Patent classifications
H05H3/04
Multiple laminar flow-based particle and cellular separation with laser steering
The invention provides a method, apparatus and system for separating blood and other types of cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One of the exemplary methods includes providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.
Multiple laminar flow-based particle and cellular separation with laser steering
The invention provides a method, apparatus and system for separating blood and other types of cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One of the exemplary methods includes providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.
Multiple laminar flow-based particle and cellular separation with laser steering
The invention provides a method, apparatus and system for separating blood and other types of cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One of the exemplary methods includes providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.
Scalable, electro-optically induced force system and method
A technique is disclosed for electro-optically inducing a force to fabricated samples and/or devices with laser light. The technique uses the interaction of the oscillating electric field of the laser beam in opposition with the electric field produced by an appropriate electric charge carrier to achieve a net repulsive (or attractive) force on the component holding the electric charge. In one embodiment, force is achieved when the field near the charge carrier is modulated at a subharmonic of the electric field oscillation frequency of the laser and the relative phases of the light field and electric charge carrier field are controlled to provide optimal repulsion/attraction. The effect is scalable by applying the technique to an array of charge carrier fields sequentially as well as using higher power lasers and higher carrier field voltages.
Scalable, electro-optically induced force system and method
A technique is disclosed for electro-optically inducing a force to fabricated samples and/or devices with laser light. The technique uses the interaction of the oscillating electric field of the laser beam in opposition with the electric field produced by an appropriate electric charge carrier to achieve a net repulsive (or attractive) force on the component holding the electric charge. In one embodiment, force is achieved when the field near the charge carrier is modulated at a subharmonic of the electric field oscillation frequency of the laser and the relative phases of the light field and electric charge carrier field are controlled to provide optimal repulsion/attraction. The effect is scalable by applying the technique to an array of charge carrier fields sequentially as well as using higher power lasers and higher carrier field voltages.
DOWNHOLE NEUTRON GENERATORS AND METHODS TO AUTO TUNE DOWNHOLE NEUTRON GENERATORS
Downhole neutron generators, downhole logging tools that utilize neutron generators, and methods to auto tune downhole neutron generators are disclosed. While a neutron generator is deployed in a borehole of a wellbore, the method includes determining whether an oscillation cycle of an ion beam current generated by the neutron generator is stable. After a determination that the oscillation cycle of the ion beam current is stable, the method includes determining proportional, integral, and derivative parameters of a proportional-integral-derivative controller that is operable to adjust an amount of power supplied to generate ions. The method further includes adjusting a replenish voltage of a replenish power supply of the neutron generator based on the proportional, integral, and derivative parameters.
DOWNHOLE NEUTRON GENERATORS AND METHODS TO AUTO TUNE DOWNHOLE NEUTRON GENERATORS
Downhole neutron generators, downhole logging tools that utilize neutron generators, and methods to auto tune downhole neutron generators are disclosed. While a neutron generator is deployed in a borehole of a wellbore, the method includes determining whether an oscillation cycle of an ion beam current generated by the neutron generator is stable. After a determination that the oscillation cycle of the ion beam current is stable, the method includes determining proportional, integral, and derivative parameters of a proportional-integral-derivative controller that is operable to adjust an amount of power supplied to generate ions. The method further includes adjusting a replenish voltage of a replenish power supply of the neutron generator based on the proportional, integral, and derivative parameters.
MULTIPLE LAMINAR FLOW-BASED PARTICLE AND CELLULAR SEPARATION WITH LASER STEERING
The invention provides a method, apparatus and system for separating blood and other types of cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One of the exemplary methods includes providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.
MULTIPLE LAMINAR FLOW-BASED PARTICLE AND CELLULAR SEPARATION WITH LASER STEERING
The invention provides a method, apparatus and system for separating blood and other types of cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One of the exemplary methods includes providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.
Neutron generator with a rotating target in a vacuum chamber
A portable neutron generator is provided that does not utilize liquid cooling. The portable neutron generator includes a vacuum chamber housing defining a vacuum chamber and an ion beam inlet. The portable neutron generator also includes a rotating target positioned within the vacuum chamber. The ion beam inlet is oriented to receive ions such that the ions impinge upon the rotating target to cause neutrons to be emitted. The rotating target comprises a copper alloy. The portable neutron generator also includes a motor core positioned within the vacuum chamber and coupled to the rotating target. A motor stator is electromagnetically coupled with the motor core. The motor core is configured to rotate the rotating target at greater than 200 Hz during operation.