Disclosed herein is a bidirectional intravascular cannula, or catheter, that is configured to provide and return blood in a patient bidirectionally. The bidirectional intravascular cannula is configured to reduce or obviate the need for a second cannula, such as currently available unidirectional cannulae, to be placed in a second or opposite direction of flow. Users would include cardiac surgeons, intensivists, vascular surgeons, ER doctors, IR doctors and cardiologist who use peripheral cannulation for ECLS or cardiopulmonary bypass. The cannula allows continued flow to a patient's limb even with the cannula proximally in the vessel. The cannula further allows larger size cannula to be placed without the need for additional distal catheter placement.

A method for determining water losses in a membrane gas exchanger of an apparatus for extracorporeal treatment of blood, comprises: obtaining a sweep gas flow rate (Q.sub.gas) in a gas side of a membrane gas exchanger (19); obtaining a water saturation content (C.sub.saturation_out) at a gas outlet (19d) of the membrane gas exchanger (19); calculating the water losses (Q.sub.eccor) as a function at least of the sweep gas flow rate (Q.sub.gas) and the water saturation content (C.sub.saturation_out).

The present invention relates to a system (100) for extracorporeal blood treatment comprising a first inlet (1) for introducing a bloodstream to be treated into the system (100), three blood treatment apparatus (A, D, G), as well as an outlet (2) for discharging a treated bloodstream from the system (100), wherein the system comprises an adsorber apparatus (A) and/or a plasma separator apparatus, a dialysis apparatus (D) and a gas exchange apparatus (G), and wherein the three blood treatment apparatus (A, D, G) are sequentially connected in series in a functional state of system (100) application between the inlet (1) and the outlet (2) of the system relative to a direction of blood flow of a bloodstream to be treated and can be consecutively perfused extracorporeally by a bloodstream to be treated. The present invention further relates to a treatment apparatus comprising such a system, a kit comprising the components of such a system, a method for operating such a system (100) as well as a method for extracorporeal blood treatment with such a system (100).

A system for heating/cooling a target unit. The system including a heater/cooler unit and a heat transfer fluid module. The heater/cooler unit including a heater/cooler that includes a heater/cooler element and a heater/cooler pump, and a heat exchanger that includes a heat exchange element. Where, the heater/cooler pump pumps a first fluid through the heater/cooler element and the heat exchange element and back to the heater/cooler pump. The heat transfer fluid module including a fluid reservoir with a second fluid that is pumped to and through the heat exchanger to transfer heating/cooling between the first fluid and the second fluid and pumped to and through the target unit to transfer heating/cooling between the second fluid and the target unit.

Disclosed is a cannula to be used in open heart surgery to connect the patient to the heart-lung machine reliably and quickly by extra thoracic cannulation.

A blood treatment system includes (i) a blood pump including a first blood pump chamber operable with a first inlet valve and a first outlet valve, and a second blood pump chamber operable with a second inlet valve and a second outlet valve; (ii) an arterial blood line; (iii) a dialyzer placed in fluid communication with the arterial blood line, wherein the blood pump is provided along the arterial blood line upstream of the dialyzer; and (iv) a venous blood line extending downstream from the dialyzer. The system also includes a processor configured to sequence the first and second blood pump chambers so as to achieve a pulsatile pattern of filling the first and second blood pump chambers and an at least substantially constant pattern of discharging blood from the first and second blood pump chambers to the dialyzer.

A blood reservoir may be used in combination with other elements such as a heart lung machine (HLM), oxygenator, heat exchanger, arterial filter and the like to form an extracorporeal blood circuit that may be employed in a procedure such as a bypass procedure. The blood reservoir may be configured to receive, filter and store blood from a number of sources including vent blood (from within the heart), venous blood (from a major vein), purge blood (from a sampling line) and cardiotomy or suction blood (from the surgical field).

A pulmonary artery (PA) via trans-septal to left atrial (LA) percutaneous dual lumen cannulation system which reduce the pressure of the right ventricle provides drainage of pulmonary artery blood with bypassing the lung while return the blood to the Left Atrium (LA) without the need for thoracotomy for a wearable pump less extra corporeal lung assist (pECLA) to remove CO.sub.2, pump less extra corporeal membrane oxygenation (ECMO), para-corporeal pump driven CO.sub.2 removal, extra corporeal CO.sub.2 removal (ECCO.sub.2R) pump driven, para-corporeal pump driven membrane oxygenation, or extra corporeal membrane oxygenation (ECMO) with extra-corporeal pump. By establishing percutaneously a shunt with a dual lumen cannula between PA and LA using the PA-LA pressure gradient as the driving force for the blood flow through the drainage lumen, CO.sub.2 removal device, or oxygenator and return cannula lumen in the vascular system.

An extracorporeal life support device control system and method arranged to provide suitable gas and blood flow rates through an extracorporeal life support device. The control system comprises: a sensor arranged to detect and output a measurand, wherein the measurand is characteristic of a single autonomic nervous system output defining a metabolic demand; and a controller arranged to receive the measurand, and further arranged to control, according to the measurand: gas and/or liquid flow rates through an extracorporeal life support device; wherein the flow rates are arranged to provide blood gas concentrations similar to those arising from healthy lungs at the metabolic demand. In the case of patients with healthy lungs, the control system can control the blood flow rate without controlling gas flow rates through an oxygenator.

A dual lumen drainage cannula configured for use in a VA ECMO system includes a first drainage tube having a proximal end, a distal end, and at least one aperture in at least one wall of the first drainage tube proximate to the distal end of the first drainage tube, and a second drainage tube having a proximal end, a distal end, and at least one aperture in at least one wall of the second drainage tube proximate to the distal end of the second drainage tube. The first drainage tube passes through the second drainage tube. The dual lumen drainage cannula also includes a sleeve positioned adjacent to an interior wall of the second drainage tube. The sleeve is formed of a flexible material so as to be expandable and collapsible within the second drainage tube.