An implantable system for delivering fluids, such as drugs, to one or more anatomical structures in a patient's (i.e., human or animal) body. A number of medical conditions require continual and/or periodic administration of fluids (e.g., drugs) to target regions (e.g., anatomic organs) of the body. Accessibility to those target regions might be limited technically for ex. and not limited to: frequent endoscopic, radiologically guided or surgical approaches. The system delivers the fluid needed in a continual or intermittent fashion to the target region. It controls the amount of fluid delivered to the target region and measures the intended physiologic effect of the fluid delivered.

In some embodiments, a device may include an intraventricular access device and an infusion device. The intraventricular access device may include more than one catheter and a container. In some embodiments, the catheter may include an aspiration lumen and an infusion lumen. A distal end of the intraventricular portion of the catheter may be positionable, during use, in a subject's brain fluid. In some embodiments, the container may be coupled to a proximal end of the aspiration lumen. The proximal end of the aspiration lumen may be in fluid communication with the container. The proximal end of the infusion lumen may be in communication with an infusion pump. In some embodiments, the device inhibits cross contamination between a first fluid in the aspiration lumen and a second fluid in the infusion lumen. In some embodiments, the container may include a barrier positioned between a proximal opening of the aspiration lumen and at least a portion of the infusion lumen adjacent to and/or associated with the container. The barrier may inhibit penetration of a surgical instrument.

A fluid injector system and method for preventing pressurized backflow of a second fluid into a first reservoir containing a fluid is described. The fluid injector system includes a control device programmed or configured to actuate a second drive component to pressurize and inject the second fluid through the fluid conduit, and while the second drive component is actuated, actuate a first drive component to introduce intermittent pulses of the first fluid to create a flow front interface between the first fluid and the second fluid in the fluid conduit to prevent backflow of the second fluid through the fluid conduit into the first fluid reservoir.

An infusion pump (100) includes a plunger (110) configured to squeeze a section of an infusion tube (150). A proximal valve (120), proximal to the plunger, ascends to allow infusion fluid intake from a reservoir to the infusion tube and descends to inhibit infusion fluid intake from the reservoir to the infusion tube. A distal valve (125), distal to the plunger, ascends to allow infusion fluid flow past the distal valve, and descends to inhibit infusion fluid flow past the distal valve. A controller (141) controls the plunger, proximal valve, and distal valve by initiating descending of the plunger concurrently with or prior to the ascending of the distal valve, such that the descending of the plunger compensates for suction produced by the ascending of the distal valve, thereby reducing backflow of fluid from the subject. Other applications are also described.

Systems and methods are provided for intermittent microinfusion. A system may include a pump and an IV set that includes a y-port valve disposed below a pump interface portion of the IV tubing. The y-port valve may include an internal valve member that allows fluid to flow from the pump to a patient when no syringe is attached to the y-port. The internal valve member may be moved by the attachment of a syringe containing the medication to be infused to the y-port such that the fluid pathway from the pump to the patient is blocked and fluid from the syringe can be injected into the IV tubing between the y-port valve and the pump. The pump may retrograde pump the medication into the tubing via the y-port valve and then forward pump the medication to the patient when the syringe is removed from the y-port.

A flow control device includes a housing including a primary inlet and a secondary inlet each disposed on an upper surface of the housing, and an outlet disposed on a lower surface of the housing gravitationally downstream of the primary and secondary inlets. A chamber is disposed within the housing and fluidly connects the primary and secondary inlets with the outlet. A valve member is pivotally mounted on an upper surface of the chamber, the valve member configured to pivot in response to higher fluid pressure from gravitational fluid flow through one of the primary inlet and the secondary inlet.

A stepped catheter comprising a distal portion of smaller diameter than a proximal portion, wherein the distal portion defines a flow aperture configured to deliver fluid passing through the catheter from the proximal portion to the flow aperture. The catheter may include a flow restrictor located within a lumen of the catheter at or near the flow aperture. A filter element may also be included and located within the lumen of the catheter at a location upstream of the flow restrictor.

A fluid injector system and computer program product on a control device of the fluid injector system is described. The control device has at least one processor programmed or configured to actuate a second drive component to pressurize and inject the second fluid through the fluid conduit, and while the second drive component is actuated, actuate a first drive component to introduce intermittent pulses of the first fluid to create a flow front interface between the first fluid and the second fluid in the fluid conduit to prevent backflow of the second fluid through the fluid conduit into the first fluid reservoir.

In some embodiments, a device may include an intraventricular access device and an infusion device. The intraventricular access device may include more than one catheter and a container. In some embodiments, the catheter may include an aspiration lumen and an infusion lumen. A distal end of the intraventricular portion of the catheter may be positionable, during use, in a subject's brain fluid. In some embodiments, the container may be coupled to a proximal end of the aspiration lumen. The proximal end of the aspiration lumen may be in fluid communication with the container. The proximal end of the infusion lumen may be in communication with an infusion pump. In some embodiments, the device inhibits cross contamination between a first fluid in the aspiration lumen and a second fluid in the infusion lumen. In some embodiments, the container may include a barrier positioned between a proximal opening of the aspiration lumen and at least a portion of the infusion lumen adjacent to and/or associated with the container. The barrier may inhibit penetration of a surgical instrument.

The present invention relates to an extensible drug injection device capable of injecting a drug from a location away from a patient, and an operation method therefor. Disclosed is a drug injection device comprising: a first sub-line of which one end joins with a main line, connected from a first drug storage part for storing a first drug to be injected into a patient to the body of the patient such that the first drug flows therein, and of which the other end is extended to the other side; a second drug injection part which is connected to the first sub-line and which injects a second drug that is different from the first drug; and a second drug pumping part which is connected to the first sub-line, and which pushes, to the main line, the second drug having been injected by the second drug injection part into the first sub-line.