An aspiration catheter is provided including a proximal section and a distal section extendable through the proximal section. A vacuum transfer tool may be coupled to a proximal end of the proximal section. The vacuum transfer tool may include a proximal transfer tube and a distal transfer tube, each having an aspiration port in communication with a vacuum source. The proximal transfer tube may be removably received within a proximal end of the distal transfer tube. The distal section of the catheter may be inserted into the proximal section through the proximal transfer tube. The proximal transfer tube may maintain a vacuum around the proximal end of the distal section of the catheter such that when the distal section is removed by decoupling the proximal and distal transfer tubes, the vacuum within the distal transfer tube and proximal section of the catheter is maintained, preventing the escape of any clots.

A system for removing occlusive clot from a blood vessel comprises a catheter and an apparatus for generating a pulsatile vacuum force to pulse the pressure gradient at a distal end of the catheter. The pulse generator may be integral with or separate from the vacuum pump. The pulse generator may be applied to a flexible tubing between the vacuum pump and the proximal end of the catheter.

Negative pressure wound therapy apparatuses and dressings, and systems and methods for operating such apparatuses for use with dressings are disclosed. In some embodiments, controlling the delivery of therapy can be based on monitoring and detecting various operating conditions. An apparatus can have a controller configured to monitor the duty cycle of a source of negative pressure and, based on the monitored duty cycle, determine whether a leak is present. The controller can be configured to provide an indication that a leak is present. For example, the controller can be configured to suspend and/or pause the delivery of therapy, and to restart the delivery of therapy due to a timeout, request from a user, etc. In addition, the controller can be configured to pause and/or restart the delivery of therapy upon a request from the user, such as in response to the user operating a switch.

A surgical cassette for an ophthalmic surgical system includes an irrigation system, an aspiration system, and a computer. The irrigation system is in fluid communication with a handpiece and carries fluid toward a surgical site. The aspiration system is in fluid communication with the handpiece via an aspiration conduit and carries fluid away from the surgical site. The computer instructs the aspiration system to vibrate fluid back and forth within the aspiration conduit to perform a priming procedure.

A surgical cassette for an ophthalmic surgical system includes an irrigation system and an aspiration system. The irrigation system is in fluid communication with a handpiece and carries fluid toward a surgical site. The aspiration system is in fluid communication with the handpiece and carries fluid away from the surgical site. The aspiration system includes an aspiration pump and tubing of an aspiration conduit. The aspiration pump generates a normal vacuum pressure within the aspiration conduit to carry fluid away from the surgical site during normal operation. The tubing has a larger cross-sectional area in response to normal vacuum pressure. The tubing collapses from the larger cross-sectional area to a smaller cross-sectional area in response to an occlusion; maintains the smaller cross-sectional area during a post-occlusion break surge to mitigate the post-occlusion break surge; and returns to the larger cross-sectional area after the post-occlusion break surge.

A surgical cassette for an ophthalmic surgical system comprises an irrigation system and an aspiration system. The irrigation system is in fluid communication with a handpiece and carries fluid toward a surgical site. The aspiration system is in fluid communication with the handpiece via an aspiration conduit, and carries fluid away from the surgical site. The aspiration system comprises a chamber that expands to store fluid, and collapses to move the fluid to meet a volume demand in the aspiration conduit to mitigate a post-occlusion break surge.

Systems and methods for dynamically modulating aspiration in response to sensed conditions. An aspiration system can include a catheter configured to be inserted within a vasculature of the subject, a canister coupled to the catheter, a pressure source that generates a vacuum pressure through the catheter for aspirating the fluid, a sensor configured to sense a parameter associated with at least one of the catheter, the canister, or the pressure source, and a computer system coupled to the sensor. The computer can cause the pressure source to initiate the vacuum pressure throughout the catheter, receive a measurement of the parameter from the sensor, determine whether the measurement violates a threshold associated with the parameter, and modulate the vacuum pressure at the catheter tip in response to a determination that the measurement violates the threshold.

Systems and methods for controlling a pump system for use in negative pressure wound therapy are described herein. In some embodiments, a method for controlling a pump system includes applying a drive signal to a pump assembly of the pump system, the drive signal alternating between a positive amplitude and a negative amplitude and the drive signal having an offset, and sampling a pressure within a fluid flow path configured to connect the pump system to a wound dressing configured to be placed over a wound during one or more time intervals. Each of the one or more time intervals can occur when the drive signal is approximately at an amplitude equal to one or more sampling amplitudes.

A system for controlling aspiration of a phacoemulsification probe inserted into an eye includes an anti-vacuum surge (AVS) module, one or more sensors, a vacuum relief valve, and a processor. The AVS module is coupled with an aspiration channel of the probe and is configured to mitigate vacuum surges in the channel by regulating flow via the channel. The one or more sensors are configured to measure fluid parameters in the channel. The vacuum relief valve, which is fluidly coupled with the channel, is configured to controllably relieve vacuum in the channel. The processor is configured to identify a change in at least one of the fluid parameters by reading at least one of the one or more sensors, and, responsively to an identified change in fluid parameters, operate the vacuum relief valve using pulse width modulation (PWM) to maintain a pressure in the channel within a predefined range.

Methods of assembling a manifold for a medical waste collection system. A flapper valve unit is secured to a head of a cap. A filter element is positioned within a shell. Basket hands of the filter element are fitted between first pairs of ribs of the cap skirt. Fingers of the shell are fitted between second pairs of ribs of the cap skirt. The cap is secured to the shell to cover an open distal end of the shell. A drip stop is secured to the proximal end base of the shell to seat within the outlet opening. Ears may be fitted through holes defined by the flapper valve unit and cap holes defined by the cap so as to snap lock to the head of the cap. The hub of the flapper valve unit may be compressed with the ears snap locked to the head of the cap.