Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

A percutaneous catheter provides an adjustable diameter in order to reduce pressure loss, maintain a required flow, and avoid increasing a load to the patient. A catheter tube is formed of braided wires in an intersecting manner and extends in an axial direction. A distal tip is affixed to a distal side of the catheter tube and is configured to engaged a distal end of a dilator. The catheter tube includes a non-coated portion on a proximal side of the distal tip and a coated portion embedded in a resin material. An inner diameter of the non-coated portion is larger than an outer diameter of the dilator. When the dilator is fully inserted through the percutaneous catheter, the non-coated portion expands in the axial direction, reducing its in inner diameter so that an inner surface of the non-coated portion comes into tight contact with an outer surface of the dilator.

A sorbent canister utilized when performing a dialysis treatment during hemodialysis (HD) or peritoneal dialysis (PD) is provided. The sorbent canister includes inlet and outlet ports that include a threaded interface for connection to inlet and outlet tubes for circulation of dialysate through the sorbent canister. Upon disconnection from a dialysis machine, a pressure relief cap can be threaded onto the threaded interface to seal the fluid in the sorbent canister while allowing for off-gases to be expelled when a pressure within the sorbent canister exceeds a threshold pressure, thereby preventing a rupture in the canister body. In one embodiment, the pressure relief cap includes a deformable insert with a hole formed therein that is closed in an uncompressed state and opened in a compressed state. In another embodiment, the pressure relief cap includes a diaphragm that mates with a feature of the inlet or outlet port.

The invention relates to a dialysis machine having an extracorporeal blood circuit, a blood pump, a dialyzer, a venous pressure sensor, a substituate line, and a control unit, wherein the control unit is configured to operate the blood pump in a first operating mode and in a special operating mode and to start the special operating mode after recognition of a trigger event, in which special operating mode a conveying rate of the blood pump is controlled by means of a default value or is regulated to a desired value, which default or desired value is derived from a value determined before the start of the currently started special operating mode or corresponds to said value, wherein the presence of at least one obstacle is polled before the start of the special operating mode, and wherein, on the presence of the obstacle, the start of the special operating mode is blocked or delayed and/or the selection of the default value or of the desire value on the presence of the obstacle differs from the selection without the presence of the obstacle.

This invention relates to dialysis systems and methods. In some implementations, a method includes applying vacuum pressure to a device of a dialysis system, and then determining, based on a detected fluid level or measured pressure, whether the device is functioning properly.

A device and method are used for monitoring an extracorporeal blood treatment device, such as a dialysis machine, which includes an extracorporeal blood circuit having an arterial blood line with an arterial patient port and/or at least one venous blood line with a venous patient port, and a dialysis fluid system which has a dialysis fluid supply line and a dialysis fluid drain line. The monitoring device selects and senses a measured value during operation of the extracorporeal blood treatment device which is suitable for monitoring the blood treatment device to compare a time-related actual course of the measured value with a target course of the measured value stored in a memory, and to determine that there is a defect if, at least in sections, the actual course of the measured value deviates from the target course by more than a defined tolerance.

Provided is a pressure gauge capable of being effectively used for internal pressure measurement of a balloon catheter and capable of providing easy monitoring of a pressure value even when measuring internal pressure of an extracorporeal circulation circuit. The pressure gauge measures internal pressure of a balloon catheter used for treatment and diagnosis or pressure of a body lumen of a living body and includes a coil-shaped tube 2 to elastically deform. One end of the tube 2 is set as an open fixed end and the other end is set as a sealed free end and pressure introduced from the open fixed end can be measured based on a displacement position of the tube 2 due to the pressure.

A fluid processing cassette and sensor coupling system is disclosed, comprising a cassette comprising a cap having an opening formed by an inner cylindrical wall having a first diameter, an outer cylindrical wall having a second diameter, and a contact surface connecting the inner and outer cylindrical walls. The contact surface includes a varying diameter that decreases from the second diameter to the first diameter. A sensor post comprises a ring disposed around a cylindrical body and is positioned to engage with the contact surface of the cap to form a seal.

A blood purification system that is capable of notifying any changes in the patient's condition on the basis of noninvasive vital sings of the patient that are observed during the blood purification treatment. An external information-processing apparatus includes an external input device into which a vital sign detected by a detecting device is inputtable in real time; a checking device capable of checking whether or not the vital sign inputted in real time into the external input device satisfies a predetermined condition; and an external output device capable of outputting, if it is determined by the checking device that the vital sign satisfies the predetermined condition, a result of the checking or checked information including the vital sign leading to the result of the checking to a blood purification apparatus. The checked information outputted from the external output device is displayable on a display included in the blood purification apparatus.

Dialysis systems and methods are described which can include a number of features. The dialysis systems described can be to provide dialysis therapy to a patient in the comfort of their own home. The dialysis system can be configured to prepare purified water from a tap water source in real-time that is used for creating a dialysate solution. The dialysis systems described also include features that make it easy for a patient to self-administer therapy.