Infusion systems, infusion devices, and related operating methods are provided. An exemplary method involves operating an infusion device to deliver fluid to a user in accordance with a first operating mode of a plurality of operating modes, obtaining operational information pertaining to the first operating mode, and obtaining clinical information pertaining to the user. A destination operating mode of the plurality of operating modes is determined based at least in part on the operational information and the clinical information, and the infusion device is operated to deliver the fluid in accordance with the destination operating mode in a manner that is influenced by at least a portion of the operational information pertaining to the first operating mode.

Certain embodiments provide multi-medicament or single medicament infusion systems for preventing the cross-channeling or improper delivery of medicaments. The system may include one or more of an infusion pump, medicament cartridges, cartridge connectors, a multi-channel fluid conduit, and an infusion set. The medicament cartridges may be sized and shaped differently such that the medicament reservoirs can only be inserted into the pump under selected configurations.

Medical devices, systems, and methods related thereto a glucose monitoring system having a first display unit in data communication with a skin-mounted assembly, the skin-mounted assembly including an in vivo sensor and a transmitter. The first display unit and a second display unit are in data communication with a data management system. The first display unit comprises memory that grants a first user first access level rights and the second display unit comprises memory that grants a second individual second access level rights.

An example system for therapy delivery includes one or more processors configured to in response to a prediction indicating that the meal event is to occur, output instructions to an insulin delivery device to deliver a partial therapy dosage, to a device to notify the patient to use the insulin delivery device to take the partial therapy dosage, or to the insulin delivery device to prepare the partial therapy dosage prior to the meal event occurring, and in response to a determination indicating that the meal event is occurring (e.g., based on movement characteristics of a patient arm), output instructions to the insulin delivery device to deliver a remaining therapy dosage, to the device to notify the patient to use the insulin delivery device to take the remaining therapy dosage, or to the insulin delivery device to prepare the remaining therapy dosage.

A processor-implemented method comprises obtaining current operational context information associated with a sensing device; obtaining an expected calibration factor parameter model associated with a patient; calculating an expected calibration factor value based on the expected calibration factor parameter model and the current operational context information; obtaining one or more electrical signals from the sensing device, the one or more electrical signals having a signal characteristic indicative of a physiological condition; converting the one or more electrical signals into a calibrated measurement value for the physiological condition using the expected calibration factor value; and outputting the calibrated measurement value for the physiological condition.

Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

A sensor system capable of detecting tissue counter pressure from patients that utilize infusion pumps to administer their medication is provided. Embodiments include a retrofitted piece that is placed between the user's infusion set and pump, as well as a “smart” infusion set configured for measuring characteristics of a fluid traveling therethrough. Hardware is provided that couples with the sensor to store, analyze, and compare data to distinguish between normal and non-normal injection/infusion profiles. An alert system notifies the user of a malfunction within the pump, within the infusion set, or at the injection/infusion site.

Techniques disclosed herein relate generally to notification generation in a medical device system. In some embodiments, the techniques involve generating a first notification via a medical application executing on a first device, determining that the first notification was not acknowledged within a predetermined time frame, and causing generation of a second notification at a medical device carried by a user to notify the user that the first notification has not been acknowledged.

A novel embodiment of a pump mechanism, for example, of the type that would be used in a wearable drug delivery system, comprises, in a preferred embodiment, a reservoir, a plunger, disposed within the reservoir and driven by a coiled flexible linkage connected to a drive mechanism, such that a force imparted by the drive mechanism causes the coiled flexible linkage to uncoil, causing a linear translation of the plunger through the reservoir to force a liquid drug contained within the reservoir through a fluid port to a patient.

A medical fluid pump, such as a syringe pump or infusion pump, includes a housing, a front flap hinged to a front side of the housing, and a carrying handle pivotally connected to opposite first and second side surfaces. The carrying handle is pivotable from a storage position to a carrying position in which the carrying handle is disposed above the housing. A plurality of electrical and mechanical components, which are contained within the housing, are necessary for all of the intended functions of the medical fluid pump. A selection of components from the electrical and mechanical components are provided as tare elements, placed within the housing such that a center of gravity of the medical fluid pump is substantially below the carrying handle in the carrying position.