An example particle therapy system includes: a synchrocyclotron to output a particle beam; a magnet to affect a direction of the particle beam to scan the particle beam across at least part of an irradiation target; scattering material that is configurable to change a spot size of the particle beam, where the scattering material is down-beam of the magnet relative to the synchrocyclotron; and a degrader to change an energy of the beam prior to output of the particle beam to the irradiation target, where the degrader is down-beam of the scattering material relative to the synchrocyclotron.

Radio-frequency (RF) electrode for a cyclotron. The RF electrode includes a hollowed dee having first and second surfaces that oppose each other and define a gap therebetween. The hollowed dee is configured to be electrically controlled to direct a beam of charged particles through the gap and along an orbit plane of the cyclotron. The orbit plane extends parallel to the first and second surfaces through the gap. The RF electrode also includes a bridge structure that is coupled to and extends away from the hollowed dee. The bridge structure includes a side wall that defines an interior cavity of the bridge structure. The side wall has a particle opening therethrough that coincides with or is proximate to the orbit plane such that the particle opening receives neutral particles from an orbit of the charged particles.

Radio-frequency (RF) electrode for a cyclotron. The RF electrode includes a hollowed dee having first and second surfaces that oppose each other and define a gap therebetween. The hollowed dee is configured to be electrically controlled to direct a beam of charged particles through the gap and along an orbit plane of the cyclotron. The orbit plane extends parallel to the first and second surfaces through the gap. The RF electrode also includes a bridge structure that is coupled to and extends away from the hollowed dee. The bridge structure includes a side wall that defines an interior cavity of the bridge structure. The side wall has a particle opening therethrough that coincides with or is proximate to the orbit plane such that the particle opening receives neutral particles from an orbit of the charged particles.

A high gradient linear accelerating structure can propagate high frequency waves at a negative harmonic to accelerate low-energy ions. The linear accelerating structure can provide a gradient of 50 MV/m for particles at a of between 0.3 and 0.4. The high gradient structure can be a part of a linear accelerator configured to provide an energy range from an ion source to 450 MeV/u for .sup.12C.sup.6+ and 250 MeV for protons. The linear accelerator can include one or more of the following sections: a radiofrequency quadrupole (RFQ) accelerator operating at the sub-harmonic of the S-band frequency, a high gradient structure for the energy range from 45 MeV/u to 450 MeV/u.

A high gradient linear accelerating structure can propagate high frequency waves at a negative harmonic to accelerate low-energy ions. The linear accelerating structure can provide a gradient of 50 MV/m for particles at a of between 0.3 and 0.4. The high gradient structure can be a part of a linear accelerator configured to provide an energy range from an ion source to 450 MeV/u for .sup.12C.sup.6+ and 250 MeV for protons. The linear accelerator can include one or more of the following sections: a radiofrequency quadrupole (RFQ) accelerator operating at the sub-harmonic of the S-band frequency, a high gradient structure for the energy range from 45 MeV/u to 450 MeV/u.

Radio-frequency (RF) electrode for a cyclotron. The RF electrode includes a hollowed dee having first and second surfaces that oppose each other and define a gap therebetween. The hollowed dee is configured to be electrically controlled to direct a beam of charged particles through the gap and along an orbit plane of the cyclotron. The orbit plane extends parallel to the first and second surfaces through the gap. The RF electrode also includes a bridge structure that is coupled to and extends away from the hollowed dee. The bridge structure includes a side wall that defines an interior cavity of the bridge structure. The side wall has a particle opening therethrough that coincides with or is proximate to the orbit plane such that the particle opening receives neutral particles from an orbit of the charged particles.

Radio-frequency (RF) electrode for a cyclotron. The RF electrode includes a hollowed dee having first and second surfaces that oppose each other and define a gap therebetween. The hollowed dee is configured to be electrically controlled to direct a beam of charged particles through the gap and along an orbit plane of the cyclotron. The orbit plane extends parallel to the first and second surfaces through the gap. The RF electrode also includes a bridge structure that is coupled to and extends away from the hollowed dee. The bridge structure includes a side wall that defines an interior cavity of the bridge structure. The side wall has a particle opening therethrough that coincides with or is proximate to the orbit plane such that the particle opening receives neutral particles from an orbit of the charged particles.

A device controller controls an acceleration-related devices and an extraction-related devices of an accelerator for accelerating and extracting a particle beam, in such a way that the controller checks, at a time point when receiving a master clock pulse, that preparation for operating the acceleration-related devices is completed and then commands the acceleration-related devices to operate in accordance with an operation pattern corresponding to a prescribed energy of the particle beam, and commands the acceleration-related devices to operate in accordance with an extracting operation pattern when an extraction enable signal indicating that the particle beam reaches the prescribed energy is turned ON and an extraction-related device setting-status signal indicating that completion of setting the extraction-related devices for the prescribed energy is ON.

A device controller controls an acceleration-related devices and an extraction-related devices of an accelerator for accelerating and extracting a particle beam, in such a way that the controller checks, at a time point when receiving a master clock pulse, that preparation for operating the acceleration-related devices is completed and then commands the acceleration-related devices to operate in accordance with an operation pattern corresponding to a prescribed energy of the particle beam, and commands the acceleration-related devices to operate in accordance with an extracting operation pattern when an extraction enable signal indicating that the particle beam reaches the prescribed energy is turned ON and an extraction-related device setting-status signal indicating that completion of setting the extraction-related devices for the prescribed energy is ON.

The invention comprises a multi-axis charged particle irradiation method and apparatus. The multi-axis controls includes separate or independent control of one or more of horizontal position, vertical position, energy control, and intensity control of the charged particle irradiation beam. Optionally, the charged particle beam is additionally controlled in terms of timing. Timing is coordinated with patient respiration and/or patient rotational positioning. Combined, the system allows multi-axis and multi-field charged particle irradiation of tumors yielding precise and accurate irradiation dosages to a tumor with distribution of harmful proximal distal energy about the tumor.