Methods and systems for selection of dosimetry levels and sphere amounts of radioactive compounds for use in a radioembolization procedure for procedure planning may include inputting activity parameter information into a dosimetry portal of a dosimetry selection tool; determining a customized activity based on the activity parameter information and one or more customized activity algorithms; generating one or more sphere amount and dosage recommendations based on the customized activity and one or more dosimetry selection algorithms; selecting one of the one or more sphere amount and dosage recommendations as a selected sphere amount and dosage recommendation; and generating a radioactive compound order for the radioembolization procedure based on the customized activity and the selected sphere amount and dosage recommendation.

In one aspect, a combinatorial drug delivery device is provided for delivering a predetermined selection of drug components. The device includes a plurality of modules, each including: a body having an interior volume; a spike plate movably disposed in the interior volume, the spike plate having a protruding cannula and first and second ports. The device also includes a base tray which includes: a framework defining a plurality of wells, each of the wells formed to insertingly receive one of the modules; for each of the wells, first and second inlet ports formed to interface with the first and second ports of the module being received in the respective well; passageways to connect certain wells with adjacent wells to permit fluid flow therebetween. For each of the wells, the spike plate of the respective module being maintained in a stationary position with the module being inserted into the well.

A medical fluid control device with a fluid flow housing has at least one attachment port for attaching and removing an external medical fluid-guiding component and at least one connection port for connecting to a further functional component of the medical fluid conduction system, and with an adjustment member for controlling a flow of fluid relative to the at least one attachment port and/or the at least one connection port. A particulate filter with a pore width of between 2 μm and 15 μm is integrated in the attachment port.

A container holder for an injector for injecting a fluid into the human or animal body includes at least one container clamping member for clamping onto a container that is filled with the fluid and a temperature control device for bringing the temperature of the container to a predefined temperature. To be able to clamp containers of different shapes and sizes onto the container holder and to bring the temperature of the containers to a desired temperature without any thermal loss, by means of the temperature control device, and to ensure easy and unimpeded clamping and removal of the container, the temperature control device is connected to a transporting device, by means of which the temperature control device can be brought into and out of thermal contact with the container that is clamped onto the container clamping member.

Methods and systems for determination of flow parameters of administered fluid from a radioembolization delivery device may include translationally moving a device delivery arm of the radioembolization delivery device in a translational direction, wherein the device delivery arm is coupled to a syringe holder such that move in the translational direction one of proximally or distally advances the syringe holder; sensing, via one or more pattern sensors, a corresponding movement of a pattern associated with the translational device delivery arm movement as a sensed pattern movement; generating, via the one or more pattern sensors, one or more output signals based on the sensed pattern movement; and generating, via a processor, a flow rate of the administered fluid, a flow amount of the administered fluid, and/or the translational direction of movement of the device delivery arm with respect to the syringe holder based on the one or more

A valve and a method for administering a plurality of drug fluids to a patient are disclosed. For each drug fluid, the valve may be rotated into a selected drug position associated with the drug fluid. With the valve being in the selected drug position, a backpriming may be performed of a connector line of a drug container containing the drug fluid. Thereafter, the drug fluid may be administered with the valve being in the same selected drug position. Thereafter, the valve may be flushed, optionally while maintaining the same selected valve position.

A liquid medicine injection apparatus capable of injecting an additional fluid after completion of injection of a liquid medicine is provided. The apparatus includes a cylinder elongated in a direction and having a nozzle formed at one end of the cylinder; a piston installed to be hermetically movable within the cylinder in the direction; an injector provided at the other end of the cylinder to allow the piston to be moved; a fluid tank for storing a fluid in a sealed state; a needle unit disposed between the nozzle and the fluid tank; and a cap member provided between the needle unit and the fluid tank and deformable to allow the needle unit to penetrate the fluid tank.

A system for the delivery of therapeutic substances to cavities of a patient. The system can include a handpiece tool coupled with a pump. The handpiece tool can include a shaft including a first portion of a channel coupled to a multi-input tubing. The handpiece tool can include an angled portion coupled with the shaft. The handpiece tool can include a second portion of the channel, wherein the angled portion positions a tip portion within a cavity, wherein the tip portion projects from the angled portion and includes an outlet and a third portion of the channel. The handpiece tool can include a collar a distance from the outlet, the collar configured to control a distance the tip portion projects. The handpiece tool can include a mixing chamber configured to receive the components of the drug and output the mixed drug via the third portion of the channel.

A delivery system configured to be secured on a patient skin which comprises a first container having a first variable volume; a second container having a second variable volume; and a skin adherable unit configured to secure the first container and the second container to the patient skin. The medical device may further comprise a containers' interface configured to operatively couple the first container and the second container such that a volume increase of the second variable volume may induce a volume decrease of the first variable volume. Preferentially, the system further comprises a vent device configured to prevent any unintended pressure increase in the first storage compartment.

In the present disclosure, embodiments of dual-stage syringes are disclosed along with delivery systems incorporating the dual-stage syringes. Embodiments of the dual-stage syringes described herein include sleeved dual-stage syringes, turn-key dual-stage syringes and dual-stage syringes including one or more one-way valves.