The present invention relates to a method for filling a membrane filter of a blood treatment system, the blood treatment system comprising at least one blood treatment machine, a membrane filter, in particular a hollow fiber membrane filter, having a first and a second chamber which are semi-permeably separated by a membrane, and at least one first partial circuit and at least one second partial circuit. The first chamber of the membrane filter is arranged in the first partial circuit and the second chamber of the membrane filter is arranged in the second partial circuit. The first chamber of the membrane filter is filled with liquid via the first partial circuit, whilst the second chamber is still filled with air, and a pump is arranged in the first partial circuit upstream of the membrane filter. According to the invention,

A blood purification device 1 is provided with: a blood circuit 2 for extracorporeally circulating blood of a patient; a blood purifier 3 provided in the blood circuit 2; a gas-liquid separator 24 which is provided in the blood circuit 2 and located on the downward side of the blood purifier 3 in the direction of blood flow, and separates air bubbles contained in blood flowing thereinto; and a liquid surface adjustment unit 6 capable of adjusting the liquid level in the gas-liquid separator 24. The liquid surface adjustment unit 6 performs control such that the liquid level during priming is higher than the liquid level during treatment.

A plasmapheresis system and a method for operating a plasmapheresis system are provided by which the volume/weight of anticoagulated plasma that is collected is optimized. In one example, a nomogram is provided that utilizes the donor's hematocrit to calculate the volume/weight of raw plasma within a plasma product having the maximum volume permitted by the FDA nomogram. In a plasmapheresis procedure having multiple collection phases followed by a reinfusion cycle in which concentrated red blood cells are returned to the donor, the volume of plasma product to be collected is calculated prior to the start of each collection cycle to account for the donor's increasing hematocrit, thus resulting in a greater total volume of plasma product to be collected during the plasmapheresis procedure.

The present disclosure relates to a disposable, which comprises a fluid line and a connector having a connector lumen, for fluidically connecting the fluid line to a first lumen of a first fluid guide of a port, which further comprises a second lumen. It further relates to a system with a disposable according to the present disclosure and with a port for establishing a fluid communication between at least one fluid line of the treatment apparatus, which fluid line is assigned to the interior of a blood treatment apparatus, and a connector of a fluid line of a disposable, which fluid line is assigned to the exterior of the treatment apparatus.

A flushable catheter device has an outer tube with a first distal end opening to be introduced into a blood vessel and defining a first lumen. An inner tube is disposed in the first lumen with a second distal end opening proximally spaced from the first distal end opening and defining a second lumen. A space axially disposed between the end openings defines an outflow/inflow inhibiting portion which inhibits a flow of fluid out from the first lumen into the into the vessel as a result of a perfusion of a flushing fluid being supplied through the first lumen and into the second lumen.

Hemodialysis systems are described. A hemodialysis system may include a dialysate flow path through which dialysate is passed from a dialysate reservoir, which includes a valved vent to atmosphere, to an ultrafilter. The dialysate flow path includes a pneumatically actuated diaphragm-based dialysate pump for pumping fluid from the dialysate reservoir to the ultrafilter. The hemodialysis system may include a controller for controlling pneumatic actuation pressure delivered to the dialysate pump and at least one valve connecting the dialysate reservoir vent to the atmosphere. The hemodialysis system may be configured to actuate the dialysate pump and the at least one valve to introduce air into the dialysate flow path and expel liquid from the dialysate flow path to a drain.

Disclosed herein are devices and methods related to UV disinfection of a transfer catheter during peritoneal dialysis. The transfer catheter comprises a first and second end, the second end comprising a transfer valve. The transfer valve body comprises an inlet, outlet, and a flush hole. The valve core comprises a notch configured to allow fluid flow between the various flow paths. The valve core and body are positioned off axis with respect to the fluid flow path. The transfer catheter can allow for a small volume kill zone, which can minimize the amount of UV required to disinfect the catheter.

A renal failure therapy system includes a dialysis fluid circuit including a dialysis fluid pump; a source of physiological cleaning, disinfecting, and/or decalcifying substance in fluid communication with the dialysis fluid circuit; a source of purified water in fluid communication with the dialysis fluid circuit; and a logic implementer in operable communication with the dialysis fluid pump, the logic implementer causing the physiological cleaning, disinfecting, and/or decalcifying substance from its source to be added to purified water from the purified water source to form a mixture and to circulate the mixture within the dialysis fluid circuit using the dialysis fluid pump to at least one of clean, disinfect or decalcify at least a portion of the dialysis fluid circuit without a subsequent rinse.

A method and apparatus for priming an extracorporeal blood system. The extracorporeal blood system includes an arterial blood line, a venous blood line, a pump segment for interaction with a peristaltic blood pump of the apparatus and a blood treatment unit. A port of the venous blood line is connected to a venous blood port of the blood treatment unit. A port of the arterial blood line is connected to an arterial blood port of the blood treatment unit. The extracorporeal blood system is connected to a reservoir containing priming liquid. The non-occluded extracorporeal blood system is subsequently filled with priming liquid and, after filling with priming liquid, the pump segment is automatically occluded by a blood pump.

Simple-to-use systems, methods, and devices for priming replacement blood treatment devices, for swapping the blood treatment devices out, for replacing swapped-out blood treatment devices, and other related operations are described. In embodiments, a blood treatment device can be primed while a therapy is still running. When the replacement blood treatment device is needed, the therapy can be stopped momentarily (less than a minute) for the rapid and safe swap of the blood treatment device. Blood loss can be minimized. The down time from therapy can be minimized.