A drug delivery device (1) comprising a delivery unit (2) receiving a drug cartridge (3) containing a drug to be administered to a patient in need thereof, the delivery unit comprising a subcutaneous delivery mechanism (7) including a needle (24), a needle support (8) to which the needle is mounted, and a needle actuation mechanism (9) configured to move the needle from a retracted position within a housing (5) of the delivery unit (2), to an extended delivery position where the needle projects through a base wall (14) of the housing. The needle actuation mechanism comprises a rotary actuator (10) configured to engage an engagement lever (11) coupled to the needle support (8) for translating the needle support between retracted and extended delivery positions.

An infusion system for infusing a medication in a patient, comprising a medication dose dispensing device and a control device for controlling the dispensing device. The infusion system can be configured in a non-operating configuration, in which the dispensing device and the control device are spaced apart from each other, and in an operating configuration, in which the dispensing device and the control device are temporarily proximity-coupled. The actuating rotor of the control device and the actuated rotor of the dispensing device have a common rotation axes, and the system can compensate or block the rotation of the control device with respect to the dispensing device.

Intrathecal drug delivery pumps can aspirate cerebrospinal fluid (CSF) when the drug reservoir is empty or at other times to maintain a continuous or cyclic fluid flow through the pump and the delivery catheter. This addresses the potential need for continuous infusion to maintain an un-occluded fluid pathway to the intrathecal space by providing an “active port” that aspirates and expels CSF to keep fluid flow going without infusing a drug or requiring saline to fill the pump. If drug refill visits are missed, CSF could be used to keep the pump mechanism functional rather than having it run dry requiring replacement or requiring saline injections to keep the pump mechanism functioning. In addition, by having the pump aspirate CSF into the body of the pump, it would be possible to monitor biomarkers using systems in the fluid pathway and pressure differences for possible issues related to CSF management.

In some examples, a medical system includes a catheter having a proximal end and a distal end, a suction source configured to apply a suction force to the catheter to aspirate a material proximate the distal end of the catheter and from within vasculature of the patient, and a fluid controller configured to control an introduction of a fluid into the catheter between the proximal and distal ends to reduce an amount of blood aspirated from a blood vessel of the vasculature of the patient through the catheter.

An apparatus for determining the volume of fluid dispensed. The apparatus has an acoustic volume sensor that acoustically excites a reference volume and a measurement chamber with a loudspeaker and measures the acoustic response with microphones acoustically coupled to the reference and the measurement chamber. The loudspeaker and sensing microphones are connected to the measurement chamber by separate ports. A detachable dispensing chamber is coupled to the acoustic volume sensor. The volume of the fluid dispensed is determined by a processor based on the acoustic response of the microphones to acoustic excitement by the loudspeaker.

Fill stations and base stations are provided for personal pump systems. The fill stations may be opened and closed to accept a reservoir and to allow fluid to be introduced into the reservoir for use with personal pump systems. The fill stations may hold the reservoir at a tilt relative to an underlying surface and may discourage overfilling of the reservoir. The filling stations may also include viewing windows having fluid lines marked thereon for indicating volume of fluid within the reservoir.

An apparatus for determining the volume of fluid dispensed. The apparatus has an acoustic volume sensor that acoustically excites a reference volume and a measurement chamber with a loudspeaker and measures the acoustic response with microphones acoustically coupled to the reference and the measurement chamber. The loudspeaker and sensing microphones are connected to the measurement chamber by separate ports. A detachable dispensing chamber is coupled to the acoustic volume sensor. The volume of the fluid dispensed is determined by a processor based on the acoustic response of the microphones to acoustic excitement by the loudspeaker.

A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.

A method and system is disclosed for operating a medical device with or without a cassette in place. A method is disclosed for adding additional VTBI to an ongoing infusion without stopping the infusion and with maintaining the infusion parameters. A method and system is disclosed for changing the CCA without having to interrupt or completely stop an ongoing infusion. Quick titration buttons are provided to allow improved navigation between various delivery display screens.

A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.