The present application provides a self-powered drug-delivery device. The device includes a chamber having a wall. The chamber contains a fluid and is in connection with an administration means. The device also includes a displacement-generating battery cell. The device further includes an electrically-controlled battery unit, which includes the displacement-generating battery cell coupled to the chamber by a coupling means. The displacement-generating battery cell includes an element that changes shape as a result of charge or discharge of the battery cell so as to cause a displacement within the battery unit. The arrangement of the battery unit, the coupling means, the wall, the chamber, and the administration means is such that the displacement derived from the battery unit is conveyed by the coupling means to cause displacement of the wall of the chamber such that the fluid is expelled from the chamber to force a drug towards the administration means.

The present application provides a self-powered drug-delivery device. The device includes a chamber having a wall. The chamber contains a fluid and is in connection with an administration means. The device also includes a displacement-generating battery cell. The device further includes an electrically-controlled battery unit, which includes the displacement-generating battery cell coupled to the chamber by a coupling means. The displacement-generating battery cell includes an element that changes shape as a result of charge or discharge of the battery cell so as to cause a displacement within the battery unit. The arrangement of the battery unit, the coupling means, the wall, the chamber, and the administration means is such that the displacement derived from the battery unit is conveyed by the coupling means to cause displacement of the wall of the chamber such that the fluid is expelled from the chamber to force a drug towards the administration means.

A drug delivery device includes a container for storing a drug having a longitudinal axis. A plunger rod aligned with the longitudinal axis of the container has a first end and a second end, where the second end is disposed within the container. A stopper is disposed in and movable relative to the container for expelling the drug, and a drive mechanism is operatively coupled to the first end of the plunger rod. The drive mechanism is configured to deliver a drive force to move the plunger rod along the longitudinal axis and through the container. A chamber disposed between a plunger rod and the stopper is adapted to oppose the drive force of the drive mechanism.

A fluid delivery system is disclosed which comprises at least one supply station for supplying at least one fluid, a pressurizing unit for pressurizing said at least one fluid, an inlet fluid circuit in fluid communication with said at least one supply station and with a pump module of said pressurizing unit and an outlet fluid circuit in fluid communication with said pump module for discharging the fluid from the chamber. The chamber is provided with a piston reciprocating therein, thereby defining first and second variable-volume sub-chambers. The fluid delivery system further comprises a recirculation fluid circuit fluidically connecting said first and second variable-volume sub-chambers, and an actuator associated to said recirculation fluid circuit for managing the passage of said at least one fluid between said first and second variable-volume sub-chambers in both directions. A method of operating the fluid delivery system is also disclosed.

A fluid delivery system is disclosed which comprises at least one supply station for supplying at least one fluid, a pressurizing unit for pressurizing said at least one fluid, an inlet fluid circuit in fluid communication with said at least one supply station and with a pump module of said pressurizing unit and an outlet fluid circuit in fluid communication with said pump module for discharging the fluid from the chamber. The chamber is provided with a piston reciprocating therein, thereby defining first and second variable-volume sub-chambers. The fluid delivery system further comprises a recirculation fluid circuit fluidically connecting said first and second variable-volume sub-chambers, and an actuator associated to said recirculation fluid circuit for managing the passage of said at least one fluid between said first and second variable-volume sub-chambers in both directions. A method of operating the fluid delivery system is also disclosed.

A drug delivery device including a reservoir configured to contain a fluid to be delivered by advancing a piston in the reservoir at an advancement speed defining a delivery rate for the medicament. The device further includes an electric motor configured to drive the delivery mechanism by rotation to advance the piston at the advancement speed. The device further includes a control unit that controls a rotational speed and an on state/off state of the electric motor. The control unit determines rotational speed of the electric motor based on a back-electromagnetic force signal provided from the electric motor while operating in a monitoring mode. The control unit controls the rotational speed of the electric motor such that a back-emf signal can be detected in the monitoring mode. The control unit modulates the on state/off state of the electric motor to adjust the delivery rate of the medicament.

The present disclosure relates to a test device to be inserted into the syringe receptacle of a pump, for example for a blood treatment apparatus, for testing at least one function of the pump and/or of the blood treatment apparatus. The test device includes a holding device for releasably holding the test device on the housing of the blood treatment apparatus. In addition, the test device includes at least one movable actuator and at least one electric motor arranged to directly or indirectly move said movable actuator or a section thereof.

A method for managing delivery of medication to a patient including medication dosage control and medication flow rate control for the patient. The method comprises controlling flow rate of the medication to be delivered to the patient through a needle that is subcutaneously inserted into the patient including: monitoring glucose levels in the patient using a continuous glucose monitoring device; converting the glucose levels from the continuous glucose monitoring device into instructions by control algorithms within a microcontroller unit; commanding a pumping unit to deliver the medication through the needle at a flow rate based on the converted instructions; and delivering the medication through the needle into the patient at the flow rate; and adjusting the flow rate continually to reduce a difference between actual flow rate measured off of the pumping unit and a converted flow rate from the continuous glucose monitoring device.

A system for controlled delivery of a medical fluid may include an elastomeric pump, a valve member fluidly coupled to the elastomeric pump at one side and a catheter at an opposite side for delivering the medical fluid to a patient, and tubing fluidly coupling the elastomeric pump and the valve member. The elastomeric pump may include an elastomeric membrane and a shell surrounding the elastomeric membrane. The pressure of the medical fluid may be greater than a pressure of the vein to keep the vein open. The valve member may be movable between an initial closed position, a fully open position where the medical fluid is delivered to the vein of the patient at a predetermined fluid flow rate, and at least one intermediate open flow position where the medical fluid is delivered to the vein of the patient at a flow rate below the predetermined fluid flow rate.

A method for performing a medical procedure requiring effective, reliable and foolproof delivery of controlled amounts of a medical grade gas to a patient includes providing a compressed gas cylinder having a weight with medical grade gas sealed therein of at least twelve grams and not greater than fifty grams. The method also includes connecting the compressed gas cylinder to an integrated compressed gas unit including a regulator valve assembly positioned between an outlet port and an inlet port, wherein the regulator valve assembly includes a press button actuator and regulator adjustment dial. A flow control system is secured to the compressed gas unit and the medical grade gas is delivered in precisely controlled amounts by actuating the compressed gas unit and operating the flow control system to deliver the medical grade gas to vasculature of the patient.