An orientation independent delivery device. The delivery device includes a gas chamber, a delivery chamber, a gas cell, and a delivery aperture. The gas chamber includes a gas-side rigid portion and a gas-side flexible barrier. The gas-side flexible barrier is sealed to the gas-side rigid portion. The delivery chamber includes a delivery-side rigid portion and a delivery-side flexible barrier. The delivery-side flexible barrier is sealed to the delivery-side rigid portion and is oriented adjacent to the gas-side flexible barrier. The gas cell is coupled to the gas-side rigid portion of the gas chamber. The gas cell increases a gas pressure within the gas chamber to expand the gas-side flexible barrier. Expansion of the gas-side flexible barrier applies a compressive force to the delivery-side flexible barrier allowing a delivery material to escape from the delivery chamber.

A fluid delivery device comprises a fluid reservoir for containing medicament. The fluid reservoir is sealed proximate one end with a sliding seal piston. A delivery path is configured to fluidly couple the fluid reservoir and a patient wearing the fluid delivery device. A basal engine mechanism is configured to directly or indirectly move the sliding seal piston in the fluid reservoir at a controlled basal rate. A bolus mechanism configured to move the basal engine relative to the fluid reservoir and directly or indirectly move the sliding seal piston in the fluid reservoir a discrete bolus amount at a time.

A fluid pumping system may include an electroosmotic pump; and a separation member provided at least one end of the electroosmotic pump, and configured to separate the fluid and a transfer target fluid. The electroosmotic pump may include: a membrane that allows a fluid to move therethrough; and a first electrode and a second electrode which are respectively provided at two opposite sides of the membrane, and each of which is formed of a porous material or has a porous structure to allow a fluid to move therethrough; each of the first electrode and the second electrode may be made of porous carbon only; and an electrochemical reaction of the first electrode and the second electrode may take place as a cation is moved in a direction whereby a charge balance is established.

Chemical engines and processes for their use and construction are described. The chemical engines can provide powerful and compact devices, especially autoinjectors for the rapid, powered injection of viscous medicines. Novel formulations and designs of chemical engines and delivery technologies employing the chemical engines are described.

A fluid pumping system may include an electroosmotic pump; and a separation member provided at least one end of the electroosmotic pump, and configured to separate the fluid and a transfer target fluid. The electroosmotic pump may include: a membrane that allows a fluid to move therethrough; and a first electrode and a second electrode which are respectively provided at two opposite sides of the membrane, and each of which is formed of a porous material or has a porous structure to allow a fluid to move therethrough; each of the first electrode and the second electrode may contain a conductive polymer in which an anionic polymer is included or may be made of porous carbon only; and an electrochemical reaction of the first electrode and the second electrode may take place as a cation is moved in a direction whereby a charge balance is established.

Devices and methods are provided for drug delivery. The device may include a housing configured for intraluminal deployment into a human or animal subject and first and second reservoirs within the housing, each reservoir having an actuation end, an opposed release end, and a plug moveable from the actuation end toward the release end. First and second drug formulations may be contained in the first and second reservoirs, respectively. The device may also include one or more actuation systems configured to drive the first and second plugs so as to drive the first and second drug formulations from the first and second reservoirs. The housing may include a porous membrane sidewall in fluid communication with the release ends of the first and second reservoirs, the porous membrane sidewall being configured to distribute the first and second drug formulations driven from the first and second reservoirs.

An orientation independent delivery device. The delivery device includes a gas chamber, a delivery chamber, a gas cell, and a delivery aperture. The gas chamber includes a gas-side rigid portion and a gas-side flexible barrier. The gas-side flexible barrier is sealed to the gas-side rigid portion. The delivery chamber includes a delivery-side rigid portion and a delivery-side flexible barrier. The delivery-side flexible barrier is sealed to the delivery-side rigid portion and is oriented adjacent to the gas-side flexible barrier. The gas cell is coupled to the gas-side rigid portion of the gas chamber. The gas cell increases a gas pressure within the gas chamber to expand the gas-side flexible barrier. Expansion of the gas-side flexible barrier applies a compressive force to the delivery-side flexible barrier allowing a delivery material to escape from the delivery chamber.

Provided is a system for dispensing fluid. The system includes a housing defining a chamber; an inflatable bag disposed in the chamber and adapted to contain a fluid, the bag being in fluid communication with a flow path for flow of the fluid out of the bag; and a pressure source for inflating the bag to force the fluid from the bag to the flow path at a controlled rate. The bag inflates against an inner surface of the housing such that, prior to the bag being fully inflated, the fluid contained in the bag is forced from the bag at the controlled rate.

A system and method is disclosed for detecting remaining battery voltage or capacity in an infusion device and generating alarms based on the detection. The battery lifetime extension method includes providing an infusion device that derives its power from a rechargeable battery. The infusion device may derive its power from a rechargeable battery. Furthermore, the infusion device receives, at predetermined intervals of time in real-time sensor data comprising: a voltage, a change in the voltage over the predetermined interval of time, an average current, a temperature, and a remaining voltage or capacity reported by a battery gas gauge integrated circuit (“IC”) associated with the rechargeable battery. An improved and customized neural network model utilizes the sensor data to determine an indicia of the actual remaining voltage or capacity of the rechargeable battery in real-time. The indicia may be used to lengthen and/or abate ongoing medical infusion therapy.

Systems and methods for delivering a medication to a person experiencing an emergency medical event without requiring intervention or action on the part of the person. A device encases a reservoir of medication and a delivery mechanism. Sensors in the housing sense a physical attribute of the person and circuitry monitors information collected by the sensors to determine if the person is experiencing a severe medical condition or event based on the information. An input device on or in the housing, such as a button, may be used or activated by the person if the detected condition or event is a false positive to cancel further action. If the system does not include the button or if the user does not press it in time, the system activates the delivery device and injects the medication into the person.