A liquid medicine injection apparatus capable of injecting an additional fluid after completion of injection of a liquid medicine is provided. The apparatus includes a cylinder elongated in a direction and having a nozzle formed at one end of the cylinder; a piston installed to be hermetically movable within the cylinder in the direction; an injector provided at the other end of the cylinder to allow the piston to be moved; a fluid tank for storing a fluid in a sealed state; a needle unit disposed between the nozzle and the fluid tank; and a cap member provided between the needle unit and the fluid tank and deformable to allow the needle unit to penetrate the fluid tank.

A liquid medicine injection apparatus of the present invention is directed to improvement of a precise and detailed technology that can implement two functions of a high liquid medicine injection pressure and easy filling of the apparatus with a liquid medicine in a single apparatus without a separate additional unit, i.e., a technology for effectively adjusting an internal pressure of the apparatus depending on a liquid medicine filling mode and a liquid medicine injection mode. In the liquid medicine injection apparatus of the present invention, when an internal pressure of the apparatus exceeds a preset pressure due to a gas generated in a gas-generating unit of the apparatus, a switch member in the liquid medicine injection apparatus can operate as a pressure regulating valve, thereby constantly keeping the internal pressure of the apparatus at the preset pressure.

The present invention provides a delivery device which comprises a substrate, a rigid shell a diaphragm, a cannula, an electrode and an electronic device chamber. The substrate has a first side and a second side. The second side is opposite to the first side. The rigid shell is disposed on the first side of the substrate. A chamber is defined by the rigid shell and the substrate. The diaphragm is configured within the chamber to divide the chamber into an upper reservoir and a lower reservoir. The cannula penetrating through the rigid shell and in fluid communication with the upper reservoir. The electrode is disposed on the first side of the substrate. The electronic device chamber is electrically connecting to the electrode.

A device is disclosed. The device includes a housing that defines a chamber. The chamber is to be at least partially filled with an electrolyte material. The device also includes a plurality of electrodes that are at least partially embedded in the housing and exposed to the chamber. The device further includes an access port that provides fluid communication between an interior of the housing and the outside environs.

A displacement-generating battery cell for driving a drug-delivery device is described. The cell may include at least one volume-changing element. The cell may include a housing formed according to a concertina-shaped design with folds in the walls thereof and may contain an internal chemical reaction system. The chemical reaction system may include an electrode. The electrode may be the volume-changing element. The arrangement of said chemical reaction system may be such that an expansion of the volume-changing element in a direction lengthens the cell and thus reduces the extent of the folds. Drug-delivery devices including the displacement-generating battery cell are also described.

The present application provides a self-powered drug-delivery device. The device includes a chamber having a wall. The chamber contains a fluid and is in connection with an administration means. The device also includes a displacement-generating battery cell. The device further includes an electrically-controlled battery unit, which includes the displacement-generating battery cell coupled to the chamber by a coupling means. The displacement-generating battery cell includes an element that changes shape as a result of charge or discharge of the battery cell so as to cause a displacement within the battery unit. The arrangement of the battery unit, the coupling means, the wall, the chamber, and the administration means is such that the displacement derived from the battery unit is conveyed by the coupling means to cause displacement of the wall of the chamber such that the fluid is expelled from the chamber to force a drug towards the administration means.

A fluid delivery device comprises a fluid reservoir for containing medicament. The fluid reservoir is sealed proximate one end with a sliding seal piston. A delivery path is configured to fluidly couple the fluid reservoir and a patient wearing the fluid delivery device. A basal engine mechanism is configured to directly or indirectly move the sliding seal piston in the fluid reservoir at a controlled basal rate. A bolus mechanism configured to move the basal engine relative to the fluid reservoir and directly or indirectly move the sliding seal piston in the fluid reservoir a discrete bolus amount at a time.

Self-regulating electrolytic gas generator and implant system including the same. In one embodiment, the electrolytic gas generator is a water electrolyzer and includes a polymer electrolyte membrane with an anode on one side and a cathode on the other side. Anode and cathode seals surround the peripheries of the anode and cathode and include inlets for water and outlets for oxygen and hydrogen, respectively. A cathode current collector is placed in contact with the cathode, and an anode current collector, which may be an elastic, electrically-conductive diaphragm, is positioned proximate to the anode. The anode current collector is reversibly deformable between a first state in which it is in direct physical and electrical contact with the anode and a second state in which it distends, due to gas pressure generated at the anode, so that it is not in physical or electrical contact with the anode, causing electrolysis to cease.

A flushing apparatus according to embodiments of the present disclosure includes: a main body configured to connect a connection pipe for guiding a hazardous medicinal liquid harmful to a human body when exposed to an ambient air and a patient connection module for injecting the hazardous medicinal liquid into a patient, the main body configured to form a first flow path for guiding the hazardous medicinal liquid from the connection pipe to the patient connection module, the main body including a flushing portion forming a second flow path connected to a predetermined connection point located between both ends of the first flow path; and a flow rate reduction part disposed at upstream side of the connection point in the first flow path and configured to reduce a flow rate of the hazardous medicinal liquid flowing through the first flow path. The present disclosure shows various embodiments of the flushing apparatus.

A fluid delivery device comprises a fluid reservoir for containing medicament. The fluid reservoir is sealed proximate one end with a sliding seal piston. A delivery path is configured to fluidly couple the fluid reservoir and a patient wearing the fluid delivery device. A basal engine mechanism is configured to directly or indirectly move the sliding seal piston in the fluid reservoir at a controlled basal rate. A bolus mechanism configured to move the basal engine relative to the fluid reservoir and directly or indirectly move the sliding seal piston in the fluid reservoir a discrete bolus amount at a time.