A system is illustratively described herein that generally comprises a vacuum chamber, an ambient pressure chamber, a valve configured for unidirectional flow from the vacuum chamber to the ambient pressure chamber during a charging stroke, and a liquid filter configured to retain liquid in the pump. In some embodiments, the liquid filter is configured to retain liquid in the vacuum chamber during the charging stroke. In other embodiments, it may be configured to retain liquid in the ambient pressure chamber during an operating stroke. In more particular embodiments, a piston may be disposed between the vacuum chamber and the ambient pressure chamber, a passage may fluidly couple the vacuum chamber and the ambient pressure chamber, and the valve can be configured to control fluid flow through the passage. Additionally, a lumen may couple the vacuum chamber to a dressing to deliver negative pressure to the dressing in some illustrative embodiments.

Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, positioning a distal portion of a catheter proximate to the clot material within the blood vessel. The method can further include coupling a pressure source to the catheter via a tubing subsystem including a valve or other fluid control device and, while the valve is closed, activating the pressure source to charge a vacuum. The valve can then be opened to apply the vacuum to the catheter to thereby aspirate at least a portion of the clot material from the blood vessel and into the catheter.

Provided is a medical aspirator including a hollow cylinder housing having a space therein, a piston slidable inside the cylinder housing in a longitudinal direction, and an elastic member having one end connected to the piston and the other end fixed to the cylinder housing, and allowing the piston to move in the longitudinal direction with a constant force, in which after the medical aspirator is installed in a surgical site, a constant suction pressure is maintained, so that side effects and accidents such as organ adhesion and tissue damage in a surgical site, resulting from an excessive pressure, are reduced, and body fluid in the surgical site is effectively discharged, so that the medical aspirator may contribute to shortening of a recovery period of a patient. Further, the present disclosure relates to a medical aspirator including an upper housing constituting an upper body, a lower housing constituting a lower body, a sealing film coupled along outer surfaces of the upper housing and the lower housing and having a space formed in the sealing film, and a screw thread connector connecting the upper housing and the lower housing and having a screw thread, in which after the medical aspirator is installed in a surgical site, a constant suction pressure is maintained, so that side effects and accidents such as organ adhesion and tissue damage in a surgical site, resulting from an excessive pressure, are reduced, and body fluid in the surgical site is effectively discharged, so that the medical aspirator may contribute to shortening of a recovery period of a patient.

A device and method for aspirating bone barrow. The device includes a double syringe assembly having a distal syringe and a proximal syringe coupled to the distal syringe. A plunger includes a distal end disposed within a barrel of the distal syringe and a proximal end disposed within a barrel of the proximal syringe. A needle assembly is coupled to the double syringe assembly and includes a needle having an outer tube and an inner tube disposed within the outer tube. Upon actuation of the plunger, the distal syringe aspirates bone marrow through the outer tube of the needle and into a chamber of the distal syringe. At the same time, the proximal syringe injects fluid through the inner tube of the needle at the same rate in which the bone marrow is aspirated.

An embodiment of the invention is directed to a bone marrow aspiration device comprising a plurality of syringes, each of which operates in a series of sequential steps to obtain bone marrow of high quality and therapeutic value, i.e., having a high mesenchymal stem cell (MSC) MSC/ml number. In certain embodiments, a syringe may be used along with a collection vessel or with a second syringe. A further embodiment of the invention is directed to a method for using the bone marrow aspiration device as set forth herein.

The tissue therapy device includes a sealant layer and a suction apparatus. The sealant layer creates a sealed enclosure between it and the surface of a patient by forming an airtight seal around an area of tissue. The suction apparatus is in fluid communication with the sealant layer and together, create a closed, reduced pressure therapy system. The suction apparatus self-creates reduced pressure by decreasing the density of air molecules underneath the sealant layer by expanding the volume of the air molecules.

The present invention provides actuation mechanisms that incorporate a transmission assembly that allows the mechanisms to cause actuation of workpieces according to a plurality of transmission modes (e.g., at least one forward transmission mode and at least one reverse transmission mode) on demand. Motion, direction, and/or force can be controlled by selecting the corresponding transmission mode. The mechanisms preferably are trigger-actuated by hand (i.e., manually) to cause movement of a workpiece in a desired direction. Desired directions can be linear or nonlinear. The same hand used for trigger action can also be used to change transmission modes in many modes of practice, even while using substantially the same grip used for trigger actuation. In other instances, actuation can be automated rather than manual. Preferably, both actuation and witching among transmission modes can be accomplished with one hand, even while maintaining substantially the same grip that is used for actuation.

A vacuum overdressing sealing a wound. The dressing has a layer of overdressing that is generally rectangular with a top side and a bottom side and two longer ends and two shorter ends. The overdressing layer has a port through which a vacuum can be pulled when the wound is sealed by the dressing. The port is located near one of the ends of the dressing.

Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, positioning a distal portion of a catheter proximate to the clot material within the blood vessel. The method can further include coupling a pressure source to the catheter via a tubing subsystem including a valve or other fluid control device and, while the valve is closed, activating the pressure source to charge a vacuum. The valve can then be opened to apply the vacuum to the catheter to thereby aspirate at least a portion of the clot material from the blood vessel and into the catheter.

Described herein are alarm systems for suction devices for reduced pressure therapy. Alarms systems provide alerts to the patient and/or practitioner regarding the ability of the suction device to continue to provide negative pressure to a tissue region. Alarm systems comprise a sensor mechanism, which is capable of detecting the position of a slidable seal within the suction device, and generating an alert. Certain variations of alarms systems comprise magnetic field sensitive switches and/or electric switches. Other variations of alarm systems comprise rotary encoders to detect the motion and location of constant force springs, which signal the notification mechanism to issue alerts accordingly. Described herein are alarm devices configured to retain a suction device therein and to attach the suction device to a patient. The alarm devices disclosed herein detect the depleted state of the suction device and are capable of retaining the suction device in a plurality of orientations.