A minimally invasive neutron beam generating device is provided. The minimally invasive neutron beam generating device includes a proton accelerator, a target, and a neutron moderator. The proton accelerator is connected to a first channel, the target is located at one end of the first channel, and the neutron moderator covers the end of the first channel so that the target is embedded in the neutron moderator. In addition, the neutron moderator includes an accommodating element for accommodating a moderating substance, and the accommodating element is retractable.

Apparatus (1) for generating neutrons comprising a hollow casing (2) having a central axis (A) and configured for rotating about said central axis (A), said hollow casing (A) comprising a wall (3) having a central region (3a), substantially at the central axis (A) and a peripheral region (3b) external to said central region (3a), said wall (3) defining a cavity (4), said cavity (4) being configured for containing a first coolant fluid; an active layer (6) positioned at least partially on said peripheral region (3b) externally to said cavity (4), said active layer (6) being configured for realizing a neutron-generating reaction; at least a particle accelerator (7) configured for directing a ion beam on said active layer (6) for activating said reaction; movement means (8) configured for rotating said hollow casing (2) about said central axis (A) forcing said first coolant fluid to lightly touch internally said wall (3) at said active layer (6) for cooling said hollow casing (2); external cooling means (9) configured for externally cooling the hollow casing (2), said external cooling means (9) comprising a second coolant fluid lightly touching externally at least partially said wall (3). Said hollow casing (2) is sealed with respect to an external environment for retaining said first coolant fluid inside said cavity (4).

Apparatus (1) for generating neutrons comprising a hollow casing (2) having a central axis (A) and configured for rotating about said central axis (A), said hollow casing (A) comprising a wall (3) having a central region (3a), substantially at the central axis (A) and a peripheral region (3b) external to said central region (3a), said wall (3) defining a cavity (4), said cavity (4) being configured for containing a first coolant fluid; an active layer (6) positioned at least partially on said peripheral region (3b) externally to said cavity (4), said active layer (6) being configured for realizing a neutron-generating reaction; at least a particle accelerator (7) configured for directing a ion beam on said active layer (6) for activating said reaction; movement means (8) configured for rotating said hollow casing (2) about said central axis (A) forcing said first coolant fluid to lightly touch internally said wall (3) at said active layer (6) for cooling said hollow casing (2); external cooling means (9) configured for externally cooling the hollow casing (2), said external cooling means (9) comprising a second coolant fluid lightly touching externally at least partially said wall (3). Said hollow casing (2) is sealed with respect to an external environment for retaining said first coolant fluid inside said cavity (4).

Apparatuses and methods for producing neutrons for applications such as boron neutron capture therapy (BNCT) are described. An apparatus can include a rotary fixture with a coolant inlet and a coolant outlet, and a plurality of neutron-producing segments. Each neutron-producing segment of the plurality of neutron-producing segments is removably coupled to the rotary fixture, and includes a substrate having a coolant channel circuit defined therein and a solid neutron source layer disposed thereon. The coolant channel circuits are in fluid communication with the coolant inlet and the coolant outlet.

Apparatuses and methods for producing neutrons for applications such as boron neutron capture therapy (BNCT) are described. An apparatus can include a rotary fixture with a coolant inlet and a coolant outlet, and a plurality of neutron-producing segments. Each neutron-producing segment of the plurality of neutron-producing segments is removably coupled to the rotary fixture, and includes a substrate having a coolant channel circuit defined therein and a solid neutron source layer disposed thereon. The coolant channel circuits are in fluid communication with the coolant inlet and the coolant outlet.

A neutron capture therapy system includes an accelerator for accelerating charged particles to generate a charged particle beam, a beam transmitting device, and a neutron beam generating device. The neutron beam generating device further includes a first, a second and a third neutron beam generating device. The beam transmitting device further includes a first transmitting device connected to the accelerator, a beam direction conversion device configured to switch a traveling direction of the charged particle beam, and a second, a third and a fourth transmitting device that respectively transmit the charged particle beam from the beam direction conversion device to the first, the second and the third neutron beam generating device, wherein two of the first, the third and the fourth transmitting device define a first plane, a first and a second transmitting device define a second plane, and the first plane is different from the second plane.

A filter is provided. The filter includes a mixed layer. The mixed layer includes aluminum, magnesium fluoride, and lithium fluoride. The mixed layer is composed of 1 part by volume of magnesium fluoride, 0.25 to 1 parts by volume of aluminum, and 0.003 to 0.02 parts by volume of lithium fluoride.

A filter is provided. The filter includes a mixed layer. The mixed layer includes aluminum, magnesium fluoride, and lithium fluoride. The mixed layer is composed of 1 part by volume of magnesium fluoride, 0.25 to 1 parts by volume of aluminum, and 0.003 to 0.02 parts by volume of lithium fluoride.

Provided herein are neutron imaging systems (e.g., radiography and tomography) systems and methods that provide, for example, high-quality, high throughput 2D and 3D fast or thermal neutron and/or X-ray images. Such systems and methods find use for the commercial-scale imaging of industrial components. In certain embodiments, provided herein are system comprising a plurality of independent neutron absorber-lined collimators (e.g., 4 or more collimators) extending outwards from a central neutron source assembly.

Provided herein are neutron imaging systems (e.g., radiography and tomography) systems and methods that provide, for example, high-quality, high throughput 2D and 3D fast or thermal neutron and/or X-ray images. Such systems and methods find use for the commercial-scale imaging of industrial components. In certain embodiments, provided herein are system comprising a plurality of independent neutron absorber-lined collimators (e.g., 4 or more collimators) extending outwards from a central neutron source assembly.