A medical device includes a base having a needle channel and a first surface configured to be secured to a patient's skin. An insertable member is configured to be secured to the base with a length portion of the insertable member extending out of the needle channel at the first surface, for insertion through the patient's skin at an insertion site. A septum extends across the needle channel. The septum has a body through which an insertion needle may be selectively extended to facilitate the subcutaneous insertion of the length portion of the insertable member. The septum provides a liquid seal across the needle channel. The needle channel and the septum provide a sealed volume in which a limited amount of blood or other fluid from the insertion site may be held.

A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.

A user-initiated fluid pathway connection includes: a connection hub, a piercing member, a sterile sleeve, and a drug container having a cap, a pierceable seal, a barrel, and a plunger seal, wherein the piercing member is initially retained within the sterile sleeve between the connection hub and the pierceable seal of the drug container. The connection hub may include an internal aperture within the connection hub which functions as a flow restrictor and wherein a piercing member is connected to one end of the internal aperture and a fluid conduit is connected to another end of the internal aperture. A drug delivery pump with integrated sterility maintenance features includes a housing, upon which an activation mechanism, an insertion mechanism, a fluid pathway connection as described above, a power and control system, and a drive mechanism connected to a drug container are mounted. Methods of assembly and operation are also provided.

A method for making a fluid delivery device including a reusable portion and a disposable portion. The disposable portion is adapted to be secured to a user and includes a conduit fluidly connecting a reservoir containing a fluid and a moveable pumping member. The moveable pumping member can expand an expandable structure with the fluid. The reusable portion is selectively engageable to the disposable portion and contains a drive device for engaging the moveable pumping member of the disposable portion. The drive device has a rotatable pumping actuation member with a plurality of projections for engaging the moveable pumping member and thereby moving the fluid to expand the expandable structure.

A Huber safety needle assembly including a body, configured to receive a needle. The body further including an upper portion having a first gripping portion coupled thereto, a lower portion having a second gripping portion coupled to thereto, and a hinge mechanism. The needle having a needle tip configured to be received in the body. The hinge mechanism is configured to operably transition the body between a closed configuration and an open configuration. The closed configuration allowing at least a portion of the needle, including the needle tip, to extend below the bottom surface of the lower portion of the body. The open configuration allowing the needle tip to be securely received within the lower portion such that it does not extend below the bottom surface of the lower portion.

A syringe cartridge including a reservoir part and an extension extending from the reservoir part. The extension defining a fluid path and including a molding and a first needle extending from the molding. The extension turning to a finite angle with respect to an axis of the reservoir part and at least part of the first needle is likewise at the finite angle. At least some of the part of the first needle at the finite angle being enclosed within the molding of the fluid path. A drug delivery device may be used with the cartridge and includes a skin-contacting surface. In use the longitudinal axis of the interior of the cartridge may be disposed substantially parallel to the skin-contacting surface.

A method of dispensing a therapeutic fluid from a line includes providing an inlet line connectable to an upstream fluid source. The inlet line is in downstream fluid communication with a pumping chamber. The pumping chamber has a pump outlet. The method also includes actuating a force application assembly so as to restrict retrograde flow of fluid through the inlet while pressurizing the pumping chamber to urge flow through the pump outlet. A corresponding system employs the method.

Described herein are systems and methods for performing peritoneal dialysis. According to one aspect, the disclosure provides a sterile interface connection for connecting a water purification system to a disposable source of dialysate concentrates. The sterile interface connection can include a chamber comprising an inlet adapted to be connected to the water purification system on a proximal end and a valve on a distal end. The sterile interface connection can also include spring-loaded needle disposed in the chamber. The spring-loaded needle can move between a retracted configuration in which the spring-loaded needle is fully retracted into the chamber and the valve is closed and sealed, and an extended configuration in which the spring-loaded needle extends through the valve into the disposable source of dialysate concentrates.

A fluid channel module for an infusion set component of a fluid infusion device that delivers a fluid to a patient includes a body section comprising coupling features to mate with a base of the infusion set component. The fluid channel module includes an interior fluid flow channel formed within the body section to receive the fluid from the fluid infusion device. The fluid channel module includes a conduit having a first end in fluid communication with the interior fluid flow channel, and having a second end to deliver the fluid to the patient.

An add-on for a self-injector is described. The add-on includes an adaptor having at a rigid and a bent fluid path. The adaptor is sized and fitted to sterilely couple the bent fluid path to a tip of a fluid reservoir. The add-on also includes a fastener sized and fitted to couple a body of the fluid reservoir to the self-injector. The internal diameter of the fastener is adjustable. The adaptor and the fastener couple to the self-injector to at least one of a plurality of reservoirs having different sizes and tip types. The self-injector can include a support plate with a plurality of attachment points. The fastener can be sized and fitted to couple to the body of the fluid reservoir and to at least one of the attachment points. A retention cantilever can releasably couple the at least one fastener to the support plate.