To provide a functional membrane for ion beam transmission capable of enhancing ion beam transmittance and improving beam emittance. A functional membrane for ion beam transmission according to the present invention is used in a beam line device through which an ion beam traveling in one direction passes and has a channel. The axis of the channel is substantially parallel to the travel direction of the ion beam.

Described are devices, systems, and methods for modulating the spectral energy distribution produced by an x-ray source via control of the energy of the x-ray-generating electron beam, e.g., for energy-modulated radiation therapy or other purposes. In some embodiments, such energy modulation is achieved by an add-on device to a linear accelerator. Also disclosed are computational methods and computer program products for planning energy-modulated therapy.

Described are devices, systems, and methods for modulating the spectral energy distribution produced by an x-ray source via control of the energy of the x-ray-generating electron beam, e.g., for energy-modulated radiation therapy or other purposes. In some embodiments, such energy modulation is achieved by an add-on device to a linear accelerator. Also disclosed are computational methods and computer program products for planning energy-modulated therapy.

Method includes providing a substrate layer, depositing a first layer along an exposed side of the substrate layer, and depositing a second layer along an exposed side of the first layer such that the first layer is disposed between the substrate layer and the second layer. One of the first or second layers is a backing layer and the other is a conductive layer. The first and second layers form a stripping sheet that is configured to strip electrons from charged particles passing through the stripping sheet. The method also includes removing at least a portion of the substrate layer.

Method includes providing a substrate layer, depositing a first layer along an exposed side of the substrate layer, and depositing a second layer along an exposed side of the first layer such that the first layer is disposed between the substrate layer and the second layer. One of the first or second layers is a backing layer and the other is a conductive layer. The first and second layers form a stripping sheet that is configured to strip electrons from charged particles passing through the stripping sheet. The method also includes removing at least a portion of the substrate layer.

System includes a particle accelerator configured to direct a particle beam of charged particles along a designated path. The system also includes an extraction device positioned downstream from the particle accelerator. The extraction device includes a stripper foil and a foil holder that holds the stripper foil. The foil holder is configured to position the stripper foil across the designated path of the particle beam such that the particle beam is incident thereon. The stripper foil is configured to remove electrons from the charged particles, wherein the stripper foil includes a backing layer and a conductive layer stacked with respect to one another. The backing layer includes synthetic diamond.

System includes a particle accelerator configured to direct a particle beam of charged particles along a designated path. The system also includes an extraction device positioned downstream from the particle accelerator. The extraction device includes a stripper foil and a foil holder that holds the stripper foil. The foil holder is configured to position the stripper foil across the designated path of the particle beam such that the particle beam is incident thereon. The stripper foil is configured to remove electrons from the charged particles, wherein the stripper foil includes a backing layer and a conductive layer stacked with respect to one another. The backing layer includes synthetic diamond.

In various embodiments, a radiation therapy system can include a cyclotron that outputs a charged particle beam. In addition, the radiation therapy system can include an apparatus to receive the charged particle beam from the cyclotron. The apparatus decelerates or further accelerates the charged particle beam to produce a reduced or increased energy charged particle beam. The apparatus can include a radio frequency structure.

In various embodiments, a radiation therapy system can include a cyclotron that outputs a charged particle beam. In addition, the radiation therapy system can include an apparatus to receive the charged particle beam from the cyclotron. The apparatus decelerates or further accelerates the charged particle beam to produce a reduced or increased energy charged particle beam. The apparatus can include a radio frequency structure.

A proton beam imaging system includes: a proton beam generator to generate a proton beam; a proton beam modulator through which the proton beam passes positioned between the proton beam generator and an image target; and a proton beam detector positioned to detect the proton beam existing the image target; wherein the proton beam modulator comprises: a rotating wheel having an axis of rotation positioned so that the proton beam passes through the axis of rotation and the axis of rotation is perpendicular to the proton beam; a first modulating portion comprising a first material portion and a second material portion through which a proton beam passes; and a second modulating portion comprising a third material portion and a fourth material portion through with the proton beam passes; wherein the first and second wedges are positioned opposite each other on the rotating wheel.