Diffusion and infusion resistant implantable devices and methods for reducing pulsatile pressure are provided. The implantable device includes a balloon implantable within a blood vessel of a patient, e.g., the pulmonary artery. The balloon is injected with a fluid mixture comprising a constituent fluid(s) and a diffusion-resistant gas to provide optimal balloon volume and limit fluid diffusion throughout multiple cardiac cycles. The fluid mixture may be pressurized such that the balloon is transitionable between an expanded state and a collapsed state responsive to pressure fluctuations in the blood vessel.

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (PRP) and or platelet poor plasma (PPP) can be obtained rapidly and is ready for immediate injection into the host. Embodiments may include valves, operated manually or automatically, to open ports that discharge the excess red blood cells and the excess plasma into separate receivers while retaining the platelets and other factors in the centrifuge chamber. High speeds used allow simple and small embodiments to be used at the patient's side during surgical procedures. The embodiments can also be used for the separation of liquids or slurries in other fields such as, for example, the separation of pigments or lubricants.

A collection bottle includes a lid and a canister. The canister has a closed end and an opened end and defines an interior space. The lid includes a lid body having a first side and a second side, a shield handle, and one or more ports. The first side of the lid body is configured to be coupled to the open end of the body to close the interior space. The shield handle and the one or more ports extend from the second side of the lid body. The shield handle extends a first distance from the second side of the lid body. The one or more ports extend a second distance from the second side of the lid body. The first distance is greater than the first distance.

A separation assembly for an apheresis system includes a first media bag, a second media mag, a vessel, and a separation set. The first media bag contains a first fluid medium. The second media bag contains a second fluid medium. The vessel is configured to contain a third fluid medium. The separation set includes a first tube and a second tube. The first tube has a first fitting that is configured to be coupled to the first media bag. The first tube defines a first length. The second tube has a second fitting that is configured to be coupled to the second media bag. The second tube defines a second length different from the first length. The separation set may further includes a third tube is configured to be coupled to the vessel.

A method includes receiving, with an apheresis system, data associated with a donor; determining, based on the data associated with a donor, an identification of the donor; receiving, with the apheresis system, data associated with a blood component collection set; receiving, with the apheresis system, data associated with a plasma collection bottle; and performing, with the apheresis system, a plasma donation process based on the identification of the donor, the data associated with the blood component set, and the data associated with the plasma collection bottle. Receiving the data associated with the donor may include scanning, with a scanner, an image. The scanner is disposed on the apheresis system and the image may include one of a one-dimensional barcode or a two-dimensional barcode. The data associated with the donor may be displayed on a user device.

A method includes detecting a condition including one or more of a change in flow of a fluid and a change in a composition of the fluid, issuing an alarm in response to the condition detected, lowering a flow rate; and attempting to restart process and increase the flow rate. The change in flow may include a change in pressure. The change in flow may be associated with a collapsed vein. The change in flow of the fluid may include detecting that the flow rate has fallen below a threshold. The change in the composition may be associated with a color. The change in the composition may include using a color sensor to detect one or more of a red, a green, and a blue reflection or transmission to detect red blood cells.

An apheresis system at least partially defines a chamber and includes centrifuge that is movable between lock and unlock states. The centrifuge includes a base, cover, lock assembly, and latch assembly. The cover engages the base and defines slots. The lock assembly is coupled to the base and rotates between latched and unlatched states. The lock assembly includes tabs and a protrusion. The tabs are in the slots of the cover. The protrusion at least partially defines a receptacle. The latch assembly is coupled to the base and includes a lever and engagement component attached thereto. In the latched state, the protrusion engages the engagement component to reduce or prevent rotation of the lock assembly. In the unlatched state, the lock assembly can rotate. In the lock state, the tabs are at least partially within the slots. In the unlock state, the cover is movable with respect to the base.

A modular serviceability sled includes a frame, subassembly, interconnection, gasket, and shielding component. The interconnection is operatively connected to the subassembly and includes an electrical, pneumatic, and/or hydraulic connection. The gasket can engage the frame and a base assembly of an apparatus. The shielding component can contact the frame and the base assembly and includes an electromagnetic interference and/or radio frequency shielding component. The sled is movable between an engaged state and a disengaged state. In the engaged state, the sled is at least partially within a receiving space of the apparatus, the gasket engages the frame and the base assembly, the shielding component contacts the frame and the base assembly, and the interconnection is operatively connected to a machine interconnection of the apparatus. In the disengaged state, the interconnection is disconnected from the machine interconnection and the sled is configured to freely move with respect to the base assembly.

A pump for fluids includes a rotor sub-assembly, a tubing pressure block, an inlet guide, an outlet guide, and a tubing guard. The rotor sub-assembly includes at least one roller. The tubing pressure block includes a raceway and at least one projection. The tubing pressure block is movable between a first position and a second position. The inlet guide includes an inlet tubing channel and is disposed proximate to a first side of the tubing pressure block. The outlet guide includes an outlet tubing channel and is disposed proximate to a second side of the tubing pressure block. The tubing guard is configured to engage with the inlet guide and the outlet guide when the tubing guard is in a closed position and is configured to expose the rotor sub-assembly, the tubing pressure block, the inlet guide, and the outlet guide when in an open position.