/classifier is connected to apply the state data to the at least one flow controller, pump, and/or alarm output.

A dialysis device for performing a dialysis treatment can include a liquid conducting system, which comprises a first section and a second section. A differential pressure sensor can be included for measuring a differential pressure p.sub.diffm between a first pressure (p.sub.1) in the first section of the liquid conducting system and a second pressure (p.sub.2) in the second section of the liquid conducting system. A monitoring unit is also provided, which is configured to determine an operating status based on the measured differential pressure p.sub.diffm. A control device is also provided, which is configured to interrupt and/or block the dialysis treatment according to the determined operating status. A display device is also provided, which is configured to output a notification based on the determined operating status.

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

A sorbent canister utilized when performing a dialysis treatment during hemodialysis (HD) or peritoneal dialysis (PD) is provided. The sorbent canister includes inlet and outlet ports that include a threaded interface for connection to inlet and outlet tubes for circulation of dialysate through the sorbent canister. Upon disconnection from a dialysis machine, a pressure relief cap can be threaded onto the threaded interface to seal the fluid in the sorbent canister while allowing for off-gases to be expelled when a pressure within the sorbent canister exceeds a threshold pressure, thereby preventing a rupture in the canister body. In one embodiment, the pressure relief cap includes a deformable insert with a hole formed therein that is closed in an uncompressed state and opened in a compressed state. In another embodiment, the pressure relief cap includes a diaphragm that mates with a feature of the inlet or outlet port.