An automatic fluid injection device comprising: a base body (1) for coming into contact with an injection zone; a support assembly (2) for supporting an actuator mechanism (5, 6, 7) that is controlled by power supply means (11); at least one fluid reservoir (3), each containing an injection piston (35), arranged in said base body (1); a needle assembly (100) comprising an insertion actuator (8), needle movement means (9, 9′), a priming needle (101) for associating with each reservoir (3) and for penetrating into said reservoir (3) before moving its piston (35), and an injection needle (102) for penetrating into the injection zone and for injecting the contents of said reservoir(s) (3) into said injection zone, said device including at least one actuator button (200) for priming, inserting the injection needle into the injection zone, administering fluid, and then retracting the injection needle.

A system is disclosed. The system includes a reservoir for containing a fluidic medium, the reservoir including a front surface, a resilient cylindrical flexure portion connected to the front surface, the resilient cylindrical flexure portion comprising an accordion-like structure that is able to expand and contract to change an interior volume within the resilient cylindrical flexure portion, a central passageway within the resilient cylindrical flexure, and a collection chamber connected to the central passageway. Also, a system including a reservoir, a plunger head located within the reservoir, a plunger arm connected to the plunger head, a driving shaft connected to the plunger arm, and a motor connected to the driving shaft, the motor controllable to move the drive shaft in a first motion and a second motion so as to move the advance plunger head and retract the plunger head within the reservoir.

A priming system including a resilient chamber having flexible walls and a first check valve in a first fluid pathway between the resilient chamber and a fluid reservoir such that a fluid flows through the first check valve only in a direction from the fluid reservoir toward the resilient chamber and the fluid returns to the fluid reservoir through a second fluid pathway between the resilient chamber and the fluid reservoir upon compression of the walls of the resilient chamber.

A cassette for attachment and use with an infusion pump apparatus. The cassette head having a low profile cassette head for attaching to the infusion pump apparatus and a flexible reservoir attached to the cassette head that can be filled with a fluid to be administered to a patient. The reservoir is enclosed in a flexible cover attached to the cassette. The flexibility of the cover and the reservoir inhibits the cassette head from disengaging from the infusion pump apparatus and allows the infusion pump apparatus to be primed by squeezing or pressing the cover and reservoir.

A drive mechanism (100) for use with a drug container (50) in a drug pump, the drug container (50) having a barrel (58) and a plunger seal (60), including a tether, an electrical actuator (101) and a gear interface. Rotation of the gear interface is controlled by the actuator (101). A gear assembly rotationally engages with the gear interface. The gear assembly includes a main gear and a regulating mechanism. Release of the tether is metered by the gear assembly through the regulating mechanism. A piston (110, 1110, 2110) is connected to the tether and is disposed in the barrel (58) and configured to translate axially within the container. A biasing member is disposed at least partially within the barrel (58) and is retained in an energized state between the piston (110, 1110, 2110) and drive housing, wherein the release of the tether controls the free expansion of the biasing member from its energized state and the axial translation of the piston (110, 1110, 2110).

An infusion set (1) includes a first flow channel (10) constituted by a pliable tube (10a) and including a spike (11) provided at one end thereof, a second flow channel (20) constituted by a pliable tube (20a) and including a lock connector (50) provided at one end thereof, the lock connector (50) including a lock mechanism (60) that is brought into engagement with a female connector (200), a third flow channel (30) constituted by pliable tubes (30a, 30b and 30c) and including a male connector (31) provided at one end thereof, and a three-way stopcock (40) to which another end of the first flow channel, another end of the second flow channel and another end of the third flow channel are connected. The three-way stopcock includes a handle (41) that can be switched between a first position that brings the first flow channel and the third flow channel into communication with each other and a second position that brings the second flow channel and the third flow channel into communication with each other.

A method for the re-anticoagulation of platelet rich plasma in a blood apheresis system includes priming the blood apheresis system with anticoagulant, such that a volume of anticoagulant is transferred to a PRP container. The method may then transfer the anticoagulant within the PRP container to a red blood cell container, and collect a volume of platelet rich plasma within the PRP container. The platelet rich plasma may be collected in a plurality of cycles. Between collection cycles, the method may transfer a portion of the volume of anticoagulant from the red blood cell container to the PRP container.

An injector head with rotation mechanism allows selection between a state in which a syringe assumes a priming orientation with a through hole of the syringe positioned upper than the injector head body, and a state in which the syringe assumes a contrast agent injectable orientation with the through hole of the syringe positioned lower than the injector head body.

Delivery systems and methods for forming and delivering biomaterials from two components are described herein. In particular, apparatus and methods for performing controlled delivery of multicomponent delivery of biomaterials into or onto a body part, such as a body lumen are described. More specifically, in some embodiments, the apparatus and methods are directed towards controlled delivery of micro-volumes of biomaterials into or onto a target location, the micro-volumes being defined as 0.001 mL-1 mL (or 1 μL-1,000 μL) of volume.

A cassette for operatively connecting administration set tubing to an infusion pump includes a thumb tab having a thumb surface, and a tubing connector having an in-line occluder spaced laterally from the thumb tab. The cassette is configured such that a user's hand will cradle the cassette by pressing a thumb of the user's hand against the thumb surface and wrapping at least one finger of the user's hand around and under the thumb tab, whereby a user may apply pressure to tubing connected to the tubing connector at a location corresponding to the in-line occluder in a direction generally opposite to a direction in which the thumb is pressed against the thumb surface, thereby bypassing the in-line occluder and allowing flow through the tubing.